Quantification of microvessel density of breast carcinoma: An assessment of the inter- and intraobserver variation

Breast

Volumn 8, Issue 5, 1999, Pages 251-256

  Ingeholm, P ^a   Pedersen, L ^b   Holck, S ^a  

^a HILLERØD HOSPITAL   (Denmark)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

VON WILLEBRAND FACTOR;

ANGIOGENESIS; ANTIBODY LABELING; ARTICLE; BREAST CANCER; CANCER INVASION; CAPILLAROSCOPY; CLINICAL ARTICLE; CONTROLLED STUDY; EARLY CANCER; EVALUATION; FEMALE; HUMAN; HUMAN TISSUE; MICROSCOPE; MICROVASCULATURE; OBSERVER VARIATION; PRIORITY JOURNAL; PROGNOSIS;

EID: 0032751816     PISSN: 09609776     EISSN: None     Source Type: Journal    
DOI: 10.1054/brst.1999.0057     Document Type: Article

References (51)

1. Weidner N, Weinstein R. Advances in Pathology and Laboratory Medicine. The relationship of tumor angiogenesis and metastasis with emphasis on invasive breast carcinoma. 1992;101-122 Mosby, Chicago.
2. Folkman J, Watson K, Ingber D, Hanahan D. Induction of angiogenesis during the transition from hyperplasia to neoplsia. Nature. 339:1989;58-61.
3. Mahadevan V, Hart I R. Metastasis and angiogenesis. Acta Oncol. 29:1990;97-103.
4. Bosari S, Lee A K C, De Lellis R A, Wiley B D, Heatley G J, Silverman M L. Microvessel quantitation and prognosis in invasive breast carcinoma. Human Pathol. 23:1992;755-761.
5. Brown L F, Berse B, Jackman R W. Expression of vascular permeability factor (vascular endot-helial growth factor) and its receptors in breast cancer. Human Pathol. 26:1995;86-91.
6. Bussolini F, di Renzo M F, Ziche M. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. I Cell Biol. 119:1992;629-641.
7. Schreiber A B, Winkler M E, Derynck R. Transforming growth factor- : a more potent angiogenic mediator than epidermal growth factor. Science. 232:1986;1250-1253.
8. Duffy M J, Reilly D, McDermott E, O'Higgins N, Fennelly J J, Andreasen P A. Urokinase plasminogen activator as a prognostic marker in different subgroups of patients with breast cancer. Cancer. 74:1994;2276-2280.
9. Grøndahl-Hansen J, Christensen I J, Rosenquist C. High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis. Cancer Research. 53:1993;2513-2521.
10. Jänicke F, Schmitt M, Hofter R. Urokinase-type plasminogen activator (u-PA) antigen is a predictor of early relapse in breast cancer. Fibrinolysis. 4:1990;69-78.
11. Gasparini G, Barbareschi M, Boracchi. 67-kDa laminin-receptor expression adds prognostic information to intra-tumoral microvessel density in node-negative breast cancer. Int J Cancer. 60:1995;604-610.
12. Toi M, Kashitani J, Tominaga J. Tumor angiogenesis is an independent prognostic indicator in primary breast carcinoma. Int J Cancer. 55:1993;371-374.
13. Weidner N. Tumor angiogenesis: Review of current applications in tumor prognostication. Sem Diagn Pathol. 10:1994;302-313.
14. Bigler S A, Brawer M K, Deering R E. Neovascularization in carcinoma of the prostate: a quantitative morphometric study. Mod Pathol. 5:1992;50A.
15. Wakui S, Furusato M, Itoh T. Tumor angiogenesis in prostatic carcinoma with and without bone marrow metastasis: a morphometric study. J Pathol. 168:1992;257-262.
16. Gasparini G, Weidner N, Bevilacqua P. Tumor angiogenesis and p53 protein: correlation with metastasis in head and neck squamous cell carcinoma. Int J Cancer. 55:1993;739-744.
17. Macchiarini P, Fontoini G, Hardin M J. Relation of neovasculature to metastasis of non-small-cell lung cancer. Lancet. 340:1992;145-146.
18. Bennett S, Engel C J, O'Malley F, Doig G, Chambers A. Tumor angiogenesis predicts metastasis in invasive colorectal cancer. [Abstract] Lab Invest. 1995;7257A.
19. Saclarides T J, Speziale N J, Drab E, Szeluga D J, Rubin D B. Tumor angiogenesis and rectal carcinoma. Dis Colon Rectum. 37:1994;921-926.
20. Sanz-Ortega J, Moro E, Stenberg S, Sanz-Esponera J, Merino M J. Angiogenesis as an independent prognostic factor in gastric carcinoma. [Abstract] Lab Invest. 1995;7268A.
21. Bellamy C O C, McDonald C, Salter DM, Chetty U, Andersen T J. Noninvasive ductal carcinoma of the breast: the relevance of histologic categorization. Human Pathol. 24:1993;16-23.
22. Ottesen G L, Graversen H P, Blichert-Toft M, Zedeler K, Andersen J A. Ductal carcinoma in situ of the female breast - short-term results of a prospective nationwide study. Am J Surg Pathol. 16:1992;1183-1196.
23. Bose S, Lesser M L, Norton L, Rosen P. Immunophenotype of intraductal carcinoma. Arch Pathol Lab Med. 120:1996;81-85.
24. Guidi A J, Fischer L, Harris J R, Schnitt S J. Microvessel density and distribution in ductal carcinoma in situ of the breast. J Natl Cancer Inst. 86:1994;614-619.
25. Axelsson K, Ljung B-M, Moore D. Tumor angiogenesis as a prognostic assay for invasive ductal breasr carcinoma. J Natl Cancer Inst. 87:1995;997-1008.
