Synthesis and topoisomerase inhibitory activities of novel aza-analogues of flavones

European Journal of Medicinal Chemistry

Volumn 34, Issue 5, 1999, Pages 381-387

  Sui, Zhihua ^a   Nguyen, Van N ^a   Altom, Jason ^a   Fernandez, Jeffrey ^a   Hilliard, Jamese J ^a   Bernstein, Jeffrey I ^a   Barrett, John F ^a   Ohemeng, Kwasi A ^a  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

3 hydroxy 2 phenyl 4 quinolones; Aza flavones; DNA gyrase; Topoisomerase II

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); FLAVONE DERIVATIVE;

ARTICLE; CATALYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; STRUCTURE ACTIVITY RELATION;

EID: 0032750748     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(99)80087-7     Document Type: Article

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