Apomorphine test: A predictor for motor responsiveness to deep brain stimulation of the subthalamic nucleus

Journal of Neurology

Volumn 246, Issue 10, 1999, Pages 907-913

  Pinter, Michaela M ^a   Alesch, Francois ^b   Murg, Monika ^a   Helscher, Reinhard J ^a   Binder, Heinrich ^a  

^a LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Apomorphine test; Deep brain stimulation; Motor response; Parkinson's disease; Subthalamic nucleus

Indexed keywords

APOMORPHINE; DOPAMINE RECEPTOR STIMULATING AGENT;

ADULT; AGED; ARTICLE; BRAIN DEPTH STIMULATION; CIRCADIAN RHYTHM; CLINICAL ARTICLE; DIAGNOSTIC VALUE; FEMALE; HUMAN; MALE; PARKINSON DISEASE; PATIENT SELECTION; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROVOCATION TEST; RATING SCALE; SHY DRAGER SYNDROME; SUBTHALAMIC NUCLEUS;

AGED; APOMORPHINE; ELECTRIC STIMULATION THERAPY; ELECTRODES, IMPLANTED; FEMALE; FINGERS; FORECASTING; HUMANS; INTRAOPERATIVE CARE; MALE; MIDDLE AGED; MOVEMENT; MULTIPLE SYSTEM ATROPHY; PARKINSON DISEASE; SUBTHALAMIC NUCLEUS; TIME FACTORS; TREATMENT OUTCOME;

EID: 0032759252     PISSN: 03405354     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004150050481     Document Type: Article

References (31)

