Gain of chromosome arm 17q is associated with unfavourable prognosis in neuroblastoma, but does not involve mutations in the somatostatin receptor 2 (SSTRP) gene at 17q24

British Journal of Cancer

Volumn 81, Issue 8, 1999, Pages 1402-1409

  Abel, F ^a   Ejeskar K ^a   Kogner, P ^b   Martinsson, T ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

17q; Neuroblastoma; SSTR2

Indexed keywords

SOMATOSTATIN; SOMATOSTATIN RECEPTOR;

ARTICLE; CANCER STAGING; CANCER SURVIVAL; CHROMOSOME 17Q; CHROMOSOME ARM; CLINICAL ARTICLE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE MUTATION; HUMAN; MALE; NEUROBLASTOMA; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; SINGLE STRAND CONFORMATION POLYMORPHISM;

EID: 0032755289     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6692231     Document Type: Article

References (26)

1. Ambros PE, Ambros IM, Strehl S, Bauer S, Luegmayr A, Kavar H, Ladenstein R, Fink FM, Horcher E, Printz G, et al (1995) Regression and progression in neuroblastoma. Does genetics predict Tumur behaviour? Eur J Cancer 31A: 510-515
2. Bell GI, Yasuda K, Kong H, Law SF, Raynor K and Reisine T (1995) Molecular biology of somatostatin receptors. Ciha Found Symp 190: 65-88
3. Brodeur GM (1998) Clinical and biological aspects of neuroblastoma. In: The Genetic Basis of Human Cancer, Vogelstein B and Kinzler KW (eds), pp. 691-711. McGraw-Hill: New York
4. Brodeur GM, Pritchard J, Berthold F, Carlsen NL, Castel V, Castelberry RP, De Bernardi B, Evans AE, Favrot M, Hedborg F, et al (1993) Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. J Clin Oncol II: 1466-1477
5. Caron H, van Sluis P, van Roy N, de Kraker J, Speleman F, Voute PA, Westerveld A, Slater R and Veersteg R (1994) Recurrent 1;17 translocations in human neuroblastoma reveal nonhomologous mitotic recombination during the S/G2 phase as a novel mechanism for loss of heterozygosity. Am J Hum Genet 55: 341-347
6. Caron H, van Sluis P, van Roy N, de Kraker J, Bokkerink J, Egeler M, Laureys G, Slater R, Westerveld A, Voute PA and Versteeg R (1996) Allelic loss of chromosome Ip as a predictor of unfavourable outcome in patients with neuroblastoma. N Engl J Med 334: 225-230
7. Dib C, Faure S, Fizames C, Samson D, Drouot N, Vignal A, Millasseau P, Marc S, Hazan J, Seboun E, Lathrop M, Gyapay G, Morissette J and Weissenbach J (1996) A comprehensive genetic map of the human genome based on 5264 microsatellites. Nature 380: 152-154
8. Gale G, D'Angio G, Uri A, Chatten J and Koop CE (1982) Cancer in neonates: the experience at the children's hospital of Philadelphia. Pediatrics 70: 409-413
9. Kogner P, Borgström P, Bjellerup P, Schilling FH, Refai E, Jonsson C, Dominici C, Wassberg E, Bihl H, Jacobsson H, Theodorsson E and Hassan M (1997) Somatostatin in neuroblastoma and ganglioneuroma. Eur J Cancer 33: 2084-2089
10. Lastowska M, Cotterill S, Pearson ADJ, Roberts P, McGuckin A, Lewis I and Bown N (1997a) Gain of chromosome arm 17q predicts unfavorable outcome in neuroblastoma patients. Eur J Cancel 33: 1627-1633
11. Lastowska M, Roberts P, Pearson ADJ, Lewis I, Wolstenholme J and Bown N (1997b) Promiscuous translocations of chromosome arm 17q in human neuroblastomas. Genes Chromosomes Cancer 19: 143-149
