Novel strategies for the design of receptor-selective vasopressin analogues: Aib-substitution and retro-inverso transformation

British Journal of Pharmacology

Volumn 128, Issue 3, 1999, Pages 647-652

  Howl, John ^a   Prochazka, Zdenko ^b   Wheatley, Mark ^c   Slaninová, Jirina ^b  

^a UNIVERSITY OF WOLVERHAMPTON   (United Kingdom)

^b INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

aminoisobutyric acid; Antagonist; Receptor subtypes; Retro inverso peptide; Vasopressin

Indexed keywords

2 AMINO 2 METHYLPROPIONIC ACID; PROTEINASE; VASOPRESSIN DERIVATIVE; VASOPRESSIN RECEPTOR; VASOPRESSIN RECEPTOR ANTAGONIST; VASOPRESSIN V1 RECEPTOR; VASOPRESSIN V2 RECEPTOR;

ANIMAL TISSUE; ANTIDIURESIS; ARTICLE; BIOASSAY; CONTROLLED STUDY; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG TRANSFORMATION; NONHUMAN; PRESSOR RESPONSE; PRIORITY JOURNAL; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINOISOBUTYRIC ACIDS; ANIMALS; ARGININE VASOPRESSIN; CATTLE; DRUG DESIGN; RATS; RECEPTORS, VASOPRESSIN;

EID: 0032744914     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702857     Document Type: Article

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