메뉴 건너뛰기




Volumn 277, Issue 5 40-5, 1999, Pages

Influence of obesity and body fat distribution on growth hormone kinetics in humans

Author keywords

Clearance; Distribution volume; Fat distribution; Fat mass; Somatotropin

Indexed keywords

GROWTH HORMONE; HUMAN GROWTH HORMONE; SOMATOSTATIN;

EID: 0032739365     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1999.277.5.e824     Document Type: Article
Times cited : (34)

References (42)
  • 2
    • 0023150078 scopus 로고
    • The effect of circulating growth hormone-binding protein on metabolic clearance, distribution, and degradation of human growth hormone
    • Baumann, G., K. Amburn, and T. A. Buchanan. The effect of circulating growth hormone-binding protein on metabolic clearance, distribution, and degradation of human growth hormone. J. Clin. Endocrinol. Metab. 64: 657-660, 1987.
    • (1987) J. Clin. Endocrinol. Metab. , vol.64 , pp. 657-660
    • Baumann, G.1    Amburn, K.2    Buchanan, T.A.3
  • 3
    • 0020540864 scopus 로고
    • The molecular nature of circulating growth hormone in normal and acromegalic man: Evidence for a principle and minor monomeric forms
    • Baumann, G., J. G. MacGart, and K. Amburn. The molecular nature of circulating growth hormone in normal and acromegalic man: evidence for a principle and minor monomeric forms. J. Clin. Endocrinol. Metab. 56: 946-952, 1983.
    • (1983) J. Clin. Endocrinol. Metab. , vol.56 , pp. 946-952
    • Baumann, G.1    MacGart, J.G.2    Amburn, K.3
  • 4
    • 0027762639 scopus 로고
    • Growth hormone-binding proteins in plasma
    • Baumann, G., and M. Mercado. Growth hormone-binding proteins in plasma. Nutrition 9: 546-553, 1993.
    • (1993) Nutrition , vol.9 , pp. 546-553
    • Baumann, G.1    Mercado, M.2
  • 5
    • 0025274067 scopus 로고
    • A second, lower affinity growth hormone-binding protein in human plasma
    • Baumann, G., and M. A. Shaw. A second, lower affinity growth hormone-binding protein in human plasma. J. Clin. Endocrinol. Metab. 70: 680-686, 1990.
    • (1990) J. Clin. Endocrinol. Metab. , vol.70 , pp. 680-686
    • Baumann, G.1    Shaw, M.A.2
  • 7
    • 0026733019 scopus 로고
    • Effect of long term rhGH administration in GH-deficient adults on fat cell epinephrine response
    • Endocrinol. Metab. 26
    • Beauville, M., I. Harant, F. Crampes, D. Riviere, M. T. Tauber, J. P. Tauber, and M. Garrigues. Effect of long term rhGH administration in GH-deficient adults on fat cell epinephrine response. Am. J. Physiol. 263 (Endocrinol. Metab. 26): E467-E472, 1992.
    • (1992) Am. J. Physiol. , vol.263
    • Beauville, M.1    Harant, I.2    Crampes, F.3    Riviere, D.4    Tauber, M.T.5    Tauber, J.P.6    Garrigues, M.7
  • 8
    • 0343683306 scopus 로고    scopus 로고
    • Body fat distribution, insulin resistance, and metabolic diseases
    • Bjorntorp, P. Body fat distribution, insulin resistance, and metabolic diseases. Nutrition 13: 795-803, 1997.
    • (1997) Nutrition , vol.13 , pp. 795-803
    • Bjorntorp, P.1
  • 9
    • 0023629587 scopus 로고
    • Influence of obesity on drug disposition
    • Blouin, R. A., J. H. Kolpek, and H. J. Mann. Influence of obesity on drug disposition. Clin. Pharmacol. 6: 706-714, 1987.
    • (1987) Clin. Pharmacol. , vol.6 , pp. 706-714
    • Blouin, R.A.1    Kolpek, J.H.2    Mann, H.J.3
  • 10
    • 0024562684 scopus 로고
    • In-vivo uptake of human growth hormone in male rat liver
    • Bullier-Picard, F., M. C. Postel-Vinay, and C. Kayser. In-vivo uptake of human growth hormone in male rat liver. J. Endocrinol. 121: 19-25, 1989.
    • (1989) J. Endocrinol. , vol.121 , pp. 19-25
    • Bullier-Picard, F.1    Postel-Vinay, M.C.2    Kayser, C.3
  • 12
    • 0026738993 scopus 로고
    • Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men
    • Corpas, E., S. M. Harman, M. A. Pineyro, R. Roberson, and M. R. Blackman. Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men. J. Clin. Endocrinol. Metab. 75: 530-535, 1992.
    • (1992) J. Clin. Endocrinol. Metab. , vol.75 , pp. 530-535
    • Corpas, E.1    Harman, S.M.2    Pineyro, M.A.3    Roberson, R.4    Blackman, M.R.5
  • 13
    • 0025973547 scopus 로고
    • Growth hormone treatment in growth hormone-deficient adults. I. Effects on muscle mass and strength
    • Cuneo, R. C., F. Salomon, C. M. Wiles, R. Hesp, and P. H. Sonksen. Growth hormone treatment in growth hormone-deficient adults. I. Effects on muscle mass and strength. J. Appl. Physiol. 70: 688-694, 1991.
    • (1991) J. Appl. Physiol. , vol.70 , pp. 688-694
    • Cuneo, R.C.1    Salomon, F.2    Wiles, C.M.3    Hesp, R.4    Sonksen, P.H.5
  • 14
    • 0028944463 scopus 로고
