Dimethylcarbamoyl chloride

IARC Monographs on the Evaluation of Carcinogenic Risks to Humans

Volumn 71 II, Issue , 1999, Pages 531-543

[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; CARBAMIC ACID DERIVATIVE; CARBON DIOXIDE; CHLORINE DERIVATIVE; DIMETHYLAMINE; HYDROCHLORIC ACID; WATER;

CARCINOGENICITY; CHEMICAL STRUCTURE; CONFERENCE PAPER; EVALUATION; EXPOSURE; HUMAN; NONHUMAN; NOSE CANCER; PRIORITY JOURNAL; SKIN TUMOR; TOXICITY;

ANIMALS; CARBAMATES; CARCINOGENICITY TESTS; CARCINOGENS; HUMANS; MUTAGENICITY TESTS; MUTAGENS; NEOPLASMS, EXPERIMENTAL; OCCUPATIONAL EXPOSURE; SALMONELLA TYPHIMURIUM;

EID: 0032740949     PISSN: 02509555     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (51)

1. Agrelo, C. & Amos, H. (1981) DNA repair in human fibroblasts. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 528-532
2. Anderson, D. & Styles, J.A. (1978) The bacterial mutation test. Br. J. Cancer, 37, 924-930
3. Ashby, J., Lefevre, P.A., Elliot, B.M. & Styles, J.A. (1982) An overview of the chemical and biological reactivity of 4CMB and structurally related compounds: possible relevance to the overall findings of the UKEMS 1981 study. Mutat. Res., 100, 417-433
4. Baker, R.S.U., Mitchell, K.M., Meher-Homji, K.M. & Podobna, E. (1983) Sensitivity of two Chinese hamster cell lines to SCE induction by a variety of chemical mutagens. Mutat. Res., 118, 103-116
5. Brooks, T.M. & Dean, B.J. (1981) Mutagenic activity of 42 coded compounds in the Salmonella/ microsome assay with preincubation. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 261-270
6. Dean, B.J. (1981) Activity of 27 coded compounds in the RL1 chromosome assay. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 570-579
7. Dunkel V.C., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rozenkranz, H.S. & Simmon, V.F. (1984) Reproducibility of microbial mutagenicity assays: I. Testing with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. mol. Mutag., 6, 1-254
8. Evans, E.L. & Mitchell, A.D. (1981) Effects of 20 coded chemicals on sister chromatid exchange frequencies in cultured Chinese hamster cells. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 538-550
9. Fleig, I. & Thiess, A.M. (1978) Chromosome investigations of persons exposed to dimethylcarbamoyl chloride and diethylcarbamoyl chloride. J. occup. Med., 20, 745-746
10. Foureman, P., Mason, J.M., Valencia, R. & Zimmering, S. (1994) Chemical mutagenesis testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. mol. Mutag., 23, 208-227
11. Garner, R.C., Welch A. & Pickering, C. (1981) Mutagenic activity of 42 coded compounds in the Salmonella/microsome assay. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Tern Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam Elsevier, pp. 280-284
12. Garte, S.J., Hood, A.T., Hochwalt, A.E., D'Eustachio, P., Snyder, C.A., Segal, A. & Albert, R.E. (1985) Carcinogen specificity in the activation of transforming genes by direct-acting alkylating agents. Carcinogenesis, 6, 1709-1712
13. Haworth, S., Lawlor, T., Mortelmans, K., Speck, W. & Zeiger, E. (1983) Salmonella mutagenicity test results for 250 chemicals, Environ. mol. Mutagen., 5, 3-142
14. IARC (1976) IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man, Vol. 12, Some Carbamates, Thiocarbamates and Carbazides, Lyon, pp. 77-84
15. IARC (1987) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7 Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42, Lyon, pp. 199-200
16. Jagannath, D.R., Vultaggio, D.M. & Brusick, D.J. (1981) Genetic activity of 42 coded compounds in the mitotic gene conversion assay using Saccharomyces cerevisiae strain D4. In. de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 456-467
