Methyl bromide

IARC Monographs on the Evaluation of Carcinogenic Risks to Humans

Volumn 71 II, Issue , 1999, Pages 721-735

[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; METHYL BROMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; BACTERIAL MUTATION; CARCINOGENICITY; CENTRAL NERVOUS SYSTEM DISEASE; CONFERENCE PAPER; CONTROLLED STUDY; CONVULSION; DNA BINDING; EYE IRRITATION; GENE MUTATION; GLUTATHIONE METABOLISM; HUMAN; HYPOPHYSIS ADENOMA; INFECTION CONTROL; MALE; PEST CONTROL; PRIORITY JOURNAL; RAT; RESPIRATORY TRACT DISEASE; TESTIS CANCER; TREMOR;

ANIMALS; CARCINOGENICITY TESTS; CARCINOGENS; HUMANS; HYDROCARBONS, BROMINATED; MUTAGENICITY TESTS; MUTAGENS; NEOPLASMS; NEOPLASMS, EXPERIMENTAL; OCCUPATIONAL EXPOSURE;

EID: 0032740086     PISSN: 02509555     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (64)

1. American Conference of Governmental Industrial Hygienists (1992) Documentation of the Threshold Limit Values and Biological Exposure Indices, 6th Ed., Vol. 2, Cincinnati, OH, pp. 945-948
2. American Conference of Governmental Industrial Hygienists (1997) 1997 TLVs® and BEIs®, Cincinnati, OH, p. 29
3. Behrens, R.H. & Dukes, D.C.D. (1986) Fatal methyl bromide poisoning. Br. J. ind. Med., 43, 561-562
4. Bolon, B., Bonnefoi, M.S., Roberts, K.C., Marshall, M.W. & Morgan, K.T. (1991) Toxic interactions in the rat nose: pollutants from soiled bedding and methyl bromide. Toxicol. Pathol., 19, 571-579
5. Boorman, G.A., Hong, H.L., Jameson, C.W., Yoshitomi, K. & Maronpot, R.R. (1986) Regression of methyl bromide-induced forestomach lesions in the rat. Toxicol. appl. Pharmacol., 86, 131-139
6. Budavari, S., ed. (1996) The Merck Index, 12th Ed., Whitehouse Station, NJ, Merck & Co., p. 1031
7. Chemical Information Services (1995) Directory of World Chemical Producers 1995/96 Edition, Dallas, TX
8. De Haro, L., Gastaut, J.L., Jouglard, J. & Renacco, E. (1997) Central and peripheral neurotoxic effects of chronic methyl bromide intoxication. J. Toxicol. clin. Toxicol., 35, 29-34
9. Deschamps, F.J. & Turpin, J.C. (1996) Methyl bromide intoxication during grain store fumigation. Occup. Med., 46, 89-90
10. Djalali-Behzad, G., Hussain, S., Osterman-Golkar, S. & Segerbäck, D. (1981) Estimation of genetic risks of alkylating agents. VI. Exposure of mice and bacteria to methyl bromide. Mutat. Res., 84, 1-9
11. Ehrenberg, L., Osterman-Golkar, S., Singh, D. & Lundqvist, U. (1974) On the reaction kinetics and mutagenic activity of methylating and beta-halogen-ethylating gasoline additives. Radiat. Bot., 15, 185-194
12. Eustis, S.L., Haber, S.B., Drew, R.T. & Yang, R.S.H. (1988) Toxicology and pathology of methyl bromide in F344 rats and B6C3F1 mice following repeated inhalation exposure. Fundam. appl. Toxicol., 11, 594-610
13. 14C]methyl bromide. Food chem. Toxicol., 29, 557-563
14. Garnier, R., Rambourg-Schepens, M.O., Muller, A. & Hallier, E. (1996) Glutathione transferase activity and formation of macromolecular adducts in two cases of acute methyl bromide poisoning. Occup. environ. Med., 53, 211-215
15. Garry, V.F., Nelson, R.L., Griffith, J. & Harkins, M. (1990) Preparation for human study of pesticide applicators: sister chromatid exchanges and chromosome aberrations in cultured human lymphocytes exposed to selected fumigants. Teratog. Carcinog. Mutag., 10, 21-29
16. Goldman, L.R., Mengle, D., Epstein, D.M., Fredson, D., Kelly, K. & Jackson, R.J. (1987) Acute symptoms in persons residing near a field treated with the soil fumigants methyl bromide and chloropicrin. West. J. Med., 147, 95-98
17. Gotoh, K., Nishizawa, T., Yamaguchi, T., Kanou, H., Kasai, T., Ohsawa, M., Ohbayashi, H., Aiso, S., Ikawa, N., Yamamoto, S., Noguchi, T., Nagano, K., Enomoto, M., Nozaki, K. & Sakabe, H. (1994) Two-year toxicological and carcinogenesis studies of methyl bromide in F344 rats and BDF1 mice - inhalation studies. In: Sumino, K., ed., Environmental and Occupational Chemical Hazards (2): Proceedings of the Second Asia-Pacific Symposium on Environmental and Occupational Health, Singapore, Kobe University School of Medicine/National University of Singapore, pp. 185-191
18. Hallier, E., Deutschmann, S., Reichel, C., Bolt, H.M. & Peter, H. (1990) A comparative investigation of the metabolism of methyl bromide and methyl iodide in human erythrocytes. Int. Arch. occup. environ. Health, 62, 221-225
