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Volumn 18, Issue SUPPL. 2, 1999, Pages 53-67

Special report: Reproductive and developmental toxicity of ethylene glycol and its ethers

Author keywords

[No Author keywords available]

Indexed keywords

2 ETHOXYETHANOL; 2 METHOXYETHANOL; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; ETHYLENE GLYCOL; ETHYLENE GLYCOL DERIVATIVE;

EID: 0032754315     PISSN: 10915818     EISSN: None     Source Type: Journal    
DOI: 10.1080/109158199225350     Document Type: Article
Times cited : (15)

References (61)
  • 2
    • 0028598559 scopus 로고
    • Final report on the safety assessment of Propylene Glycol and Polypropylene Glycols
    • Andersen, F. A. 1994. Final report on the safety assessment of Propylene Glycol and Polypropylene Glycols. J. Am. Coll. Toxicol. 13:437-491.
    • (1994) J. Am. Coll. Toxicol. , vol.13 , pp. 437-491
    • Andersen, F.A.1
  • 3
    • 0030457002 scopus 로고    scopus 로고
    • Final report of the safety assessment of Butoxyethanol
    • Andersen, F. A. 1996. Final report of the safety assessment of Butoxyethanol. J. Am. Coll. Toxicol. 15:462-526.
    • (1996) J. Am. Coll. Toxicol. , vol.15 , pp. 462-526
    • Andersen, F.A.1
  • 4
    • 0022770071 scopus 로고
    • Methoxyacetic acid and ethoxyacetic acid inhibit mitochondrial function in vitro
    • Beattie, P. J., and M. J. Brabec. 1986. Methoxyacetic acid and ethoxyacetic acid inhibit mitochondrial function in vitro. J. Biochem. Toxicol. 1:61-70.
    • (1986) J. Biochem. Toxicol. , vol.1 , pp. 61-70
    • Beattie, P.J.1    Brabec, M.J.2
  • 5
    • 0019968935 scopus 로고
    • Quantitative correspondence between the in vivo and in vitro activity of teratogenic agents
    • Braun, A. G., C. A. Buckner, D. J. Emerson, and B. B. Nichinson. 1982. Quantitative correspondence between the in vivo and in vitro activity of teratogenic agents. Proc. Natl. Acad. Sci. USA 79: 2056-2060.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 2056-2060
    • Braun, A.G.1    Buckner, C.A.2    Emerson, D.J.3    Nichinson, B.B.4
  • 6
    • 0028387675 scopus 로고
    • An integrated perspective on the developmental toxicity of ethylene glycol
    • Carney, E. W. 1994. An integrated perspective on the developmental toxicity of ethylene glycol. Reprod. Toxicol. 8:99-113.
    • (1994) Reprod. Toxicol. , vol.8 , pp. 99-113
    • Carney, E.W.1
  • 7
    • 0029864856 scopus 로고    scopus 로고
    • Identification of proximate toxicant for ethylene glycol developmental toxicity using rat whole embryo culture
    • Carney, E. W., A. B. Liberacki, M. J. Bartels, and W. J. Breslin. 1996. Identification of proximate toxicant for ethylene glycol developmental toxicity using rat whole embryo culture. Teratology 53:38-46.
    • (1996) Teratology , vol.53 , pp. 38-46
    • Carney, E.W.1    Liberacki, A.B.2    Bartels, M.J.3    Breslin, W.J.4
  • 8
    • 0021285109 scopus 로고
    • Effects of ethylene glycol monomethyl ether on various parameters of testicular function in the F344 rat
    • Chapin, R. E., and J. C. Lamb. 1984. Effects of ethylene glycol monomethyl ether on various parameters of testicular function in the F344 rat. Environ Health Perspect. 57:219-224.
    • (1984) Environ Health Perspect. , vol.57 , pp. 219-224
    • Chapin, R.E.1    Lamb, J.C.2
  • 9
    • 77957182317 scopus 로고
    • Effects of ethylene glycol monomethyl ether (EGME) on mating performance and epididymal sperm parameters in F344 rats
    • Chapin, R. E., S. L. Dutton, M. D. Ross, and J. C. Lamb. 1985. Effects of ethylene glycol monomethyl ether (EGME) on mating performance and epididymal sperm parameters in F344 rats. Fundam. Appl. Toxicol. 5:182-189.