12. Lastowska M, Van Roy N, Bown N, Speleman F, Lunec J, Strachan T, Pearson ADJ and Jackson MS (1998) Molecular cytogenetic delineation of 17q translocation breakpoints in neuroblastoma cell lines. Genes Chromosomes Cancer 23: 116-122
13. Look AT, Hayes FA, Shuster JJ, Douglass EC, Castleberry RP, Bowman LC, Smith EI and Brodeur GM (1991) J Clin Oncol 9: 581-591
14. Martinsson T, Sjöberg RM, Hedborg F and Kogner P (1995) Deletion of Ip loci and microsatellite instability in neuroblastomas analyzed with short-tandem repeat polymorphism. Cancer Res 55: 5681-5686
15. Martinsson T, Sjöberg RM, Hallstensson K, Nordling M, Hedborg F and Kogner P (1997) Delimitation of a critical tumor suppressor region at distal Ip in neuroblastoma tumors. Eur J Cancer 33: 1997-2001
16. Meddeb M, Danglot G, Chudoba I, Vénaut AM, Bénard J, Avet-Loiseau H, Vasseur B, Le Paslier D, Terrier-Lacombe MJ, Hartmann O and Bernheim A (1996) Additional copies of a 25 Mh chromosomal region originating from 17q23.1 17qter are present in 90% of high-grade neuroblastomas. Genes Chromosomes Cancer 17: 156-165
17. Patel YC, Greenwood MT, Kem G, Panetta R and Srikant CB (1993) Multiple gene transcripts of the somatostatin receptor SSTR2: Tissue selective distribution and cAMP regulation. Biochem Biophys Res Commun 192: 288-294
18. Patel YC, Greenwood MT, Panetta R, Demehyshyn L, Niznik H and Srikant CB (1995) The somatostatin receptor family. Life Sci 57: 1249-1265
19. Plantaz D, Mohapatra G, Matthay KK, Pellarin M, Seeger RC and Feuerenstein BG (1997) Gain of chromosome 17 is the most frequent abnormality detected in neuroblastoma by comparative genomic hybridization. Am J Pathol 150: 81-89
20. Schilling FH, Ambros PF, Bihl H, Martinsson T, Ambros IM, Borgström P, Jacobsson H, Falkmer UG, Treuner J and Kogner P (1998) Somatostatin receptor expression in vivo is absent in neuroblastomas showing distal deletion of chromosome Ip and di/tetraploid DNA content. Eur J Cancer (in press)
21. Seeger RC, Brodeur GM, Sather H, Dalton A, Siegel SE, Wong KY and Hammond D (1985) Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Eng J Med 313: 1111-1116
22. Sestini R, Orlando C, Peri A, Tricarico C, Pazzagli M, Serio M, Pagani A, Bussolati G, Ganchi S and Maggi M (1996) Quantitation of somatostatin receptor type 2 gene expression in neuroblastoma cell lines and primary tumors using competitive reverse transcription-polymerase chain reaction. Clin Cancer Res 2: 1757-1765
23. Vandesompele J, Van Roy N, Van Gele M, Laureys G, Ambros P, Heimann P, Devalck C, Schuuring E, Brock P, Otten J, Gyselinck J, De Paepe A and Speleman F (1998) Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization. Genes Chromosomes Cancer 23: 141-152
24. Van Roy N, Laureys G, Cheng NG, Willem P, Opdenakker G, Versteeg R and Speleman F (1994) 1;17 translocations and other chromosome 17 rearrangements in human primary tumor neuroblastoma tumors and cell lines. Genes Chromosomes Cancer 10: 103-114
25. Yamada Y, Post SR, Wang K, Tager HS, Bell GI and Seino S (1992) Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastronal tract, and kidneys. Proc Natl Acad Sci USA 89: 251-255
26. Zhang CY, Yokogoshi Y, Yoshimoto K, Fujinaka Y, Matsumoto K and Saito S (1995) Point mutation of the somatostatin receptor 2 gene in the human small cell lung cancer cell line COR-L103. Biochem Biophys Res Commun 210: 805-815