19. Hallier, E., Langhof, T., Dannappel, D., Leutbecher, M., Schröder, K.R., Goergens, H.W., Muller, A. & Bolt, H.M. (1993) Polymorphism of glutathione conjugation of methyl bromide, ethylene oxide and dichloromethane in human blood: influence on the induction of sister chromatid exchanges (SCE) in lymphocytes. Arch. Toxicol., 67, 173-178
20. Hatch, G.G., Mamay, P.D., Ayer, M.L., Casto, B.C. & Nesnow, S. (1983) Chemical enhancement of viral transformation in Syrian hamster embryo cells by gaseous and volatile chlorinated methanes and ethanes. Cancer Res., 43, 1945-1950
21. Herzstein, J. & Cullen, M.R. (1990) Methyl bromide intoxication in four field-workers during removal of soil fumigation sheets. Am. J. ind. Med., 17, 321-326
22. Hurtt, M.E. & Working, P.K. (1988) Evaluation of spermatogenesis and sperm quality in the rat following acute inhalation exposure to methyl bromide. Fundam. appl. Toxicol., 10, 490-498
23. Hurtt, M.E., Morgan, K.T. & Working, P.K. (1987) Histopathology of acute toxic responses in selected tissues from rats exposed by inhalation to methyl bromide. Fundam. appl. Toxicol., 9, 352-365
24. Hurtt, M.E., Thomas, D.A., Working, P.K., Monticello, T.M. & Morgan, K.T. (1988) Degeneration and regeneration of the olfactory epithelium following inhalation exposure to methyl bromide: pathology, cell kinetics, and olfactory function. Toxicol. appl. Pharmacol., 94, 311-328
25. Hustinx, W.N.M., van de Laar, R.T.H., van Huffelen, A.C., Verwey, J.C., Meulenbelt, J. & Savelkoul, T.J.F. (1993) Systemic effects of inhalational methyl bromide poisoning: a study of nine cases occupationally exposed due to inadvertent spread during fumigation. Br. J. ind. Med., 50, 155-159
26. IARC (1986) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 41, Some Halogenated Hydrocarbons and Pesticide Exposures, Lyon, pp. 187-212
27. IARC (1987a) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7, Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42, Lyon, pp. 245-246
28. IARC (1987b) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7, Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1-42, Lyon, pp. 321-322
29. IARC (1991) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 53, Occupational Exposures in Insecticide Application, and Some Pesticides, Lyon, pp. 179-249
30. Ikawa, N., Araki, A., Nozaki, K. & Matsushima, T. (1986) Micronucleus test of methyl bromide by the inhalation method (Abstract). Mutat. Res., 164, 269
31. International Labour Office (1991) Occupational Exposure Limits for Airborne Toxic Substances, 3rd Ed. (Occupational Safety and Health Series No. 37), Geneva, pp. 56-57
32. Iwasaki, K. (1988a) Determination of S-methylcysteine in mouse hemoglobin following exposure to methyl bromide. Ind. Health, 26, 187-190
33. Iwasaki, K. (1988b) Individual differences in the formation of hemoglobin adducts following exposure to methyl bromide. Ind. Health, 26, 257-262
34. Iwasaki, K., Ito, I. & Kagawa, J. (1989) Biological exposure monitoring of methyl bromide workers by determination of hemoglobin adducts. Ind. Health, 27, 181-183
35. Jaskot, R.H., Grose, E.C., Most, B.M., Menache, M.G., Williams, T.B. & Roycroft, J.H. (1988) The distribution and toxicological effects of inhaled methyl bromide in the rat. J. Am. Coll. Toxicol., 7, 631-635
36. JETOC (1997) Mutagenicity Test Data of Existing Chemical Substances (Based on the Toxicity Investigation System of the Industrial Safety and Health Law), Supplement, Tokyo, Japan Chemical Industry Ecology-Toxicology and Information Center, pp. 253-255
37. Kato, N., Morinobu, S. & Ishizu, S. (1986) Subacute inhalation experiment for methyl bromide in rats. Ind. Health, 24, 87-103
38. Katz, A.J. (1987) Inhalation of methyl bromide gas induces mitotic recombination in somatic cells of Drosophila melanogaster. Mutat. Res., 192, 131-135
39. Kishi, R., Itoh, I., Ishizu, S., Harabuchi, I. & Miyake, H. (1991) Symptoms among workers with long-term exposure to methyl bromide. An epidemiological study. Jpn. J. ind. Health, 33, 241-250
40. Kramers, P.G.N., Voogd, C.E., Knaap, A.G.A.C. & van der Heijden, C.A. (1985) Mutagenicity of methyl bromide in a series of short-term tests. Mutat. Res., 155, 41-47