    • (1985) Fundam. Appl. Toxicol. , vol.5 , pp. 182-189
    • Chapin, R.E.1    Dutton, S.L.2    Ross, M.D.3    Lamb, J.C.4
  • 11
    • 0028036037 scopus 로고
    • Cytogenic effects of 2-methoxyethanol and its metabolite, methoxyacetaldehyde, in mammalian cells in vitro
    • Chiewchanwit, T., and W. W. Au. 1994. Cytogenic effects of 2-methoxyethanol and its metabolite, methoxyacetaldehyde, in mammalian cells in vitro. Mutat. Res. 320:125-132.
    • (1994) Mutat. Res. , vol.320 , pp. 125-132
    • Chiewchanwit, T.1    Au, W.W.2
  • 12
    • 26444533588 scopus 로고
    • Embryo dosimetry and incidence of malformations in CD-1 mice following subcutaneous infusion of 2-methoxyethanol (2-ME)
    • Clarke, D. O., J. M. Duignan, and F. Welsch. 1990. Embryo dosimetry and incidence of malformations in CD-1 mice following subcutaneous infusion of 2-methoxyethanol (2-ME). Teratology 41:544.
    • (1990) Teratology , vol.41 , pp. 544
    • Clarke, D.O.1    Duignan, J.M.2    Welsch, F.3
  • 20
    • 0022407440 scopus 로고
    • A quantitative study of stage-specific spermatocyte damage following administration of ethylene glycol monomethyl ether in the rat
    • Creasy, D. M., J. C. Flynn, T. J. Gray, and W H. Butler. 1985. A quantitative study of stage-specific spermatocyte damage following administration of ethylene glycol monomethyl ether in the rat. Exp. Mol. Pathol. 43:321-336.
    • (1985) Exp. Mol. Pathol. , vol.43 , pp. 321-336
    • Creasy, D.M.1    Flynn, J.C.2    Gray, T.J.3    Butler, W.H.4
  • 21
    • 0024852374 scopus 로고
    • Propanediol-induced alterations in membrane integrity, metabolism, and developmental potential of mouse zygotes
    • Damian, M., A. A. Luciano, and J. J. Peluso. 1989. Propanediol-induced alterations in membrane integrity, metabolism, and developmental potential of mouse zygotes. Hum. Reprod. 4:969-974.
    • (1989) Hum. Reprod. , vol.4 , pp. 969-974
    • Damian, M.1    Luciano, A.A.2    Peluso, J.J.3
  • 22
    • 0025342927 scopus 로고
    • Propanediol alters intracellular pH and developmental potential of mouse zygotes independently of volume change
    • Damian, M., A. A. Luciano, and J. J. Peluso. 1990. Propanediol alters intracellular pH and developmental potential of mouse zygotes independently of volume change. Hum. Reprod. 5:212-216.
    • (1990) Hum. Reprod. , vol.5 , pp. 212-216
    • Damian, M.1    Luciano, A.A.2    Peluso, J.J.3
  • 24
    • 0021285107 scopus 로고
    • Testicular toxicity produced by ethylene glycol monomethyl and monoethyl ethers in the rat
    • Foster, P. M., D. M. Creasy, J. R. Foster, and T. J. Gray. 1984. Testicular toxicity produced by ethylene glycol monomethyl and monoethyl ethers in the rat. Environ. Health Perspect. 57:207-217.
    • (1984) Environ. Health Perspect. , vol.57 , pp. 207-217
    • Foster, P.M.1    Creasy, D.M.2    Foster, J.R.3    Gray, T.J.4
  • 25
    • 0021864640 scopus 로고
    • Studies on the toxicity of some glycol ethers and alkoxyacetic acids in primary testicular cell cultures
    • Gray, J. B., E. J. Moss, D. M. Creasy, and S. D. Gangolli. 1985. Studies on the toxicity of some glycol ethers and alkoxyacetic acids in primary testicular cell cultures. Toxicol. Appl. Pharmacol. 79:490-501.
    • (1985) Toxicol. Appl. Pharmacol. , vol.79 , pp. 490-501
    • Gray, J.B.1    Moss, E.J.2    Creasy, D.M.3    Gangolli, S.D.4
  • 26
    • 0021285135 scopus 로고
    • Developmental toxicity of four glycol ethers applied cutaneously to rats
    • Hardin, B. D., P. T. Goad, and J. R. Burg. 1984. Developmental toxicity of four glycol ethers applied cutaneously to rats. Environ. Health Perspect. 57:69-74.
