Correlation of cytogenetics, BCR-ABL PCR studies and fluorescence in situ hybridisation (FISH) in adult acute lymphoblastic leukaemia

Australian and New Zealand Journal of Medicine

Volumn 29, Issue 5, 1999, Pages 707-712

  Campbell, Lynda J ^a   Martinow, A ^b   Michael, P M ^a   White, J S ^a   Rayeroux, K C ^a   Januszewicz, E H ^b  

^a ST VINCENT S HOSPITAL   (Australia)

^b PETER MACCALLUM CANCER CENTRE   (Australia)

Author keywords

Acute lymphoblastic leukaemia; BCR ABL gene; FISH; Philadelphia chromosome

Indexed keywords

BCR ABL PROTEIN; MESSENGER RNA;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; AGED; ARTICLE; CANCER RECURRENCE; CYTOGENETICS; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE TRANSLOCATION; HUMAN; MALE; PHILADELPHIA 1 CHROMOSOME; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0032750467     PISSN: 00048291     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1445-5994.1999.tb01619.x     Document Type: Article

References (18)

1. 1. Secker-Walker LM, Prentice HG, Durrant J, Richards S, Hall E, Harrison G. Cytogenetics adds independent prognostic information in adults with acute lymphoblastic leukemia on MRC trial UKALL XA. Br J Haematol 1997; 96: 601-10.
2. 2. Groupe Francais de Cytogenetique Hematologique. Cytogenetic abnormalities in adult acute lymphoblastic leukemia: correlations with hematologic findings and outcome. Blood 1996; 87: 3135-42.
3. 3. Melo JV. The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype. Blood 1996; 88: 2375-84.
4. 4. Pui C-H, Crist WM, Look AT. Biology and clinical significance of cytogenetic abnormalities in childhood acute lympoblastic leukemia. Blood 1990; 76: 1449-63.
5. 5. Maurer J, Janssen JWG, Thiel E et al. Detection of chimeric BCR-ABL genes in acute lymphoblastic leukaemia by polymerase chain reaction. Lancet 1991; 337: 1055-8.
6. 6. Janssen JWG, Fonatsch C, Ludwig W-D, Reider H, Maurer J, Bartram CR. Polymerase chain reaction analysis of BCR-ABL sequences in adult Philadelphia chromosome-negative acute lymphoblastic leukemia patients. Leukemia 1992; 6: 463-4.
7. 7. Westbrook CA, Hooberman AL, Spino C et al. Clinical significance of the BCR-ABL fusion gene in adult acute lymphoblastic leukemia: a Cancer and Leukemia Group B Study. Blood 1992; 80: 2983-90.
8. 8. Radich JP, Kopecky KJ, Boldt DH et al. Detection of BCR-ABL fusion genes in adult acute lymphoblastic leukemia by the polymerase chain reaction. Leukemia 1994; 8: 1688-95.
9. 9. Devaraj PE, Foroni L, Kitra-Roussos V, Secker-Walker LM. Detection of BCR-ABL and E2A-PBX1 fusion genes by RT-PCR in acute lymphoblastic leukaemia with failed or normal cytogenetics. Br J Haematol 1995; 89: 349-55.
10. 10. Webber LM, Garson OM. Fluorodeoxyuridine synchronization of bone marrow cultures. Cancer Genet Cytogenet 1983; 8: 123-32.
11. 11. ISCN: An International System for Human Cytogenetic Nomenclature. In: Mitelman F (Ed). Basel: S. Karger, 1995.
12. 12. Dobrovic A, Trainor KJ, Morley AA. Detection of the molecular abnormality in chronic myeloid leukaemia by use of the polymerase chain reaction. Blood 1988; 72: 2063-5.
13. 13. Chase A, Grand F, Zhang J, Blackett N, Goldman J, Gordon M. Factors influencing the false positive and negative rates of BCR-ABL FISH. Genes Chromosom Cancer 1997; 18: 246-53.
14. 14. Crist W, Carroll A, Jackson J et al. Philadelphia chromosome positive childhood acute lymphoblastic leukemia: clinical and cytogenetic characteristics and treatment outcome. A pediatric oncology group study. Blood 1990; 76: 489-94.
15. 15. Gabert J, Bilhou-Nabera C, MacIntyre E et al. Prospective multicentric molecular study for poor prognosis fusion transcripts at diagnosis in adult ALL patients - an update of the LALA94 trial. Blood 1997; 90: 184a (Abstr.).
16. 16. Izraeli S, Janssen JWG, Haas OA et al. Detection and clinical relevance of genetic abnormalities in pediatric acute lymphoblastic leukemia: a comparison between cytogenetic and polymerase chain reaction analyses. Leukemia 1993; 7: 671-8.
17. 17. Hook EB. Exclusion of chromosomal mosaicism: tables of 90%, 95% and 99% confidence limits and comments on use. Am J Hum Genet 1977; 29: 94-7.
18. 18. Van Rhee F, Kasprzyk A, Jamil A et al. Detection of the BCR-ABL gene by reverse transcription/polymerase chain reaction and fluorescence in situ hybridization in a patient with Philadelphia chromosome negative acute lymphoblastic leukaemia. Br J Haematol 1995; 90: 225-8.