Evidence for a separate genetic origin of the partial D phenotype DBT in a Japanese family

Transfusion

Volumn 39, Issue 11-12, 1999, Pages 1259-1265

  Huang, C H ^a   Chen, Y ^b   Reid, M E ^b   Okubo, Y ^b   Huang, Cheng Han ^b  

^a NEW YORK BLOOD CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

RHESUS D ANTIGEN;

ARTICLE; BLOOD GROUP RHESUS SYSTEM; CLINICAL ARTICLE; CODOMINANCE; CONTROLLED STUDY; FEMALE; HUMAN; IMMUNOPHENOTYPING; JAPAN; MALE; PEDIGREE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ALLELES; BASE SEQUENCE; BLOTTING, SOUTHERN; EXONS; GENE AMPLIFICATION; HEMAGGLUTINATION; HUMANS; ISOANTIGENS; JAPAN; PEDIGREE; PHENOTYPE; RECOMBINATION, GENETIC; RH-HR BLOOD-GROUP SYSTEM; TRANSCRIPTION, GENETIC;

EID: 0032742018     PISSN: 00411132     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1537-2995.1999.39111259.x     Document Type: Article

References (25)

1. Tippett P, Lomas-Francis C, Wallace M. The Rh antigen D: partial D antigens and associated low incidence antigens. Vox Sang 1996;70:123-31.
2. Jones J, Scott ML, Voak D. Monoclonal anti-D specificity and RhD structure: criteria for selection of monoclonal anti-D reagents for routine typing of patients and donors. Transfus Med 1995;5:171-84.
3. Huang CH. Molecular insights into the Rh protein family and associated antigens. Curr Opin Hematol 1997;4:94-103.
4. Cartron JP, Bailly P, Le Van Kim C, et al. Insights into the structure and function of membrane polypeptides carrying blood group antigens. Vox Sang 1998;74:29-64.
5. Wallace M, Lomas-Francis C, Beckers E, et al. DBT: a partial D phenotype associated with the low-incidence antigen Rh32. Transfus Med 1997;7:233-8.
6. N persons). Transfusion 1989;29:798-802.
7. DBT. Br J Haematol 1996;93:720-7.
8. Huang CH, Chen Y, Reid ME, Ghosh S. Genetic recombination at the human RH locus: a family study of the red-cell Evans phenotype reveals a transfer of exons 2-6 from the RHD to RHCE gene. Am J Hum Genet 1996;59:825-33.
9. Cherif-Zahar B, Raynal V, Cartron JP. Lack of RHCE-encoded proteins in the D-phenotype may result from homologous recombination between the two RH genes (letter). Blood 1996;88:1518-20.
10. Cheng GJ, Chen Y, Reid M, Huang CH. Evans antigen: a new hybrid structure occurring on background of D•• and D-Rh complexes. Vox Sang (in press).
11. Huang CH, Reid M, Chen Y. Identification of a partial internal deletion in the RH locus causing the human erythrocyte D-phenotype. Blood 1995;86:784-90.
12. W- gene complexes. Blood 1994;84:4354-60.
13. Kemp TJ, Poulter M, Carritt B. A recombination hot spot in the Rh genes revealed by analysis of unrelated donors with rare D-phenotype. Am J Hum Genet 1996;59:1066-73.
14. Huang CH, Reid ME, Chen Y, et al. Molecular definition of red cell Rh haplotypes by tightly linked Sph I RFLPs. Am J Hum Genet 1996;58:133-42.
15. W- red blood cells:phenotypic homozygosity versus genotypic heterozygosity. Blood 1996;88:2326-33.
16. Cherif-Zahar B, Bloy C, Le Van Kim C, et al. Molecular cloning and protein structure of a human blood group Rh polypeptide. Proc Natl Acad Sci U S A 1990;87:6243-7.
17. Avent ND, Ridgwell K, Tanner MJ, et al. cDNA cloning of a 30 kDa erythrocyte membrane protein associated with Rh (Rhesus)-blood-group-antigen expression. Biochem J 1990;271:821-5.
18. Le Van Kim C, Mouro I, Cherif-Zahar B, et al. Molecular cloning and primary structure of the human blood group RhD polypeptide. Proc Natl Acad Sci U S A 1992;89:10925-9.
19. null disease: the amorph type results from a novel double mutation in RhCe gene on D-negative background. Blood 1998;92:664-71.
20. w+ and Rh32+ red blood cells. Vox Sang 1998;75:230-3.
21. u), and partial D phenotypes as determined by multiplex polymerase chain reaction analysis of the RhD gene. Blood 1997;89:2568-77.
22. Wagner FF, Gassner C, Muller TH, et al. Three molecular structures cause Rhesus D category VI phenotypes with distinct immunohematologic features. Blood 1998;91:2157-68.
23. N phenotypes. Blood 1996;87:4853-61.
24. Rouillac C, Colin Y, Hughes-Jones NC, et al. Transcript analysis of D category phenotypes predicts hybrid Rh D-CE-D proteins associated with alterations of D epitopes. Blood 1995;85:2937-44.
25. Blunt T, Daniels G, Carritt B. Serotype switching in a partially deleted RHD gene. Vox Sang 1994;67:397-401.