PI transfer protein: The specific recognition of phospholipids and its functions

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1441, Issue 2-3, 1999, Pages 268-277

  Sha, Bingdong ^a   Luo, Ming ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b University of Alabama at Birmingham   (United States)

Author keywords

Crystal structure; Phosphatidylcholine; Phosphatidylinositol; Sec14

Indexed keywords

CARRIER PROTEIN; PHOSPHATIDYLINOSITOL; PHOSPHOLIPID BINDING PROTEIN;

CRYSTAL STRUCTURE; HUMAN; HYDROGEN BOND; LIGAND BINDING; LIPID TRANSPORT; MEMBRANE STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; REVIEW; X RAY CRYSTALLOGRAPHY; YEAST;

ADENOSINE TRIPHOSPHATE; ANIMALS; BINDING SITES; CARRIER PROTEINS; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN BONDING; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHOSPHATIDYLINOSITOLS; PHOSPHOLIPID TRANSFER PROTEINS;

EUKARYOTA;

EID: 0032742855     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1388-1981(99)00162-6     Document Type: Review

References (17)

1. Kearns B.G., Alb J.G., Bankaitis V.A. Phosphatidylinositol transfer proteins: the long and winding road to physiological function. Trends Cell Biol. 8:1998;276-282.
2. Cockcroft S. Phosphatidylinositol transfer proteins: a requirement in signal transduction and vesicle traffic. BioEssays. 20:1998;423-432.
3. Wirtz K.W.A. Phospholipid transfer proteins revisited. Biochem. J. 324:1997;353-360.
4. Cockcroft S., Ball A., Fensome A., Hara S., Jones D., Prosser S., Swigart P. Phosphatidylinositol transfer proteins: an essential requirement in inositol lipid signaling. Biochem. Soc. Trans. 25:1997;1125-1131.
5. Skinner H.B., Alb J.G., Whitters E.A., Helmkamp G.M., Bankaitis V.A. Phospholipid transfer activity is relevant to but not sufficient for the essential function of the yeast SEC14 gene product. EMBO J. 12:1993;4775-4784.
6. Sha B., Phillips S.E., Bankaitis V.A., Luo M. Crystal structure of the S. cerevisiae phosphatidylinositol-transfer protein. Nature. 391:1998;506-510.
7. Ossendorp B.C., Snoek G.T., Wirtz K.W.A. Curr. Top. Membr. 40:1994;217-259.
8. Kader J.C. Lipid-transfer proteins in plants. Annu. Rev. Plant Physiol. Plant Mol. Biol. 47:1996;627-654.
9. Sha B., Phillips S.E., Bankaitis V.A., Luo M. Crystallization and preliminary X-ray diffraction studies of the S. cerevisiae phospholipid-transfer protein Sec14p. Acta Crystallogr. D53:1997;784-786.
10. Cleves A.E., McGee T.P., Whitters E.A., Champion K.M., Aitken J.R., Dowhan W., Goebl M., Bankaitis V.A. Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer protein. Cell. 64:1991;789-800.
11. Novick P., Field C., Schekman R. Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell. 21:1980;205-215.
12. S. Phillips, B. Sha, L. Topalof, Z. Xie, J.G. Alb, V.A. Klenchin, P. Swigart, S. Cockcroft, T.F.J. Martin, M. Luo, V.A. Bankaitis, Mol. Cell, in press.
13. Essen L., Perisic O., Cheung R., Katan M., Williams R.L. Crystal structure of a mammalian phosphoinositide-specific phospholipase C. Nature. 380:1996;595-602.
14. 2 at 2.2 Å resolution. Nature. 352:1991;79-82.
15. Lee J.Y., Min K., Cha H., Shin D.H., Hwang K.Y., Suh S.W. Rice non-specific lipid transfer protein: The 1.6 Å crystal structure in the unliganded state reveals a small hydrophobic cavity. J. Mol. Biol. 276:1998;437-448.
16. Ferguson K.M., Lemmon M.A., Schlessinger J., Sigler P. Crystal structure at 2.2Å resolution of the Pleckstrin Homology domain from human dynamin. Cell. 79:1994;199-209.
17. Fattal E., Nir S., Parente R.A., Szoka F.C. Pore-forming peptides induce rapid phospholipid flip-flop in membranes. Biochemistry. 33:1994;6721-6731.