Hydroxyurea: Overview of clinical data and antiretroviral and immunomodulatory effects

Antiviral Therapy

Volumn 4, Issue SUPPL. 3, 1999, Pages 101-108

  Lori, Franco ^a   Lisziewicz, Julianna ^b  

^a Research Institute for Genetic and Human Therapy (RIGHT)   (Italy)

^b Research Institute for Genetic Human Therapy   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADEFOVIR; ADENOSINE DERIVATIVE; ANTIRETROVIRUS AGENT; CD4 ANTIGEN; CD8 ANTIGEN; CYTOSTATIC AGENT; DIDANOSINE; HYDROXYUREA; PYRIMIDINE NUCLEOSIDE DERIVATIVE; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE;

BONE MARROW TOXICITY; CLINICAL STUDY; CLINICAL TRIAL; CONFERENCE PAPER; DRUG SAFETY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; IMMUNOMODULATION; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; MACROPHAGE; PRIORITY JOURNAL; VIRUS INHIBITION; VIRUS REPLICATION;

ANTI-HIV AGENTS; DIDANOSINE; DRUG THERAPY, COMBINATION; HIV INFECTIONS; HIV-1; HUMANS; HYDROXYUREA; RANDOMIZED CONTROLLED TRIALS; REVERSE TRANSCRIPTASE INHIBITORS; RNA, VIRAL; STAVUDINE;

EID: 0032756555     PISSN: 13596535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (4)

1. Lori F & Lisziewicz J. Hydroxyurea: mechanisms of HIV-1 inhibition. Antiviral Therapy 1998; 3 (Supplement 4):25-33.
2. Lori F, Malykh AG, Foli A, Maserati R, De Antoni A, Minoli L, Padrini D, Degli Antoni A,.Barchi E, Jessen H, Wainberg MA, Gallo RC & Lisziewicz J. Combination of a drug treatment targeting the cell with a drug targeting the virus controls human immunodeficiency virus type 1 resistance. AIDS Research and Human Retroviruses 1997; 13:1403-1409.
3. Rutschmann OT, Opravil M, Iten A, Malinverni R, Vernazza PL, Bucher HC, Bernasconi E, Sudre P, Leduc D, Yerly S, Perrin LH & Hirschel B. A placebo-controlled trial of didanosine plus stavudine, with and without hydroxyurea, for HIV-1 infection. AIDS 1998; 12:F71-F77.
4. Federico et al. Hydroxyurea in combination regimens for the treatment of antiretroviral-naive, HIV-infected adults. 12th International AIDS Conference, 28 June-3 July 1998, Geneva, Switzerland; Abstract 287/12235.