17. Jotz, M.M. & Mitchell, A.D. (1981) Effects of 20 coded chemicals on the forward mutation frequency at the thymidine kinase locus in L5178Y mouse lymphoma cells. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the Internatinal Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 580-593
18. Kirkhart, B. (1981) Micronucleus test on 21 compounds. In: de Serres, F.J. & Ashby J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 698-704
19. Loprieno, N. (1981) Screening of coded carcinogenic/noncarcinogenic chemicals by a forward-mutation system with the yeast Schizosaccharomyces pombe. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 424-433
20. MacDonald, D.J. (1981) Salmonella/microsome tests on 42 coded chemicals. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 285-297
21. Martire, G., Vricella, G., Perfumo, A.M. & De Lorenzo, F. (1981) Evaluation of the mutagenic activity of coded compounds in the Salmonella test. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 271-279
22. Mehta, R.D. & von Borstel, R.C. (1981) Mutagenic activity of 42 encoded compounds in the haploid yeast reversion assay, strain XV185-14C. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 414-423
23. Mohn, G.R., Vogel-Bouter, S. & van der Horst-Van der Zon, J. (1981) Studies on the mutagenic activity of 20 coded compounds in liquid tests using the multipurpose strain Escherichia coli K-12/343/113 and derivatives. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 396-413
24. Nagao, M. & Takahashi, Y. (1981) Mutagenic activity of 42 coded compounds in the Salmonella/ microsome assay. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 302-313
25. Natarajan, A.T. & van Kesteren-van Leeuwen, A.C. (1981) Mutagenic activity of 20 coded compounds in chromosone aberrations/sister chromatid exchanges assay using Chinese hamster ovary (CHO) cells. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 551-559
26. Paika, I.J., Beauchesne, M.T., Randall, M., Schreck, R.R. & Latt, S.A. (1981) In vivo SCE analysis of 20 coded compounds. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 673-681
27. Parry, J.M. & Sharp, D.C. (1981) Induction of mitotic aneuploidy in the yeast strain D6 by 42 coded compounds. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 468-480
28. Perry, P.E. & Thomson, E.J. (1981) Evaluation of the sister chromatid exchange method in mammalian cells as a screening system for carcinogens. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 560-569
29. Pienta, R.J., Poiley J.A. & Lebherz, W.B., III (1977) Morphological transformation of early passage golden Syrian hamster embryo cells derived from cryopreserved primary cultures as a reliable in vitro bioassay for identifying diverse carcinogens. Int. J. Cancer, 19, 642-655
30. Probst, G.S., McMahon, R.E., Hill, L.E., Thompson, C.Z., Epp, J.K. & Neal, S.B. (1981) Chemically-induced unscheduled DNA synthesis in primary rat hepatocyte cultures: a comparison with bacterial mutagenicity using 218 compounds. Environ. mol. Mutag., 3, 11-32
31. Richold, M. & Jones, E. (1981) Mutagenic activity of 42 coded compounds in the Salmonella/microsome assay. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 314-322
32. Robinson, D.E. & Mitchell, A.D. (1981) Unscheduled DNA synthesis response of human fibroblasts, WI-38 cells, to 20 coded chemicals. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Test for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 517-527
33. Rosenkranz, H.S. & Poirier, L.A. (1979) Eavluation of the mutagenicity and DNA-modifying activity of carcinogens and noncarcinogens in microbial systems. J. natl Cancer Inst., 62, 873-892
34. Rowland, I. & Severn, B. (1981) Mutagenicity of carcinogens and noncarcinogens in the Salmonella/microsome test. In: de Serres, F.J. & Ashby, J., eds., Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elseveir, pp. 323-332
