On the persistence of the radioprotective effect of chlorophyllin (CHLN) in somatic cells of Drosophila

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 446, Issue 2, 1999, Pages 189-192

  Pimentel, E ^a   Cruces, M P ^a   Zimmering, S ^b  

^a INSTITUTO NACIONAL DE INVESTIGACIONES NUCLEARES   (Mexico)

^b BROWN UNIVERSITY   (United States)

Author keywords

Chlorophyllin; Drosophila; Persistence; Radioprotection; Somatic cells; Wing spot test

Indexed keywords

CHLOROPHYLL; SUCROSE;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GAMMA IRRADIATION; NONHUMAN; PRIORITY JOURNAL; RADIATION PROTECTION; SOMATIC CELL; TOPICAL DRUG ADMINISTRATION;

ANIMALS; CHLOROPHYLLIDES; DROSOPHILA; FEMALE; GAMMA RAYS; LARVA; MALE; MUTATION; RADIATION-PROTECTIVE AGENTS; WING;

EID: 0032761002     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(99)00182-5     Document Type: Article

References (14)

1. Ong T., Whong W., Stewart J., Brockman H.E. Comparative antimutagenicity of 5 complex mixtures in Salmonella typhimurium TA 98. Mutat. Res. 222:1989;19-25.
2. Warner J.R., Nath J., Ong T. Antimutagenicity studies of chlorophyllin using the Salmonella arabinose-resistant assay system. Mutat. Res. 262:1991;25-30.
3. Romert L.M., Curvall M., Jennssen D. Chlorophyllin is both a positive and negative modifier of mutagenesis. Mutagenesis. 7:1992;349-355.
4. 1 and two heterocyclic amines in the Salmonella mutagenicity assay. Carcinogenesis. 12:1991;939-942.
5. Dashwood R.H. Protection by chlorophyllin against the co-valent binding of 2-amino-3-methylimidazo-(4-5-f)-quinoline (IQ) to rat liver DNA. Carcinogenesis. 13:1992;113-118.
6. Ghosh A., Sen A.S., Sharma A., Talukder G. Inhibition of clastogenic effects of cesium chloride in mice in vivo by chlorophyllin. Toxicol. Lett. 57:1991;11-17.
7. Sarker D., Sharma A., Talukder G. Differential protection of chlorophyllin against clastogenic effects of chromium and chlordane in mouse bone marrow in vivo. Mutat. Res. 301:1993;33-38.
8. Negishi T., Arimoto S., Nishizaki C., Hayatsu H. Inhibitory effect of chlorophyllin on the genotoxicity of 3-amino-1-methyl-5-Hpyrido (4, 3b) indole (Trp-P-2). Carcinogenesis. 10:1989;145-149.
9. Zimmering S., Olvera O., Hernandez M.E., Cruces M.P., Arceo C., Pimentel E. Evidence for a radioprotective effect of chlorophyllin. Mutat. Res. 245:1990;47-49.
10. Olvera O., Zimmering S., Arceo C., Cruces M. The protective effect of chlorophyllin in treatment with chromium (VI) oxide in somatic cells of Drosophila. Mutat. Res. 301:1993;201-204.
11. Graf U., Wurgler F.E., Katz A.J., Frei H., Juon H., Hall C.B., Kale P.G. Somatic mutation and recombination test in Drosophila. Environ. Mutagen. 6:1984;153-188.
12. S.M. Cohen, Imaginal Disc Development, in: M. Bate, A.M. Arias (Eds.), The Development of Drosophila (1984), Vol. II, C.S.H. L Press, 1993, pp. 747-842.
13. D. Lindsley, E. Zimm, The Genome of Drosophila melanogaster, Univ. Calif., San Diego, La Jolla, CA, 1985.
14. Milan M., Campuzano S., Garcia-Bellido A. Cell cycling and patterned cell proliferation in the Drosophila wing during metamorphosis. Proc. Natl. Acad. Sci. U.S.A. 95:1996;11687-11692.