Studies on Nepalese crude drugs. XXV. Phenolic constituents of the leaves of Didymocarpus leucocalyx C. B. Clarke (Gesneriaceae)

Chemical and Pharmaceutical Bulletin

Volumn 47, Issue 10, 1999, Pages 1404-1411

  Segawa, Akiko ^a   Miyaichi, Yukinori ^a   Tomimori, Tsuyoshi ^a   Kiuchi, Fumiyuki ^b,c   Ohta, Tomihisa ^b  

^a HOKURIKU UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Anthraquinone; Didymocalyxin; Didymocarpus leucocalyx; Flavonoid; Gesneriaceae; Phenolic compound

Indexed keywords

1,4 DIHYDROXY 2,3,6,7 TETRAMETHOXY 10 PHENYL 9,10 DIHYDROCYCLOHEPTA[2,1 B]4H CHROMENE 8,11 DIONE; 1,6,8 TRIHYDROXY 4 BENZOYLOXY 3 METHYLANTHRAQUINONE; 2',5' DIHYDROXY 4' METHOXY 3',6' DIOXOCHALCONE; 2',6' DIHYDROXY 3',4' DIMETHOXYCHALCONE; 2( 2 PHENYLVINYL) 5,6 DIHYDROXY 7,8 DIMETHOXY 4H PYRANO[3,2 D]BENZO[B]FURAN 4 ONE; 2,3 DIHYDROXYPROPYL 1,6,8 TRIHYDROXY 3 METHYL 9,10 DIOXOANTHRACENE 2 CARBOXYLATE; 3 ( 1 HYDROXY 3 PHENYLPROP 2 ENYLIDENE) 7 ( 3 PHENYLPROP 2 ENOYL) 6 HYDROXY 4,5 DIMETHOXYBENZO[B]FURAN 2 ONE; 3' HYDROXY 2',4',5',6' TETRAMETHOXYCHALCONE; 3',4 DIHYDROXY 2',4',5',6' TETRAMETHOXYCHALCONE; 5 HYDROXY 6,7 DIMETHOXYFLAVONONE; 5,8 DIHYDROXY 6,7 DIMETHOXYFLAVONONE; 5,8 DIHYDROXY 6,7 DIMETHOXYISOFLAVONE; ANTHRAQUINONE DERIVATIVE; CATENARIN; DIDYMOCALYXIN; FLAVONOID; HERBACEOUS AGENT; PHYSCION; PLANT EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG DETERMINATION; DRUG ISOLATION; DRUG STRUCTURE; PLANT LEAF; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY ANALYSIS;

EID: 0032757789     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.47.1404     Document Type: Article

References (30)

