Human renal cell cancer proliferation in tissue culture is tonically inhibited by opioid growth factor

Journal of Urology

Volumn 162, Issue 6, 1999, Pages 2186-2191

  Bisignani, Geoffrey J ^a   McLaughlin, Patricia J ^a   Ordille, Sarah D ^a   Beltz, M Scott ^a   Jarowenko, Mark V ^a   Zagon, Ian S ^a,b  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

OGF; Opioid growth factor; Renal cell cancer; Tissue culture; Met5 enkephalin

Indexed keywords

ANTIBODY; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; METENKEPHALIN; OPIATE ANTAGONIST; OPIOID GROWTH FACTOR; UNCLASSIFIED DRUG;

ARTICLE; AUTOCRINE EFFECT; CANCER CELL CULTURE; CANCER INHIBITION; CELL COUNT; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN DETERMINATION;

EID: 0032746019     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(05)68157-8     Document Type: Article

References (21)

1. Landis, S. H., Murray, T., Bolden, S. and Wingo, P. A.: Cancer statistics, 1999. CA Cancer J. Clin., 49: 8, 1999.
2. Parkin, D. M., Pisani, P. and Ferlay, J.: Global cancer statistics. CA Cancer J. Clin., 49: 33, 1999.
3. Selli, C., Hinshaw, W. M., Woodard, B. H. and Paulson, D. F.: Stratification of risk factors in renal cell carcinoma. Cancer, 52: 899, 1983.
4. Yagoda, A., Abi-Rached, B. and Petrylak, D.: Chemotherapy for advanced renal-cell carcinoma: 1983-1993. Semin. Oncol., 22: 42, 1995.
5. Haas, G.P., Hillman, G. G., Redman, B. G. and Pontes, J. E.: Immunotherapy of renal cell carcinoma. CA Cancer J. Clin., 43: 177, 1993.
6. Figlan, R. A.: Renal cell carcinoma: management of advanced disease. J. Urol., 161: 381, 1999.
7. Sporn, M. B. and Roberts, A. B. (eds.).: Peptide Growth Factors and Their Receptors I and II. Springer-Verlag:New York, 1991.
8. Steiner, M. S.: Review of peptide growth factors in benign prostatic hyperplasia and urological malignancy. J. Urol., 153: 1085, 1995.
9. Sion-Vardy, N., Vardy, D., Rodeck, U., Kari, C., Levin, R. M. and Malkowicz, B.: Antiprolierative effects of tyrosine kinase inhibitors (tryphoostins) on human bladder and renal carcinoma cells. J. Surg. Res., 59: 675, 1995.
10. Schirner, M., Hoffmann, J., Menrad, A. and Schneider, M. R.: Antiangiogenic chemotherapeutic agents: Characterization in comparison to their tumor growth inhibition in human renal cell carcinoma models. Clin. Cancer Res., 4: 1331, 1998.
11. Mydlo, J. H., Michaeli, J., Cordon-Cardo, C., Goldenberg, A. S., Heston, W. D. W. and Fair, W. R.: Expression of transforming growth factor α and epidermal growth factor receptor messenger RNA in neoplastic and nonneoplastic human kidney tissue. Cancer Res., 49: 3407, 1989.
12. Atlas, I., Mendelsohn, J., Baselga, J., Fair, W. R., Masui, H. and Kumar, R.: Growth regulation of human renal carcinoma cells: Role of transforming factor α. Cancer Res., 52: 3335, 1992.
13. Nakamoto, T., Usui, A., Oshima, K., Ikemoto, H., Mitani, S. and Usui, T.: Analysis of growth factors in renal cell carcinoma. Biochem. Biophys. Res. Comm., 153: 818, 1988.
14. Zagon, I. S. and McLaughlin, P. J.: The role of endogenous opioids and opioid receptors in human and animal cancers. In: Stress and Immunity. Edited by N. P. Plotnikoff, A. J. Murgo, R. E. Faith and J. Wybran. Caldwell, N. J.: CRC, pp. 343-356, 1991.
15. 5]-enkephalin, and the etiology, pathogenesis, and treatment of gastrointestinal cancer. In: Cytokines: Stress and Immunity. Edited by N. P. Plotnikoff, R. E. Faith, A. J. Murgo and R. A. Good. Boca Raton, FL: CRC Press, 1999.
16. 5]-enkephalin) prevents the incidence and retards the growth of human colon cancer. Am. J. Physiol., 271: R780, 1996.
17. Zagon, I. S., Hytrek, S. D., Smith, J. P. and McLaughlin, P. J.: Opioid growth factor (OGF) inhibits human pancreatic cancer transplanted into nude mice. Cancer Lett., 112: 167, 1997.
18. Zagon I. S., Hytrek S. D. and McLaughlin P. J.: Opioid growth factor tonically inhibits human colon cancer cell proliferation in tissue culture. Am. J. Physiol., 271 (Regulatory Integrative Comp. Physiol. 40): R1, 1996.
19. Zagon, I. S., Smith, J. P. and McLaughlin, P. J.: Human pancreatic cancer cell proliferation in tissue culture is tonically inhibited by opioid growth factor. Int. J. Oncol., 14: 577, 1999.
20. Fogh, J. and Trempe, G.: New human tumor cell lines. In: Human Tumor Cell Lines In Vitro. Edited by J. Jorgen. New York: Plenum Press, p. 115, 1975.
21. Naito, S., von Eschenbach, A. C., Giavazzi, R. and Fidler, I. J.: Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice. Cancer Res., 46: 4109, 1986.