Chemical synthesis and structure-activity relationships of Ts κ, a novel scorpion toxin acting on apamin-sensitive SK channel

Journal of Peptide Research

Volumn 54, Issue 5, 1999, Pages 369-376

  Lecomte, Catherine ^a   Ferrat, G ^b   Fajloun, Z ^a   Van Rietschoten, J ^a   Rochat, H ^a   Martin Eauclaire, M F ^a   Darbon, H ^b   Sabatier, J M ^a  

^a CNRS   (France)

^b Centre National de la Recherche Scientifique   (France)

Author keywords

Peptide synthesis; Scorpion toxin; SK channels; Structure activity relationships; Ts

Indexed keywords

APAMIN; CALCIUM; POTASSIUM CHANNEL; TITYUS TOXIN;

ARTICLE; BRAIN SYNAPTOSOME; LETHALITY; PEPTIDE SYNTHESIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN STRUCTURE; RADIOASSAY; SCORPION; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; APAMIN; BINDING, COMPETITIVE; BRAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISULFIDES; ENDOPEPTIDASES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE FRAGMENTS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; PROTEIN BINDING; RATS; SCORPION VENOMS; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; STRUCTURE-ACTIVITY RELATIONSHIP; SYNAPTOSOMES;

SCORPIONES; TITYUS; TITYUS SERRULATUS;

EID: 0032749091     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.1999.00107.x     Document Type: Article

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