Homozygotes for FRA16B are normal

Chromosome Research

Volumn 7, Issue 7, 1999, Pages 553-556

  Hocking, Trudy ^a   Feichtinger, Wolfgang ^b   Schmid, Michael ^b   Haan, Eric A ^a,c   Baker, Elizabeth ^a,c   Sutherland, Grant R ^a,c,d  

^a WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c UNIVERSITY OF ADELAIDE   (Australia)

^d UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Chromosome 16; FRA16B; Fragile sites; Homozygote

Indexed keywords

DIMINAZENE ACETURATE; FOLIC ACID;

ADULT; ARTICLE; CASE REPORT; CHROMOSOME 16; CHROMOSOME FRAGILE SITE; FEMALE; HOMOZYGOSITY; HOMOZYGOTE; HUMAN; MALE; PRIORITY JOURNAL;

ADULT; CHROMOSOME FRAGILE SITES; CHROMOSOME FRAGILITY; FEMALE; HOMOZYGOTE; HUMANS; KARYOTYPING; MALE;

EID: 0032749248     PISSN: 09673849     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1009293613064     Document Type: Article

References (9)

1. Berg JM, Faunch JA, Pendrey MJ, Penrose LS, Ridler MAC, Shapiro A (1969) A homozygous chromosomal variant. Lancet 1: 531.
2. Hewett DR, Handt O, Hobson L et al. (1998) FRA10B structure reveals common elements in repeat expansion and chromosomal fragile site genesis. Mol Cell 1: 773-781.
3. Parrish JE, Ooslra BA, Verkerk AJ et al. (1994) Isolation of a GCC repeat showing expansion in FRAXF, a fragile site distal to FRAXA and FRAXE. Nature Genet 8: 229-235.
4. Schmid M, Feichtinger W, Jessberger A, Kohler J, Lange R (1986) The fragile site 16(q22). I. Induction by AT-specific DNA-ligands and population frequency. Hum Genet 74: 67-73.
5. Sutherland GR (1981) Heritable fragile sites on human chromosomes. VII. Children homozygous for the BrdU-requiring fra(10)(q25) are phenotypically normal. Ant J Hunt Genet 33: 946-949.
6. Sutherland GR (1991) Chromosomal fragile sites. Genet Anal Techniq Applic 8: 161-167.
7. Sutherland GR, Baker E (1993) Unusual behaviour of a human autosome having two rare folate sensitive fragile sites. Ann Génét 36: 159-162.
8. Sutherland GR, Mulley JC (1996) Fragile X syndrome and other X-linked causes of mental retardation. In: Rimoin DC, Connor JM, Pyeritz RE, eds. Emery and Rimoin's Principles and Practice of Medical Genetics, 3rd Edn. Edinburgh: Churchill Livingstone, pp 1745-1766.
9. Yu S, Mangelsdorf M, Hewett D et al. (1997) Human chromosomal fragile site FRA16B is an amplified AT-rich minisatellite repeat. Cell 88: 367-374.