Assessing the function of the Ro ribonucleoprotein complex using Caenorhabditis elegans as a biological tool

Biochemistry and Cell Biology

Volumn 77, Issue 4, 1999, Pages 349-354

  Labbé, Jean Claude ^a   Hekimi, Siegfried ^b   Rokeach, Luis A ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Caenorhabditis elegans; Quality control; Ro ribonucleoprotein complex; ROP 1; Small RNAs

Indexed keywords

RIBONUCLEOPROTEIN;

AMINO ACID SEQUENCE; CAENORHABDITIS ELEGANS; CONFERENCE PAPER; NONHUMAN; OOCYTE; PHENOTYPE; PROTEIN DETERMINATION; SEQUENCE HOMOLOGY; SJOEGREN SYNDROME; SYSTEMIC LUPUS ERYTHEMATOSUS; XENOPUS;

ANIMALS; AUTOANTIGENS; CAENORHABDITIS ELEGANS; HUMANS; MODELS, BIOLOGICAL; RIBONUCLEOPROTEINS; RNA, SMALL CYTOPLASMIC;

CAENORHABDITIS ELEGANS;

EID: 0032753341     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/bcb-77-4-349     Document Type: Conference Paper

References (55)

1. Alspaugh, M.A., and Tan, E.M. 1975. Antibodies to cellular antigens in Sjögren's syndrome. J. Clin. Invest. 55: 1067-1073.
2. Belsham, G.J., Sonenberg, N., and Svitkin, Y.V. 1995. The role of the La autoantigen in internal initiation. Curr. Top. Microbiol. Immunol. 203: 85-98.
3. Ben-Chetrit, E., Chan, E.K., Sullivan, K.F., and Tan, E.M. 1988. A 52-kD protein is a novel component of the SS-A/Ro antigenic particle. J. Exp. Med. 167: 1560-1571.
4. Boire, G., Gendron, M., Monast, N., Bastin, B., and Ménard, H.A. 1995. Purification of antigenically intact Ro ribonucleoproteins; biochemical and immunological evidence that the 52-kD protein is not a Ro protein. Clin. Exp. Immunol. 100: 489-498.
5. Clark, G., Reichlin, M., and Tomasi, T.B. 1969. Characterization of a soluble cytoplasmic antigen reactive with sera from patients with systemic lupus erythematosus. J. Immunol. 102: 117-122.
6. Craig, A.W.B., Svitkin, Y.V., Lee, H.S., Belsham, G.J., and Sonenberg, N. 1997. The La autoantigen contains a dimerization domain that is essential for enhancing translation. Mol. Cell. Biol. 17: 163-169.
7. Deutscher, S.L., Harley, J.B., and Keene, J.D. 1988. Molecular analysis of the 60-kDa human Ro ribonucleoprotein. Proc. Natl. Acad. Sci. U.S.A. 85: 9479-9483.
8. Epstein, H.F., and Shakes, D.C. (editors). 1995. Caenorhabditis elegans: modem biological analysis of an organism. Academic Press, San Diego, Calif.
9. Fan, H., Sakulich, A.L., Goodier, J.L., Zhang, X.L., Qin, J., and Maraia, R.J. 1997. Phosphorylation of the human La antigen on serine 366 can regulate recycling of RNA polymerase III transcription complexes. Cell, 88: 707-715.
10. Fan, H., Goodier, J.L., Chamberlain, J.R., Engelke, D.R., and Maraia, R.J. 1998. 5′ processing of tRNA precursors can be modulated by the human La antigen phosphoprotein. Mol. Cell. Biol. 18: 3201-3211.
11. Farris, A.D., O'Brien, C.A., and Harley, J.B. 1995. Y3 is the most conserved small RNA component of Ro ribonucleoprotein complexes in vertebrate species. Gene, 154: 193-198.
12. Farris, A.D., Puvion-Dutilleul, F., Puvion, E., Harley, J.B., and Lee, L.A. 1997. The ultrastructural localization of 60-kDa Ro protein and human cytoplasmic RNAs - association with novel electron-dense bodies. Proc. Natl. Acad Sci. U.S.A. 94: 3040-3045.
13. Farris, A.D., Koelsch, G., Pruijn, G.J.M., van Venrooij, W.J., and Harley, J.B. 1999. Conserved features of Y RNAs revealed by automated phylogenetic secondary structure analysis. Nucleic Acids Res. 27: 1070-1078.
14. Fire, A., Xu, S.Q., Montgomery, M.K., Kostas, S.A., Driver, S.E., and Mello, C.C. 1998. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (London), 391: 806-811.
15. Grant, S.R. 1999. Dissecting the mechanisms of posttranscriptional gene silencing: divide and conquer. Cell, 96: 303-306.
16. Green, C.D., Long, K.S., Shi, H., and Wolin, S.L. 1998. Binding of the 60-kDa Ro autoantigen to Y RNAs - evidence for the recognition in the major groove of a conserved helix. RNA, 4: 750-765.
