Synthesis, receptor binding and QSAR studies on 6-substituted nicotine derivatives as cholinergic ligands

European Journal of Medicinal Chemistry

Volumn 34, Issue 1, 1999, Pages 31-40

  Dukat, Malgorzata ^a   Dowd, Matthew ^a   Damaj, M Imad ^a   Martin, Billy ^a   El Zahabi, Mohamed A ^a   Glennon, Richard A ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

nAChR binding; Nicotine; Nicotinic cholinergic receptors; QSAR; Structure affinity relationships

Indexed keywords

CHOLINERGIC RECEPTOR; NICOTINE DERIVATIVE;

ARTICLE; COMPETITIVE INHIBITION; DISSOCIATION CONSTANT; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HYDROGEN BOND; LIGAND BINDING; LIPOPHILICITY; NOCICEPTION; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RECEPTOR AFFINITY;

EID: 0032748797     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(99)80038-5     Document Type: Article

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