Open field motor patterns and object marking, but not object sniffing, are altered by ibotenate lesions of the hippocampus

Neurobiology of Learning and Memory

Volumn 72, Issue 3, 1999, Pages 202-214

  Harley, C W ^a   Martin, G M ^a  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

Exploration; Neocortical lesion; Novelty; Olfaction; Open field; Orienting; Spatial map

Indexed keywords

IBOTENIC ACID;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; EXPLORATORY BEHAVIOR; HIPPOCAMPUS; LOCOMOTION; MALE; MEMORY; NEOCORTEX; NONHUMAN; OPEN FIELD BEHAVIOR; RAT; SMELLING; SNIFFING; SPATIAL ORIENTATION;

EID: 0032746966     PISSN: 10747427     EISSN: None     Source Type: Journal    
DOI: 10.1006/nlme.1998.3902     Document Type: Article

References (20)

1. Bouffard J. P., Jarrard L. E. Acquisition of a complex place task in rats with selective ibotenate lesions of hippocampal formation: Combined lesions of subiculum and entorhinal cortex versus hippocampus. Behavioral Neuroscience. 102:1988;828-834.
2. Brown R. E. Object-directed urine-marking by male rats (Rattus norwegicus). Behavioral Biology. 15:1975;251-254.
3. Cheng K. A purely geometric module in the rat's spatial representation. Cognition. 23:1968;149-178.
4. Cressant A., Muller R.U., Poucet B. Failure of centrally placed objects to control the firing fields of hippocampal place cells. Journal of Neuroscience. 17:1997;2531-2542.
5. Dimattia B. D., Kesner R. P. Spatial cognitive maps: Differential role of parietal cortex and hippocampal formation. Behavioral Neuroscience. 102:1988;471-480.
6. Dudchenko P.A., Goodridge J.P., Seiterle D.A., Taube J.S. Effects of repeated disorientation on the acquisition of spatial tasks in rats: Dissociation between the appetitive radial arm maze and aversive water maze. Journal of Experimental Psychology: Animal Behavior Processes. 23:1997;194-210.
7. Gallistel C.R. The organization of learning. 1990;MIT Press, Cambridge.
8. Glickman S. E., Higgins T.J., Isaacson R.L. Some effects of hippocampal lesions on the behavior of Mongolian gerbils. Physiology and Behavior. 5:1970;931-938.
9. Heale V. R., Vanderwolf C.H., Kavaliers M. Components of weasel and fox odors elicit fast wave bursts in the dentate gyrus of rats. Behavioural Brain Research. 63:1994;159-165.
10. Hopp S. L., Timberlake W. Odor cue determinants of urine marking in male rats (Rattus norvegicus). Behavioral and Neural Biology. 37:1983;162-172.
11. Knierim J.J., Kudrimoti H.S., McNaughton B.L. Place cells, head direction cells, and the learning of landmark stability. Journal of Neuroscience. 15:1995;1648-1659.
12. Martin G.M., Harley C.W., Smith A.R., Hoyles S., Hynes C.A. Spatial disorientation blocks reliable goal location on a plus maze but does not prevent goal location in the Morris maze. Journal of Experimental Psychology: Animal Behavior Processes. 23:1997;183-193.
13. McNaughton B.L., Barnes C.A., Gerrard J.L., Gothard K., Jung M.W., Knierim J.J., Kudrimoti H., Qin Y., Skaggs W.E., Suster M., Weaver K.L. Deciphering the hippocampal polyglot: The hippocampus as a path integration system. Journal of Experimental Biology. 199:1996;173-185.
14. Myhrer T. The role of medial and lateral hippocampal perforant path lesions and object distinctiveness in rats' reaction to novelty. Physiology and Behavior. 42:1988a;371-377.
15. Myhrer T. Exploratory behavior and reaction to novelty in rats with hippocampal perforant path systems disrupted. Behavioral Neuroscience. 102:1988b;356-362.
16. O'Keefe J., Nadel L. The hippocampus as a cognitive map. 1978;Clarendon, Oxford.
17. Otto T., Schottler F., Staubli U., Eichenbaum H., Lynch G. Hippocampus and olfactory discrimination learning: Effects of entorhinal cortex lesions on olfactory learning and memory in a successive-cue, go-no-go task. Behavioral Neuroscience. 105:1991;111-119.
18. Save E., Poucet B., Foreman N., Buhot M-C. Object exploration and reactions to spatial and nonspatial changes in hooded rats following damage to parietal cortex of hippocampal formation. Behavioral Neuroscience. 106:1992;447-456.
19. Vanderwolf C.H. Hippocampal electrical activity and voluntary movement in the rat. Electroencephalography and Clinical Neurophysiology. 26:1969;407-418.
20. Whishaw I.Q., Cassel J.-C., Jarrard L.E. Rats with fimbria-fornix lesions display a place response in a swimming pool: A dissociation between getting there and knowing where. Journal of Neuroscience. 15:1995;5779-5788.