17. Hendrick, J.P., Wolin, S.L., Rinke, J., Lerner, M.R., and Steitz, J.A. 1981. Ro small cytoplasmic ribonucleoproteins are a subclass of La ribonucleoproteins: further characterization of the Ro and La small ribonucleoproteins from uninfected mammalian cells. Mol. Cell. Biol. 1: 1138-1149.
18. Huhn, P., Pruijn, G.J.M., van Venrooij, W.J., and Bachmann, M. 1997. Characterization of the autoantigen La (SS-B) as an dsRNA unwinding enzyme. Nucleic Acids Res. 25: 410-416.
19. Kelekar, A., Saitta, M.R., and Keene, J.D. 1994. Molecular composition of Ro small ribonucleoprotein complexes in human cells. Intracellular localization of the 60- and 52-kD proteins. J. Clin. Invest. 93: 1637-1644.
20. Labbé, J.-C., Jannatipour, M., and Rokeach, L.A. 1995. The Caenorhabditis elegans rop-1 gene encodes the homologue of the human 60-kDa Ro autoantigen. Gene, 167: 227-231.
21. Labbé, J.-C., Hekimi, S., and Rokeach, L.A. 1999. The levels of the RoRNP-associated Y RNA are dependent upon the presence of ROP-1, the Caenorhabditis elegans Ro60 protein. Genetics, 151: 143-150.
22. Lerner, M.R., Boyle, J.A., Hardin, J.A., and Steitz, J.A. 1981. Two novel classes of small ribonucleoproteins detected by antibodies associated with lupus erythematosus. Science (Washington, D.C.), 211: 400-402.
23. Lin-Marq, N., and Clarkson, S.G. 1998. Efficient synthesis, termination and release of RNA polymerase III transcripts in Xenopus extracts depleted of La protein. EMBO J. 17: 2033-2041.
24. Mamula, M.J., O'Brien, C.A., Harley, J.B., and Hardin, J.A. 1989. The Ro ribonucleoprotein particle: induction of autoantibodies and the detection of Ro RNAs among species. Clin. Immunol. Immunopathol. 52: 435-446.
25. Maraia, R.J. 1996. Transcription termination factor La is also an initiation factor for RNA polymerase III. Proc. Natl. Acad. Sci. U.S.A. 93: 3383-3387.
26. Maraia, R.J., Sasaki-Tozawa, N., Driscoll, C.T., Green, E.D., and Darlington, G.J. 1994. The human Y4 small cytoplasmic RNA gene is controlled by upstream elements and resides on chromosome 7 with all other hY scRNA genes. Nucleic Acids Res. 22: 3045-3052.
27. Maraia, R., Sakulich, A.L., Brinkmann, E., and Green, E.D. 1996. Gene encoding human Ro-associated autoantigen Y5 RNA. Nucleic Acids Res. 24: 3552-3559.
28. Matera, A.G., Frey, M.R., Mergelot, K., and Wolin, S.L. 1995. A perinucleolar compartment contains several RNA polymerase III transcripts as well as the polypyrimidine tract-binding protein, hnRNP I. J. Cell Biol. 129: 1181-1193.
29. Mattioli, M., and Reichlin, M. 1974. Heterogeneity of RNA protein antigens reactive with sera of patients with systemic lupus erythematosus. Description of a cytoplasmic nonribosomal antigen. Arthritis Rheum. 17: 421-429.
30. Montgomery, M.K., Xu, S.Q., and Fire, A. 1998. RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 95: 15 502-15 507.
31. O'Brien, C.A., and Harley, J.B. 1990. A subset of hY RNAs is associated with erythrocyte Ro ribonucleoproteins. EMBO J. 9: 3683-3689.
32. O'Brien, C.A., and Wolin, S.L. 1994. A possible role for the 60-kD Ro autoantigen in a discard pathway for defective 5S rRNA precursors. Genes Dev. 8: 2891-2903.
33. O'Brien, C.A., Margelot, K., and Wolin, S.L. 1993. Xenopus Ro ribonucleoproteins: members of an evolutionarily conserved class of cytoplasmic ribonucleoproteins. Proc. Natl. Acad. Sci. U.S.A. 90: 7250-7254.
34. Pannone, B.K., Xue, D.H., and Wolin, S.L. 1998. A role for the yeast La protein in U6 snRNP assembly: evidence that the La protein is a molecular chaperone for RNA polymerase III transcripts. EMBO J. 17: 7442-7453.
35. Pellizzoni, L., Cardinali, B., Linmarq, N., Mercanti, D., and Pierandreiamaldi, P. 1996. A Xenopus laevis homologue of the La autoantigen binds the pyrimidine tract of the 5′ UTR of ribosomal protein mRNAs in vitro-implication of a protein factor in complex formation. J. Mol. Biol. 259: 904-915.