35. Salome, M.F., Heddle, J.A. & Katz, M. (1981) Mutagenic activity of 41 compounds in the in vivo micronucleus assay. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 686-697
36. Segal, A., Solomon, J.J., Mate, U. & Van Duuren, B.L. (1982) Formation of 6-dimethylcarbamyloxy-dGuo, 6-dimethylamino-dGuo and 4-dimethylamino-dThd following in vitro reaction of dimethylcarbamyl chloride with calf thymus DNA and 6-diethylcarbamyloxy-dGuo following in vitro reactionof diethylcarbamyl chloride with calf thymus DNA. Chem.-biol. Interact., 40, 209-231
37. Sellakumar, A.R., Laskin, S., Kuschmer, M., Rusch, G., Katz, G.V., Snyder, C.A. & Albert, R.E. (1980) Inhalation carcinogenesis by dimethylcarbamoyl chloride in Syrian golden hamsters. J. environ. Pathol. Toxicol., 4, 107-115
38. Sharp, D.C. & Parry, J.M. (1981a) Use of repair-deficientstrains of yeast to assay the activity of 40 coded compounds. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Test for Carcinogens. Report of the International Collaborative Program (Progressin Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 502-516
39. Sharp, D.C. & Parry, J.M. (1981b) Induction of mitotic gene conversion by 41 coded compounds using yeast culture JD1. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 491-501
40. Simmon, V.F. (1979a) In vitro mutagenicity assays of chemical carcinogens and related compounds with Salmonella typhimurium. J. natl Cancer Inst., 62, 893-899
41. Simmon, V.F. (1979b) In vitro assays for recombinogenic activity of chemical carcinogens and related compounds with Saccharomyces cerevisiae D3. J. natl Cancer Inst., 62, 901-909
42. Simmon, V.F. & Shepherd, G.F. (1981) Mutagenic activity of 42 coded compounds in the Salmonella/microsome assay. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 333-342
43. Simmon, V.F., Rozenkranz, H.S., Zeiger, E. & Poirier, L.A. (1979) Mutagenic activity of chemical carcinogens and related compounds in the intraperitoneal host-mediated assay. J. natl Cancer Inst., 62, 911-918
44. Snyder, C.A., Garte, S.J., Sellakumar, A.R. & Albert, R.E. (1986) Relationships between the levels of binding to DNA and the carcinogenic potencies in rat nasal mucosa for three alkylating agents. Cancer Lett., 33, 175-181
45. Swenberg, J.A. (1981) Utilization of the alkaline elution assay as a short-term test for chemical carcinogens. In: Stich, H.F. & San, R.H.C., eds, Short-Term Tests for Chemical Carcinogens, New York, Springer, pp. 48-58
46. Tsuchimoto, T. & Matter, B.E. (1981) Activity of coded compounds in the micronucleus test. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 705-711
47. Tweats, D.J. (1981) Activity of 42 coded compounds in a differential killing test using Eschericia coli strains WP2, WP67 (uvrA polA), and CM871 (uvrA lex A recA). In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 199-209
48. Van Duuren, B.L., Melchionne, S. & Seidman, I. (1987) Carcinogenicity of acylating agents: Chronic bioassays in mice and structure-activity relationships (SARC). J. Am. Coll. Toxicol., 6, 479-487
49. Würgler, P.E. & Graf, U. (1981) Mutagenic activity of 10 coded compounds in the Drosophila sex-linked recessive lethal assay. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 666-672
50. Yoon, J.S., Mason, J.M., Valencia, R., Woodruff, R.C. & Zimmering, S. (1985) Chemical mutagenesis testing in Drosophila. IV. Results of 45 coded compounds tested for the National Toxicology Program. Environ. Mutag., 7, 349-367
51. Zimmermann, F.K. & Scheel, I. (1981) Induction of mitotic gene conversion in strain D7 of Saccharomyces cerevisiae by 42 coded chemicals. In: de Serres, F.J. & Ashby, J., eds, Evaluation of Short-Term Tests for Carcinogens. Report of the International Collaborative Program (Progress in Mutation Research, Vol. 1), Amsterdam, Elsevier, pp. 481-490