Non-invasive assessment of skeletal kinetics using fluorine-18 fluoride positron emission tomography: Evaluation of image and population-derived arterial input functions

European Journal of Nuclear Medicine

Volumn 26, Issue 11, 1999, Pages 1424-1429

  Cook, Gary J R ^a,b   Lodge, Martin A ^a   Marsden, Paul K ^a   Dynes, Angela ^a   Fogelman, Ignac ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b GUY S HOSPITAL   (United Kingdom)

Author keywords

Fluorine 18 fluoride; Input function; Positron emission tomography; Skeletal kinetics

Indexed keywords

FLUORODEOXYGLUCOSE F 18; TRACER;

ACCURACY; ADULT; AORTA; ARTERY; ARTICLE; BONE; BONE MINERAL; CLINICAL TRIAL; COMPARTMENT MODEL; DOSE TIME EFFECT RELATION; FEMALE; HUMAN; HUMAN EXPERIMENT; INTERMETHOD COMPARISON; INTRAVENOUS DRUG ADMINISTRATION; KINETICS; LUMBAR SPINE; MORBIDITY; NORMAL HUMAN; PLASMA CLEARANCE; POSITRON EMISSION TOMOGRAPHY; POSTMENOPAUSE; RADIAL ARTERY; REGRESSION ANALYSIS; SAMPLING; SKELETON;

FEMALE; FLUORIDES; FLUORINE RADIOISOTOPES; HUMANS; LUMBAR VERTEBRAE; MIDDLE AGED; POSTMENOPAUSE; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0032749549     PISSN: 03406997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002590050474     Document Type: Article

References (16)

1. Blau M, Nagler W, Bender MA. A new isotope for bone scanning. J Nucl Med 1962; 3: 332-334.
2. Hawkins RA, Choi Y, Huang SC, et al. Evaluation of skeletal kinetics of fluorine-18-fluoride ion with PET. J Nucl Med 1992; 33: 633-642.
3. 18F-fluoride ion in renal osteodystrophy: correlation with bone histomorphometry. J Clin Endocrinol Metab 1993; 77: 949-955.
4. Schiepers C, Nuyts J, Bormans G, et al. Fluoride kinetics of the axial skeleton measured in vivo with fluorine-18-fluoride PET. J Nucl Med 1997; 38: 1970-1976.
5. 18F]fluoride ion PET in porcine vertebrae. J Bone Miner Res 1998; 13: 1328-1336.
6. Patlak CS, Blasberg RG, Fenstenmacher JD. Graphical evaluation of blood-to-brain transfer constants from multiple time uptake data. J Cereb Blood Flow Metab 1983; 3: 1-7.
7. Al-Kutoubi A, de Jode M, Gibson M. Radial artery approach for outpatient peripheral arteriography. Clin Radiol 1996; 51: 110-112.
8. Eberl S, Anayat AR, Fulton RR, Hooper VK, Fulham MJ. Evaluation of two population-based input functions for quantitative neurological FDG PET studies. Eur J Nucl Med 1997; 24: 299-304.
9. Eriksson L, Ingvar M, Rosenqvist G, Stone-Elander S, Ekdahl T, Kappel P. Characteristics of a new automated blood sampling system for PET. IEEE Trans Nucl Sci 1995; 42: 1007-1011.
10. Ranicar ASO, Williams CW, Scnorr L, et al. The on-line monitoring of continuously withdrawn arterial blood during PET studies using a single BGO/photomultiplier assembly and non-stick tubing. Med Prog Technol 1991; 17: 259-264.
11. Wu HM, Huang SC, Schiepers C, Hoh CK. Strategy of improving noninvasive derivation of input function from dynamic PET studies [abstract]. J Nucl Med 1998; 39: 145.
12. Kato A, Menon D, Diksic M, Yamamoto YL. Influence of the input function on the calculation of the local cerebral metabolic rate for glucose in the deoxyglucose method. J Cereb Blood Flow Metab 1984; 4: 41-46.
13. Takikawa S, Dhawan V, Spetsieris P, et al. Non-invasive quantitative FDG PET studies with an estimated input function derived from a population-based arterial blood curve. Radiology 1993; 188: 131-136.
14. Wootton R, Reeve J, Veall N. The clinical measurement of skeletal blood flow. Clin Sci Mol Med 1976; 50: 261-268.
15. Fogelman I, Bessent RG, Turner JG, Citrin DL, Boyle IT, Greig WR. The use of whole body retention of Tc 99m diphosphonate in the diagnosis of metabolic bone disease. J Nucl Med 1978; 19: 270-275.
16. 18F in rabbit bone. Clin Phys Physiol Meas 1986; 7: 333-243.