36. Pellizzoni, L., Lotti, F., Rutjes, S.A., and Pierandrei-Amaldi, P. 1998. Involvement of the Xenopus laevis Ro60 autoantigen in the alternative interaction of La and CNBP proteins with the 5′UTR of L4 ribosomal protein mRNA. J. Mol. Biol. 281: 593-608.
37. Pruijn, G.J.M., Slobbe, R.L., and van Venrooij, W.J. 1991. Analysis of protein-RNA interaction within Ro ribonucleoprotein complexes. Nucleic Acids Res. 19: 5173-5180.
38. Pruijn, G.J.M., Simons, F.H.M., and van Venrooij, W.J. 1997. Intracellular localization and nucleocytoplasmic transport of Ro RNP components. Eur. J. Cell Biol. 74: 123-132.
39. Query, C.C., Bentley, R.C., and Keene, J.D. 1989. A common RNA recognition motif identified witin a defined U1 RNA binding domain of the 70K U1 snRNP protein. Cell, 57: 89-101.
40. Riddle, D.L., Blumenthal, T., Meyer, B.J., and Priess, J.R. (editors). 1997. C. elegans II. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
41. Shi, H., O'Brien, C.A., Van Horn, D.J., and Wolin, S.L. 1996. A misfolded form of 5S rRNA is complexed with the Ro and La autoantigens. RNA, 2: 769-784.
42. Simons, F.H.M., Pruijn, G.J.M., and van Venrooij, W.J. 1994. Analysis of the intracellular localization and assembly of Ro ribonucleoprotein particles by microinjection into Xenopus laevis oocytes. J. Cell Biol. 125: 981-988.
43. Simons, F.H.M., Broers, F.J.M., van Venrooij, W.J., and Pruijn, G.J.M. 1996a. Characterization of cis-acting signals for nuclear import and retention of the La (SS-B) autoantigen. Exp. Cell Res. 224: 224-236.
44. Simons, F.H.M., Rutjes, S.A., van Venrooij, W.J., and Pruijn, G.J.M. 1996b. The interaction with Ro60 and La differectially affect nuclear export of hY1 RNA. RNA, 2: 264-273.
45. Slobbe, R.L., Pluk, W., van Venrooij, W.J., and Pruijn, G.J. 1992. Ro ribonucleoprotein assembly in vitro. Identification of RNA-protein and protein-protein interactions. J. Mol. Biol. 227: 361-366.
46. Stefano, J.E. 1984. Purified lupus antigen La recognizes an oligouridylate stretch common to the 3′ termini of RNA polymerase III transcripts. Cell, 36: 145-154.
47. van Gelder, C.W.G., Thijssen, J.P.H.M., Klaassen, E.C.J., Sturchler, C., Krol, A., van Venrooij, W.J., and Pruijn, G.J.M. 1994. Common structural features of the Ro RNP associated hY1 and hY5 RNAs. Nucleic Acids Res. 22: 2498-2506.
48. Van Horn, D.J., Eisenberg, D., O'Brien, C.A., and Wolin, S.L. 1995. Caenorhabditis elegans embryos contain only one major species of Ro RNP. RNA, 1: 293-303.
49. van Venrooij, W.J., Slobbe, R.L., and Pruijn, G.J.M. 1993. Structure and function of La and Ro RNPs. Mol. Biol. Rep. 18: 113-119.
50. Wang, D.R., Buyon, J.P., and Chan, E.K.L. 1996. Cloning and expression of mouse 60 kDa ribonucleoprotein SS-A/Ro. Mol. Biol. Rep. 23: 205-210.
51. Wolin, S.L., and Steitz, J.A. 1983. Genes for two small cytoplasmic Ro RNAs are adjacent and appear to be single-copy in the human genome. Cell, 32: 735-744.
52. Wolin, S.L., and Steitz, J.A. 1984. The Ro small cytoplasmic ribonucleoproteins: Identification of the antigenic protein and its binding site on the Ro RNAs. Proc. Natl. Acad. Sci. U.S.A. 81: 1996-2000.
53. Wood, W.B., and The Community of C. elegans Researchers. 1988. The nematode Caenorhabditis elegans. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
54. Yoo, C.J., and Wolin, S.L. 1997. The yeast La protein is required for the 3′ endonucleolytic cleavage that matures tRNA precursors. Cell, 89: 393-402.
55. Zwaal, R.R., Broeks, A., van Meurs, J., Groenen, J.T.M., and Plasterk, R.H.A. 1993. Target-selected gene inactivation in Caenorhabditis elegans by using a frozen transposon insertion mutant bank. Proc. Natl. Acad. Sci. U.S.A. 90: 7431-7435.