26. Costello P, McCann A, Carney D N, Dervan P. Lack of prognostic significance of microvessel density in lymph node negative breast carcinoma. [Abstract] Lab Invest. 1995;7216A.
27. Goulding H, Nik Abdul Rashid N F, Robertson J F. Assessment of angiogenesis in breast carcinoma. Hum Pathol. 26:1995;1196-1200.
28. Hall N R, Fish D E, Hunt N, Goldin R D, Guillou P J, Monson J R T. Is the relationship between angiogenesis and metastasis in breast cancer real? Surg Oncol. 1:1992;223-229.
29. Marley E, Frost A, Tabbara S. The significance and reproducibility of microvessel quantitation in infiltrating lobular carcinoma (ILC) of the breast. [Abstract] Lab Invest. 1995;7221A.
30. Tan L K, Lesser M L, Arroyo C D, Rosen P P. Intratumoral microcvessel density (MVD) and prognosis in breast carcinoma. [Abstract] Lab Invest. 1995;7226A.
31. van Hoef M EHM, Knox W F, Dhesi S S, Howell A, Schnor A M. Assessment of tumor vascularity as a prognostic factor in lymph node negative invasive breast cancer. Eur J Cancer. 29A:1993;1141-1145.
32. Horak E R, Leek R, Klenk N. Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as an indicator of node metastases and survival in breast cancer. Lancet. 340:1992;1120-1124.
33. Weidner N, Semple J P, Welch W R, Folkman J. Tumor angiogenesis and metastasis - correlation in invasive breast carcinoma. NEJM. 324:1991;1-8.
34. Yadrandji S, Dolan P, Visscher D W. Relationship between microvessel density and area in breast carcinomas - an image morphometric study. [Abstract]Lab Invest. 1995;7228A.
35. Gilchrist K W, Kalish L, Gould V E. Interobserver reproducibility of histopathological feature in stage II breast cancer - an ECOG study. Breast Cancer Research Treatment. 5:1985;3-10.
36. Pedersen L, Holck S, Schiødt T, Zedeler K, Mouridsen H T. Inter- and intraobserver variability in the histopathological diagnosis of medullary carcinoma of the breast, and its pro- gnostic implications. Breast Cancer Research Treatment. 14:1989;91-99.
37. Barbareschi M, Weidner N, Gasparini G. Microvessel density quantification in breast carcinoma. Assessment by light microscopy vs. a computer-aided image analysis system. Appl Immunohistochem. 3:1995;75-84.
38. De Jong J S, van Diest P J, Baak J PA. Heterogeneity of microvessel counts in breast cancer: a methodological study. [Abstract] 8th Int Symposium on diagnostic quantitative pathology. 1994;28.
39. Klijanienko J, El-Naggar A K, de Braud F. Tumor vascularization, mitotic index, histopathologic grade and DNA ploidy in the assessment of 114 head and neck squamous carcinomas. Cancer. 75:1995;1649-1656.
40. Morelli L, Barbareschi M, Gasparini G. Angiogenesis in human breast carcinoma: a comparison between human and computer assisted microvessel quantification. [Abstract] 8th Int Symposium on diagnostic quantitative pathology. 1994;29.
41. Visscher D W, Smilanetz S, Drozdowicz S. Prognostic significance of image morphometric microvessel enumeration in breast carcinoma. Analytical Quant Cytol Histol. 15:1993;88-92.
42. Miliaras D, Kamas A, Kalekou H. Angiogenesis in invasive breast carcinoma: is it associated with parameters of prognostic significance? Histopathol. 26:1995;165-169.
43. Vartanian R K, Weidner N. Correlation of intratumoral endothelial cell proliferation with microvessel density (tumour angiogenesis) and tumor cell proliferation in breast carcinoma. Am J Pathol. 114:1994;1188-1194.
44. Fox S B, Leek R, Weekes M P, Whitehouse R, Gatter K C, Harris A L. Quantitation and prognostic value of breast cancer angiogenesis: Comparison of microvessel density, Chalkley count, and computer image analysis. J Pathol. 117:1995;275-283.
45. Weidner N. Tumor angiogenesis: review of current applications in tumor prognostication. Sem Diagn Pathol. 10:1993;302-313.
46. Weidner N, Carroll P R, Flax J, Blumenfeld W, Folkman J. Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol. 143:1993;401-409.
47. Toi M, Kashitani J, Tominaga T. Tumor angiogenesis is an independent prognostic indicator in primary breast carcinoma. Int J Cancer. 55:1993;371-374.
48. Weidner N, Folkman J, Pozza F. Tumor angiogenesis: A new significant and independent prognostic indicator in early-stage breast carcinoma. J Natl Cancer Inst. 84:1992;1875-1887.
49. Vermeulen P B, Gasparini G, Fox S B. Quantification of angiogenesis in solid tumours: an international consensus on the methodology and criteria of evaluation. Eur J Cancer. 32A:1996;2474-2484.
50. van Diest P J, Baak J PA, Matze-Cok P. Reproducibility of mitosis counting in 2,469 breast cancer specimens: Results from a multicenter morphometric mammary carcinoma project. Human Pathol. 23:1992;603-607.
51. De la Torre M, Nygren P, Larsson R, Lindgren A, Tsuruo T, Bergh J. Expression of the 85-kd membrane protein in primary human breast cancer: relationship to hormone receptor levels, DNA ploidy, and tumor grade. Human Pathol. 26:1995;180-185.