Psychiatric inpatients and chromosome deletions within 22q11.2

Journal of Neurology Neurosurgery and Psychiatry

Volumn 67, Issue 6, 1999, Pages 803-806

  Sugama, Seiichi ^a,c   Namihira, Tomoo ^a   Matsuoka, Rumiko ^b   Taira, Naoki ^a   Eto, Yoshikatsu ^c   Maekawa, Kihei ^c  

^a Amekudai Hospital   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Chromosome 22q11.2 deletion; Psychiatric symptoms; Schizophrenia; Velocardiofacial syndrome

Indexed keywords

CHLORPROMAZINE; HALOPERIDOL;

ADULT; ARTICLE; CHROMOSOME 22Q; CHROMOSOME ANALYSIS; CHROMOSOME DELETION; CLEFT PALATE; FACE DYSMORPHIA; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HYPOPARATHYROIDISM; MAJOR CLINICAL STUDY; MENTAL DISEASE; PRIORITY JOURNAL; SCHIZOPHRENIA; VELOCARDIOFACIAL SYNDROME;

EID: 0032753685     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.67.6.803     Document Type: Article

References (11)

1. Shprintzen RJ, Goldberg RB, Lewin ML, et al. A new syndrome involving cleft palate, cardiac anomalies, typical facies, and learning disabilities: velo-cardio-facial syndrome. Cleft Palate Journal 1978;15:56-62.
2. Driscoll DA, Spinner NB, Budarf ML, et al. Deletions and microdeletions of 22q 11.2 in velo-cardio-facial syndrome. Am J Med Genet 1992;44:261-8.
3. Shprintzen RJ, Goldberg R, Golding-Kushner KJ, et al. Late-onset psychosis in the velo-cardio-facial syndrome. Am J Med Genet 1992;42:141-2.
4. Papolos DF, Faedda GL, Veit S, et al. Bipolar spectrum disorders in patients diagnosed with velo-cardio-facial syndrome: does hemizygous deletion of chromosome 22q11 result in bipolar affective disorder? Am J Psychiatry 1996;153:1541-7.
5. Karayiorgou M, Morris MA, Morrow B, et al. Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11. Proc Natl Acad Sci USA 1995;92: 7612-6.
6. Shprintzen RJ. Velocardiofacial syndrome and Digeorge sequence. J Med Genet 1994;31:423-4
7. Matsuoka R, Kimura M, Scambler PJ, et al. Molecular and clinical study of 183 patients with conotruncal anomaly face syndrome. Hum Genet 1998;103:70-80.
8. Gothelf D, Frisch A, Munitz H, et al. Velocardiofacial manifestations and microdeletions in schizophrenic inpatients. Am J Med Genet 1997;72:455-61.
9. Lachman HM, Morrow B, Shprintzen R, et al. Association of codon 108/158 catechol-o-methyltransferase gene polymorphism with the psychiatric manifestations of velocardio-facial syndrome. Am J Med Genet 1996;67:468-72.
10. Lane A, Kinsella A, Murphy P, et al. The anthropometric assessment of dysmorphic features in schizophrenia as an index of its developmental origins. Psychol Med 1997;27: 1155-64.
11. Golding-Kushner KJ, Weller G, Shprintzen RJ. Velo-cardiofacial syndrome: language and psychological profiles. J Craniofaci Genet Dev Biol 1985;5:259-66.