    • (1984) Environ. Health Perspect. , vol.57 , pp. 69-74
    • Hardin, B.D.1    Goad, P.T.2    Burg, J.R.3
  • 27
    • 0022997928 scopus 로고
    • Methanol and ethylene glycol poisonings: Mechanism of toxicity, clinical course, diagnosis and treatment
    • Jacobsen, D., and K. E. McMartin. 1986. Methanol and ethylene glycol poisonings: Mechanism of toxicity, clinical course, diagnosis and treatment. Med. Toxicol. 1:309-344.
    • (1986) Med. Toxicol. , vol.1 , pp. 309-344
    • Jacobsen, D.1    McMartin, K.E.2
  • 29
    • 0027519446 scopus 로고
    • Effect of dose on the disposition of 2-Ethoxyethanol after inhalation by F344/N rats
    • Kennedy, C. H., I. Y. Chang, and R. F. Henderson. 1993. Effect of dose on the disposition of 2-Ethoxyethanol after inhalation by F344/N rats. Fundam. Appl. Toxicol. 21:486-491.
    • (1993) Fundam. Appl. Toxicol. , vol.21 , pp. 486-491
    • Kennedy, C.H.1    Chang, I.Y.2    Henderson, R.F.3
  • 30
    • 0025736858 scopus 로고
    • Chemically induced alterations in maternal homeostasis and histology of conceptus: Their etiologic significance in rat fetal anomalies
    • Khera, K. S. 1991. Chemically induced alterations in maternal homeostasis and histology of conceptus: Their etiologic significance in rat fetal anomalies. Teratology 44:259-297.
    • (1991) Teratology , vol.44 , pp. 259-297
    • Khera, K.S.1
  • 34
    • 0023232680 scopus 로고
    • Metabolism and disposition of glycol ethers
    • Miller, R. R. 1987. Metabolism and disposition of glycol ethers. Drug Metab. Rev. 18:1-22.
    • (1987) Drug Metab. Rev. , vol.18 , pp. 1-22
    • Miller, R.R.1
  • 35
    • 77957176825 scopus 로고
    • Ethylene glycol monomethyl ether. I. Subchronic vapor inhalation study with rats and rabbits
    • Miller, R. R., J. A. Ayres, J. T. Young, and M. J. McKenna. 1983. Ethylene glycol monomethyl ether. I. Subchronic vapor inhalation study with rats and rabbits. Fundam. Appl. Toxicol. 3:49-54.
    • (1983) Fundam. Appl. Toxicol. , vol.3 , pp. 49-54
    • Miller, R.R.1    Ayres, J.A.2    Young, J.T.3    McKenna, M.J.4
  • 36
    • 0021285112 scopus 로고
    • Ethylene glycol monomethyl ether and propylene glycol monomethyl ether: Metabolism, disposition, and subchronic inhalation toxicity studies
    • Miller, R. R., E. A. Hermann, J. T. Young, T. D. Laundry, and L. L. Calhoun. 1984. Ethylene glycol monomethyl ether and propylene glycol monomethyl ether: Metabolism, disposition, and subchronic inhalation toxicity studies. Environ. Health Perspect. 57:233-239.
    • (1984) Environ. Health Perspect. , vol.57 , pp. 233-239
    • Miller, R.R.1    Hermann, E.A.2    Young, J.T.3    Laundry, T.D.4    Calhoun, L.L.5
  • 42
    • 26444565457 scopus 로고
    • NTP Technical Report Series No. 413, NIH Publication No. 93-3144. Research Triangle Park, NC: NTP
    • 1 mice (feed studies). NTP Technical Report Series No. 413, NIH Publication No. 93-3144. Research Triangle Park, NC: NTP.
    • (1993) 1 Mice (Feed Studies)
  • 43
    • 0005764601 scopus 로고
    • NTP Toxicity Report Series No. 26, NIH Publication No. 93-3349. Research Triangle Park, NC: NTP
    • 1 mice. NTP Toxicity Report Series No. 26, NIH Publication No. 93-3349. Research Triangle Park, NC: NTP.