1. Alesch F, Pinter MM, Helscher RJ, Fertl L, Benabid AL, Koos W (1995) Stimulation of the ventral intermediate thalamic nucleus in tremor dominated Parkinson's disease and essential tremor. Acta Neurochir (Wien) 136:75-81
2. Alexander GE, Crutcher MD, DeLong MR (1990) Basal ganglia thalamocortical circuits: parallel substrates for motor, oculomotor, prefrontal and limbic functions. Prog Brain Res 85:119-146
3. Aziz TZ, Peggs D, Sambrook MA, Crossman AR (1991) Lesion of the subthalamic nucleus for the alleviation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism in the primate. Mov Disord 6:288-292
4. Benabid AL, Pollak P, Gross C, Hoffmann D, Benazzouz A, Gao DM, Laurent A, Gentil M, Perret J (1994) Acute and long-term effects of subthalamic nucleus stimulation in Parkinson's disease. Stereotact Funct Neurosurg 62:76-84
5. Benazzouz A, Gross C, Féger J, Boraud T, Bioulac B (1993) Reversal of rigidity and improvement in motor performance by subthalamic high-frequency stimulation in MPTP-treated monkeys. Eur J Neurosci 5:382-389
6. Colosimo C, Merello M, Hughes AJ, Sieradzan K, Lees AJ (1996) Motor response to acute dopaminergic challenge with apomorphine and levodopa in Parkinson's disease: implications for the pathogenesis of the on-off phenomenon. J Neurol Neurosurg Psychiatry 61:634-637
7. D'Costa DF, Abbott RJ, Pye IF, Millac PAH (1991) The apomorphine test in parkinsonian syndromes. J Neurol Neurosurg Psychiatry 54:870-872
8. Delfs JM, Ciaramitaro VM, Parry TJ, Chesselet MF (1995) Subthalamic nucleus lesions: widespread effects on changes in gene expression induced by nigrostriatal dopamine depletion in rats. J Neurosci 15:6562-6575
9. Fahn S, Elton RL, Members of the UPDRS Development Committee (1987) Unified Parkinson's disease rating scale. In: Fahn S, Marsden CD, Calne DB, Goldstein M (eds) Recent developments in Parkinson's disease, vol II. Macmillian Healthcare, Florham Park, pp 153-163
10. Gerfen CR (1995) Dopamine receptor function in the basal ganglia. Clin Neuropharmacol 18:162-177
11. Gibb WRG, Lees AJ (1988) The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. J Neurol Neurosurg Psychiatry 51:745-752
12. Hoehn MM, Yahr MD (1967) Parkinsonism: onset, progression and mortality. Neurology 17:427-442
13. Hughes AJ, Lees AJ, Stern GM (1990) Apomorphine test to predict dopaminergic responsiveness in parkinsonian syndromes. Lancet 336:32-34
14. Hughes AJ, Lees AJ, Stern GM (1991) Challenge tests to predict the dopaminergic response in untreated Parkinson's disease. Neurology 41:1723-1725
15. Jenkins IH, Fernandez W, Playford ED, Lees AJ, Frackowiak RSJ, Passingham RE, Brook DJ (1992) Impaired activation of the supplementary motor area in Parkinson's disease is reversed when akinesia is treated with apomorphine. Ann Neurol 32:749-757
16. Kempster PA, Gibb WRG, Stern GM, Lees AJ (1989) Asymmetry of substantia nigra neuronal loss in Parkinson's disease and its relevance to the mechanism of levodopa related motor fluctuations. J Neurol Neurosurg Psychiatry 52:72-76
17. Kempster PA, Frankel JP, Stern GM, Lees AJ (1990) Comparison of motor response to apomorphine and levodopa in Parkinson's disease. J Neurol Neurosurg Psychiatry 53:1004-1006
18. Krack P, Pollak P, Limousin P, Benazzouz A, Benabid AL (1997) Stimulation of subthalamic nucleus alleviates tremor in Parkinson's disease. Lancet 350:1675
19. Krack P, Pollak P, Limousin P, Hofmann D, Xie J, Benazzouz A, Benabid AL (1998) Subthalamic nucleus or internal pallidal stimulation in young onset Parkinson's disease. Brain 121:451-457
20. Krack P, Limousin P, Benabid AL, Pollak P (1998) Chronic stimulation of subthalamic nucleus improves levodopa-induced dyskinesias in Parkinson's disease. Lancet 350:1676
21. Kreiss DS, Mastropietro CW, Rawji SS, Walters JR (1997) The response of subthalamic nucleus neurons to dopamine receptor stimulation in a rodent model of Parkinson's disease. J Neurosci 17:6807-6819
22. Lavoie B, Smith Y, Parent A (1989) Dopaminergic innervation of the basal ganglia in the squirrel monkey as revealed by tyrosine hydroxylase immunohistochemistry. J Comp Neurol 289:36-52
23. Lee CS, Schulzer M, Mak E, Hammerstad JP, Calne S, CalneDB (1995) Patterns of asymmetry do not change over the course of idiopathic parkinsonism: Implications for pathogenesis. Neurology 45:435-449
24. Limousin P, Pollak P, Benazzouz A, Hoffmann D, Le Bas JF, Broussolle E, Perret E, Benabid AL (1995) Effect on parkinsonian signs and symptoms of bilateral subthalamic nucleus stimulation. Lancet 345:91-95
25. Limousin P, Greene J, Pollak P, Rothwell J, Benabid AL, Frackowiak R (1997) Changes in cerebral activity pattern due to subthalamic nucleus or internal pallidum stimulation in Parkinson's disease. Ann Neurol 42:283-291
26. Mrzljak L, Bergson C, Pappy M, Huff R, Levenson R, Goldman-Rakic PS (1996) Localization of dopamine D4 receptors in GABAergic neurons of the primate brain. Nature 381:245-248
27. Pinter MM, Helscher RJ, Sattler AP (1993) Apomorphintest bei Morbus Parkinson - Dosis und korrespondierende Parameter. Wien Klin Wochenschr 16:472-475
28. Pollak P, Benabid AL, Limousin P, Benazzouz A, Hoffmann D, Le Bas JF, Perret J (1996) Subthalamic nucleus stimulation alleviates akinesia and rigidity in parkinsonian patients. Adv Neurol 69:591-594
29. Quinn N (1989) Multiple system atrophy- the nature of the beast. J Neurol Neurosurg Psychiatry [Suppl] Jun:78-89
30. Rodriguez M, Lera G, Vaamonde J, Luquin MR, Obeso JA (1994) Motor response to apomorphine and levodopa in asymmetric Parkinson's disease. J Neurol Neurosurg Psychiatry 57:562-566
31. Verhagen Metman L, Locatetli ER, Bravi D, Mouradian MM, Chase TN (1997) Apomorphine responses in Parkinson's disease and the pathogenesis of motor complications. Neurology 48:369-372