1. Part XXIV: Kizu H., Sugita N., Tomimori T., Chem. Pharm. Bull., 46, 988-1000 (1998).
2. Hara H., "The Flora of Eastern Himalaya," University of Tokyo Press, Tokyo, 1966, p.298; idem, ibid., 1971, p. 122; Department of Medicinal Plants, Ministry of Forests, H.M.G. of Nepal (ed.), "Flora of Phulchoki and Godawari," Kathmandu, 1969, p.86.
3. Hara H., "The Flora of Eastern Himalaya," University of Tokyo Press, Tokyo, 1966, p.298; idem, ibid., 1971, p. 122; Department of Medicinal Plants, Ministry of Forests, H.M.G. of Nepal (ed.), "Flora of Phulchoki and Godawari," Kathmandu, 1969, p.86.
4. Hara H., "The Flora of Eastern Himalaya," University of Tokyo Press, Tokyo, 1966, p.298; idem, ibid., 1971, p. 122; Department of Medicinal Plants, Ministry of Forests, H.M.G. of Nepal (ed.), "Flora of Phulchoki and Godawari," Kathmandu, 1969, p.86.
5. Ministry of Forests and Soil Conservation, H.M.G. of Nepal (ed.), "Medicinal Plants of Nepal," Fourth Edition, Kathmandu, 1993, p. 31.
6. Namba T. (ed.), "Medicinal Resources and Ethnopharmacology in Nepal," Research Institute for Wakan-Yaku (Oriental Medicines), Toyama Medical and Pharmaceutical University, Toyama, 1983, p. 291.
7. Bohlmann F., Fritz U., Phytochemistry, 18, 1888-1889 (1979); Wu T. S., Kuoh C. S., Ho S. T., Yang M. S., Lee K. K., ibid., 20, 527-529 (1981).
8. Bohlmann F., Fritz U., Phytochemistry, 18, 1888-1889 (1979); Wu T. S., Kuoh C. S., Ho S. T., Yang M. S., Lee K. K., ibid., 20, 527-529 (1981).
9. Patra A., Mitra A. K., Bhattacharyya A., Adityachaudhury N., Org. Magn. Reson., 18, 241-242 (1982).
10. Hofle G., Tetrahedron, 33, 1963-1970 (1977); Kalidhar S. B., Phytochemistry, 28, 3459-3463 (1989).
11. Hofle G., Tetrahedron, 33, 1963-1970 (1977); Kalidhar S. B., Phytochemistry, 28, 3459-3463 (1989).
12. Morooka N., Nakano S., Itoi N., Ueno Y., Agric. Biol. Chem., 54, 1247-1252 (1990).
13. Ramakrishnan G., Baneiji A., Chadha M. S., Phytochemistry, 13, 2317-2318 (1974); Ichino K., Tanaka H., Ito K., J. Nat. Prod., 51, 906-914 (1988).
14. Ramakrishnan G., Baneiji A., Chadha M. S., Phytochemistry, 13, 2317-2318 (1974); Ichino K., Tanaka H., Ito K., J. Nat. Prod., 51, 906-914 (1988).
15. Rathore J. S., Garg S. K., Gupta S. R., Phytochemistry, 20, 1755-1756 (1981); Parmar V. S., Sharma S., Rathore J. S., Garg M., Gupta S., Malhotra S., Sharma V. K., Singh S., Magn. Reson. Chem., 28, 470-474 (1990).
16. Rathore J. S., Garg S. K., Gupta S. R., Phytochemistry, 20, 1755-1756 (1981); Parmar V. S., Sharma S., Rathore J. S., Garg M., Gupta S., Malhotra S., Sharma V. K., Singh S., Magn. Reson. Chem., 28, 470-474 (1990).
17. Bhattacharyya A., Chaudhuri A., Adityachaudhury N., Indian J. Chem., 19B, 428-429 (1980).
18. a) Mabry T. J., Markham K. R., Thomas M. B., "The Systematic Identification of Flavonoids," Springer-Verlag, New York, 1970, Chapter VII;
19. b) Chapter VI;
20. c) Chapter V.
21. Horie T., Ohtsuru Y., Shibata K., Yamashita K., Tsukayama M., Kawamura Y., Phytochemistry, 47, 865-874 (1998).
22. Pelter A., Ward R. S., Gray T. I., J. Chem. Soc., Perkin Trans., 1, 1976, 2475-2483.
23. Yoshioka I., Yamauchi H., Murata K., Kitagawa I., Chem. Pharm. Bull., 20, 1082-1084 (1972); Shibata S., Natori S., ibid., 1, 160-164 (1953).
24. Yoshioka I., Yamauchi H., Murata K., Kitagawa I., Chem. Pharm. Bull., 20, 1082-1084 (1972); Shibata S., Natori S., ibid., 1, 160-164 (1953).
25. Uzawa H., Nisida Y., Ohrui H., Meguro H., J. Org. Chem., 55, 116 (1990).
26. Chmielewska I., Cieślak J., Gorczyńska K., Kontnik B., Pitakowska K., Tetrahedron, 4, 36-42 (1958).
27. Seto H., Furihata K., Otake N., Ito Y., Takahashi S., Haneishi T., Ohuchi M., Tetrahedron Lett., 25, 337-340 (1984).
28. Fujii M., Miyaichi Y., Tomimori T., Natural Medicines, 50, 404-407 (1996).
29. Gilmore C. J.; MITHRIL - an integrated direct methods computer program. J. Appl. Cryst., 17, 42, Univ.of Glasgow,Scotland (1984).
30. All calculations were performed using the TEXSAN crystallographic software package of Molecular Structure Corporation (1985).