    • (1993) 1 Mice
  • 44
    • 0029103112 scopus 로고
    • Determination of a no-observed-effect level for developmental toxicity of ethylene glycol administered by gavage to CD rats and CD-1 mice
    • Neeper-Bradley, T. L., R. W. Tyl, L. C. Fisher, M. F. Kubena, M. A. Vrbanic, and P. E. Losco. 1995. Determination of a no-observed-effect level for developmental toxicity of ethylene glycol administered by gavage to CD rats and CD-1 mice. Fundam. Appl. Toxicol. 27:121-130.
    • (1995) Fundam. Appl. Toxicol. , vol.27 , pp. 121-130
    • Neeper-Bradley, T.L.1    Tyl, R.W.2    Fisher, L.C.3    Kubena, M.F.4    Vrbanic, M.A.5    Losco, P.E.6
  • 46
    • 0021340836 scopus 로고
    • Behavioral and neurochemical alterations in the offspring of rats after maternal or paternal inhalation exposure to the industrial solvent 2-Methoxyethanol
    • Nelson, B. K., W. S. Brightwell, J. R. Burg, and V. J. Massari. 1984. Behavioral and neurochemical alterations in the offspring of rats after maternal or paternal inhalation exposure to the industrial solvent 2-Methoxyethanol. Pharmacol. Biochem. Behav. 20:269-279.
    • (1984) Pharmacol. Biochem. Behav. , vol.20 , pp. 269-279
    • Nelson, B.K.1    Brightwell, W.S.2    Burg, J.R.3    Massari, V.J.4
  • 47
    • 0024316571 scopus 로고
    • Effects of 2-Methoxyethanol on fetal development, postnatal behavior, and embryonic intracellular pH in rats
    • Nelson, B. K., C. V. Vorhees, W. J. Scott, and L. Hastings. 1989. Effects of 2-Methoxyethanol on fetal development, postnatal behavior, and embryonic intracellular pH in rats. Neurotox. Teratol. 11:273-284.
    • (1989) Neurotox. Teratol. , vol.11 , pp. 273-284
    • Nelson, B.K.1    Vorhees, C.V.2    Scott, W.J.3    Hastings, L.4
  • 48
    • 0017595398 scopus 로고
    • Similarity of the mechanism of chemical carcinogen-initiated teratogenesis and carcinogenesis in mice
    • Nomura, T. 1977. Similarity of the mechanism of chemical carcinogen-initiated teratogenesis and carcinogenesis in mice. Cancer Res. 37:969-973.
    • (1977) Cancer Res. , vol.37 , pp. 969-973
    • Nomura, T.1
  • 49
    • 0027350830 scopus 로고
    • Ethylene glycol monomethyl ether (EGME) exposure of male mice produces a decrease in cell proliferation of preimplantation embryos
    • Oudiz, D. J., K. Walsh, and L. M. Wiley. 1993. Ethylene glycol monomethyl ether (EGME) exposure of male mice produces a decrease in cell proliferation of preimplantation embryos. Reprod. Toxicol. 7:101-109.
    • (1993) Reprod. Toxicol. , vol.7 , pp. 101-109
    • Oudiz, D.J.1    Walsh, K.2    Wiley, L.M.3
  • 50
  • 52
    • 0021869413 scopus 로고
    • Teratogenicity of dimethoxyethyl phthalate and its metabolites methoxyethanol and methoxyacetic acid in the rat
    • Ritter, E. J., W. J. Scott, Jr., J. L. Randall, and J. M. Ritter. 1985. Teratogenicity of dimethoxyethyl phthalate and its metabolites methoxyethanol and methoxyacetic acid in the rat. Teratology 32:25-31.
    • (1985) Teratology , vol.32 , pp. 25-31
    • Ritter, E.J.1    Scott Jr., W.J.2    Randall, J.L.3    Ritter, J.M.4
  • 53
    • 0024507050 scopus 로고
    • Teratologic potential of 2-methoxyethanol and transplacental distribution of its metabolite, 2-methoxy acetic acid, in non-human primates
    • Scott, W. J., R. Fradkin, W. Wittfoht, and H. Nau. 1989. Teratologic potential of 2-methoxyethanol and transplacental distribution of its metabolite, 2-methoxy acetic acid, in non-human primates. Teratology 39:363-373.
