Conformations and pharmacophores of cyclic RGD containing peptides which selectively bind integrin α(v)β3

Journal of Peptide Science

Volumn 5, Issue 11, 1999, Pages 491-506

  Locardi, Elsa ^a   Mullen, Daniel G ^b   Mattern, Ralph Heiko ^b   Goodman, Murray ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Integra LifeSciences Corporation   (United States)

Author keywords

Integrins (v) 3 and (IIb) 3; Molecular dynamics; Nuclear magnetic resonance; Peptide conformations; RGD

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; CYCLOPEPTIDE; DIMETHYL SULFOXIDE; INTEGRIN RECEPTOR; PENTAPEPTIDE; VITRONECTIN RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; LIGAND BINDING; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; PEPTIDE SYNTHESIS; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN BINDING; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OLIGOPEPTIDES; PEPTIDES, CYCLIC; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, VITRONECTIN;

EID: 0032756194     PISSN: 10752617     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1387(199911)5:11<491::AID-PSC218>3.0.CO;2-8     Document Type: Article

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