A large scale synthesis of mono- and di-urethane derivatives of lysine

Chemical and Pharmaceutical Bulletin

Volumn 47, Issue 10, 1999, Pages 1489-1490

  Wiejak, Stanislaw ^a   Masiukiewicz, Elzbieta ^b   Rzeszotarska, Barbara ^b  

^a OPOLE UNIVERSITY OF TECHNOLOGY   (Poland)

^b UNIVERSITY OF OPOLE   (Poland)

Author keywords

8 quinolinol; Large scale peptide synthesis; N( ) (9 fluorenyl)methoxycarbonyl N( ) tert butoxycarbonyl L lysine; N( ) benzyloxycarbonyl N( ) tert butoxycarbonyl L lysine; N( ) tert butoxycarbonyl L lysine; N( ) tert butoxycarbonyl L lysine copper(II) complex

Indexed keywords

LYSINE DERIVATIVE; URETHAN DERIVATIVE;

ARTICLE; COMPLEX FORMATION; PEPTIDE SYNTHESIS; PROTEIN CONFORMATION; PROTEIN ISOLATION; PROTEIN MODIFICATION; PROTEIN PURIFICATION;

EID: 0032751262     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.47.1489     Document Type: Article

References (7)

1. The methods for preparing the described compounds are the object of Polish Patent Applications P 330 243, P 330 246 and P 330 245 (1998).
2. Abbreviations: Lys=lysine, Boc=tert-butoxycarbonyl, Z=benzyloxy-carbonyl, Fmoc=9-fluorenylmethoxycarbonyl, DCHA=dicyclohexylamine.
3. Gorup B., Biochem. Soc. Trans., 18, 1299-1306 (1990).
4. Scott J. W., Parker D., Parrish D. R., Synth. Comm., 11, 303-314 (1981) and references therein.
5. Atherton E., Sheppard R. C. "The Peptides. Analysis, Synthesis, Biology," Vol. 9, ed. by Udenfriend S., Meienhofer J., Academic Press, San Diego 1987, pp. 1-38.
6. Frankel M., Ladkany D., Gilon C., Wolman Y., Tetrahedron Lett., 39, 4765-4768 (1966).
7. Fields G. B., Noble R. L., Int. J. Peptide Protein Res., 35, 161-214 (1993).