41. Langård, S., Rognum, T., Fløtterød, Ø. & Skaug, V. (1996) Fatal accident resulting from methyl bromide poisoning after fumigation of a neighbouring house: leakage through sewage pipes. J. appl. Toxicol., 16, 445-448
42. Lewis, R.J., Jr (1993) Hawley's Condensed Chemical Dictionary, 12th Ed., New York, Van Nostrand Reinhold, p. 759
43. Lide, D.R., ed. (1997) CRC Handbook of Chemistry and Physics, 78th Ed., Boca Raton, FL, CRC Press, p. 3-205
44. Mitsumori, K., Maita, K., Kosaka, T., Miyaoka, T. & Shirasu, Y. (1990) Two-year oral chronic toxicity and carcinogenicity study in rats of diets fumigated with methyl bromide. Food chem. Toxicol., 28, 109-119
45. Moriya, M., Ohta, T., Watanabe, K., Miyazawa, T., Kato, K. & Shirasu, T. (1983) Further mutagenicity studies on pesticides in bacterial reversion assays systems. Mutat. Res., 116, 185-216
46. NOES (1997) National Occupational Exposure Survey 1981-83, Unpublished data as of November 1997, Cincinnati, OH, United States Department of Health and Human Services, Public Health Service, National Institute for Occupational Safety and Health
47. O'Neal, L. (1987) Acute methyl bromide toxicity. J. emerg. Nursing, 13, 96-98
48. Ong, T.-M., Stewart, J., Wen, Y.-F. & Whong, W.-Z. (1987) Application of SOS umu-test for the detection of genotoxic volatile chemicals and air pollutants. Environ. Mutag., 9, 171-176
49. Pemble, S., Schröder, K.R., Spencer, S.R., Meyer, D.J., Hallier, E., Bolt, H.M., Ketterer, B. & Taylor, J.B. (1994) Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism. Biochem. J., 300, 271-276
50. Polkowski, J., Crowley, M.S., Moore, A.M. & Calder, R.A. (1990) Unintentional methyl bromide gas release in Florida, 1988. Clin. Toxicol., 28, 127-130
51. Reuzel, P.G.J., Dreef-van der Meuleun, H.C., Hollanders, V.M.H., Kuper, C.F., Feron, V.J. & van der Heijden, C. (1991) Chronic inhalation toxicity and carcinogenicity study of methyl bromide in Wistar rats. Food chem. Toxicol., 29, 31-39
52. Schröder, K.R., Hallier, E., Peter, H. & Bolt, H.M. (1992) Dissociation of a new glutathione S-transferase activity in human erythrocytes. Biochem. Pharmacol., 43, 1671-1674
53. Schröder, K.R., Hallier, E., Meyer, D.J., Wiebel, F.A., Muller, A.M. & Bolt, H.M. (1996) Purification and characterization of a new glutathione S-transferase, class theta, from human erythrocytes. Arch. Toxicol., 70, 559-566
54. Sikov, M.R., Cannon, W.C., Carr, D.B., Miller, R.A., Montgomery, L.F. & Phelps, D.W. (1981) Teratologic Assessment of Butylene Oxide, Styrene Oxide and Methyl Bromide, Cincinnati, OH, United States Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Instate for Occupational Safety and Health
55. Simmon, V.F., Kauhanen, K. & Tardiff, R.G. (1977) Mutagenic activity of chemicals identified in drinking water. In: Scott, D., Bridges, B.A. & Sobels, F.H., eds, Progress in Genetic Toxicology, Amsterdam, Elsevier/North-Holland, pp. 249-258
56. Starratt, A.N. & Bond, E.J. (1988) In vitro methylation of DNA by the fumigant methyl bromide. J. environ. Sci. Health, B23, 513-525
57. Tucker, J.D., Xu, J., Stewart, J., Baciu, P.C. & Ong, T.-M. (1986) Detection of sister chromatid exchanges induced by volatile genotoxicants. Teratog. Carcinog. Mutag., 6, 15-21
58. United States National Library of Medicine (1997) Hazardous Substances Data Bank (HSDB), Bethesda, MD [Record No. 779]
59. 1 Mice (Inhalation Studies) (NTP TR 385; NIH Publ. No. 92-2840), Research Triangle Park, NC
60. WHO (1993) Guidelines for Drinking Water Quality, 2nd Ed., Vol. 1, Recommendations, Geneva
61. WHO (1995) Methyl Bromide (Environmental Health Criteria 166), Geneva, International Programme on Chemical Safety
62. Wong, O., Brocker, W., Davis, H.V. & Nagle, G.S. (1984) Mortality of workers potentially exposed to organic and inorganic brominated chemicals, DBCP, TRIS, PBB, and DDT. Br. J. ind. Med., 41, 15-24
63. Yang, R.S.H., Witt, K.L., Alden, C.J. & Cockerham, L.G. (1995) Toxicology of methyl bromide. Rev. environ. Contam. Toxicol., 142, 65-85
64. Zwaveling, J.H., de Kort, W.L.A.M., Meulenbelt, J., Hezemans-Boer, M., van Vloten, W.A. & Sangster, B. (1987) Exposure of the skin to methyl bromide: a study of six cases occupationally exposed to high concentrations during fumigation. Hum. Toxicol., 6, 491-495