    • (1989) Teratology , vol.39 , pp. 363-373
    • Scott, W.J.1    Fradkin, R.2    Wittfoht, W.3    Nau, H.4
  • 54
    • 0028790205 scopus 로고
    • In vitro skin penetration of ethylene glycol using excised skin from mice and humans
    • Sun, J. D., S. W. Frantz, and J. L. Beskitt. 1995. In vitro skin penetration of ethylene glycol using excised skin from mice and humans. J. Toxicol. Cut. Ocular Toxicol. 14:273-286.
    • (1995) J. Toxicol. Cut. Ocular Toxicol. , vol.14 , pp. 273-286
    • Sun, J.D.1    Frantz, S.W.2    Beskitt, J.L.3
  • 55
    • 77957186092 scopus 로고
    • Assessment of the developmental toxicity of ethylene glycol applied cutaneously to CD-1 mice
    • Tyl, R. W., L. C. Fisher, M. F. Kubena, M. A. Vrbanic, and P. E. Losco. 1995a. Assessment of the developmental toxicity of ethylene glycol applied cutaneously to CD-1 mice. Fundam. Appl. Toxicol. 27:155-166.
    • (1995) Fundam. Appl. Toxicol. , vol.27 , pp. 155-166
    • Tyl, R.W.1    Fisher, L.C.2    Kubena, M.F.3    Vrbanic, M.A.4    Losco, P.E.5
  • 57
    • 9444272972 scopus 로고
    • Determination of a developmental toxicity "no observable effect level" (NOEL) for ethylene glycol (EG) by gavage in Swiss mice
    • Tyl, R. W., L. C. Fisher, M. F. Kubena, P. E. Losco, and M. A. Vrbanic. 1989. Determination of a developmental toxicity "no observable effect level" (NOEL) for ethylene glycol (EG) by gavage in Swiss mice. Teratology 39:487.
    • (1989) Teratology , vol.39 , pp. 487
    • Tyl, R.W.1    Fisher, L.C.2    Kubena, M.F.3    Losco, P.E.4    Vrbanic, M.A.5
  • 58
    • 0027190439 scopus 로고
    • Developmental toxicity evaluation of ethylene glycol by gavage in New Zealand White rabbits
    • Tyl, R. W., C. J. Price, M. C. Marr, and C. B. Myers. 1993. Developmental toxicity evaluation of ethylene glycol by gavage in New Zealand White rabbits. Fundam. Appl. Toxicol. 20:402-412.
    • (1993) Fundam. Appl. Toxicol. , vol.20 , pp. 402-412
    • Tyl, R.W.1    Price, C.J.2    Marr, M.C.3    Myers, C.B.4
  • 59
    • 0021473312 scopus 로고
    • Inhibition of intercellular communication between normal human embryonal palatal mesenchyme cells by teratogenic glycol ethers
    • Welsch, F., and D. B. Stedman. 1984a. Inhibition of intercellular communication between normal human embryonal palatal mesenchyme cells by teratogenic glycol ethers. Environ. Health Perspect. 57:125-133.
    • (1984) Environ. Health Perspect. , vol.57 , pp. 125-133
    • Welsch, F.1    Stedman, D.B.2
  • 60
    • 0021191517 scopus 로고
    • Inhibition of metabolic cooperation between Chinese Hamster V79 cells by structurally diverse teratogens
    • Welsh, F., and D. B. Stedman. 1984b. Inhibition of metabolic cooperation between Chinese Hamster V79 cells by structurally diverse teratogens. Teratog. Carcinog. Mutagen 4:285-301.
    • (1984) Teratog. Carcinog. Mutagen , vol.4 , pp. 285-301
    • Welsh, F.1    Stedman, D.B.2
  • 61
    • 0022596022 scopus 로고
    • The teratogenic potential and dose-response of dermally administered ethylene glycol monomethyl ether (EGME) estimated in rats with the Chernoff-Kavlock assay
    • Wickramaratne, G. A. de S. 1986. The teratogenic potential and dose-response of dermally administered ethylene glycol monomethyl ether (EGME) estimated in rats with the Chernoff-Kavlock assay. J. Appl. Toxicol. 6:165-166.
    • (1986) J. Appl. Toxicol. , vol.6 , pp. 165-166
    • Wickramaratne, G.A.D.S.1


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