    • Clinical aspects of growth hormone deficiency in adults
    • De Boer, H., G. J. Blok, and E. A. van der Veen. Clinical aspects of growth hormone deficiency in adults. Endocr. Rev. 16: 63-86, 1995.
    • (1995) Endocr. Rev. , vol.16 , pp. 63-86
    • De Boer, H.1    Blok, G.J.2    Van Der Veen, E.A.3
  • 15
    • 0023804376 scopus 로고
    • Metabolic clearance rates of synthetic human growth hormone in lean and obese male rhesus monkeys
    • Dubey, A. K., A. Hanukoglu, B. C. Hansen, and A. A. Kowarski. Metabolic clearance rates of synthetic human growth hormone in lean and obese male rhesus monkeys. J. Clin. Endocrinol. Metab. 67: 1064-1067, 1988.
    • (1988) J. Clin. Endocrinol. Metab. , vol.67 , pp. 1064-1067
    • Dubey, A.K.1    Hanukoglu, A.2    Hansen, B.C.3    Kowarski, A.A.4
  • 16
    • 0024598777 scopus 로고
    • Half-time of endogenous growth hormone (GH) disappearance in normal man after stimulation of GH secretion by GH-releasing hormone and suppression with somatostatin
    • Faria, A. C., J. D. Veldhuis, M. O. Thorner, and M. L. Vance. Half-time of endogenous growth hormone (GH) disappearance in normal man after stimulation of GH secretion by GH-releasing hormone and suppression with somatostatin. J. Clin. Endocrinol. Metab. 68: 535-541, 1989.
    • (1989) J. Clin. Endocrinol. Metab. , vol.68 , pp. 535-541
    • Faria, A.C.1    Veldhuis, J.D.2    Thorner, M.O.3    Vance, M.L.4
  • 18
    • 0028220465 scopus 로고
    • Metabolic clearance of recombinant human growth hormone in health and chronic renal failure
    • Haffner, D., F. Schaefer, J. Girard, E. Ritz, and O. Mehis. Metabolic clearance of recombinant human growth hormone in health and chronic renal failure. J. Clin. Invest. 93: 1163-1171, 1994.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1163-1171
    • Haffner, D.1    Schaefer, F.2    Girard, J.3    Ritz, E.4    Mehis, O.5
  • 19
    • 0028294357 scopus 로고
    • Renal and cardiovascular mechanisms of hypertension in obesity
    • Hall, J. E. Renal and cardiovascular mechanisms of hypertension in obesity. Hypertension 23: 381-394, 1994.
    • (1994) Hypertension , vol.23 , pp. 381-394
    • Hall, J.E.1
  • 20
    • 0022457186 scopus 로고
    • Identification and characterization of specific binding proteins for growth hormone in normal human sera
    • Herington, A. C., S. I. Ymer, and J. L. Stevenson. Identification and characterization of specific binding proteins for growth hormone in normal human sera. J. Clin. Invest. 77: 1817-1823, 1986.
    • (1986) J. Clin. Invest. , vol.77 , pp. 1817-1823
    • Herington, A.C.1    Ymer, S.I.2    Stevenson, J.L.3
  • 21
    • 0026570421 scopus 로고
    • The distal axis of growth hormone (GH) in nutritional disorders: GH-binding protein, insulin-like growth factor-I (IGF-I), and IGF-I receptors in obesity and anorexia nervosa
    • Hochberg, Z., P. Hertz, V. Colin, S. Ish-Shalom, D. Yeshurun, M. B. Youdim, and T. Amit. The distal axis of growth hormone (GH) in nutritional disorders: GH-binding protein, insulin-like growth factor-I (IGF-I), and IGF-I receptors in obesity and anorexia nervosa. Metabolism 41: 106-112, 1992.
    • (1992) Metabolism , vol.41 , pp. 106-112
    • Hochberg, Z.1    Hertz, P.2    Colin, V.3    Ish-Shalom, S.4    Yeshurun, D.5    Youdim, M.B.6    Amit, T.7
  • 22
    • 0028323084 scopus 로고
    • Sensitivity and specificity of the Quetelet index to assess obesity in men and women
    • Hortobagyi, T., R. G. Israel, and K. F. O'Brien. Sensitivity and specificity of the Quetelet index to assess obesity in men and women. Eur. J. Clin. Nutr. 48: 369-375, 1994.
    • (1994) Eur. J. Clin. Nutr. , vol.48 , pp. 369-375
    • Hortobagyi, T.1    Israel, R.G.2    O'Brien, K.F.3
  • 23
    • 0023714041 scopus 로고
    • Receptor-mediated endocytosis and degradation of bovine growth hormone in rat liver
    • Husman, B., J. A. Gustafson, and G. Andersson. Receptor-mediated endocytosis and degradation of bovine growth hormone in rat liver. Mol. Cell. Endocrinol. 59: 13-25, 1988.
    • (1988) Mol. Cell. Endocrinol. , vol.59 , pp. 13-25
    • Husman, B.1    Gustafson, J.A.2    Andersson, G.3
  • 24
    • 0025787687 scopus 로고
    • Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous GH in healthy men
    • Iranmanesh, A., G. Lizarralde, and J. D. Veldhuis. Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous GH in healthy men. J. Clin. Endocrinol. Metab. 73: 1081-1088, 1991.
    • (1991) J. Clin. Endocrinol. Metab. , vol.73 , pp. 1081-1088
    • Iranmanesh, A.1    Lizarralde, G.2    Veldhuis, J.D.3
  • 26
    • 0023488498 scopus 로고
    • Methods for the assessment of human body composition: Traditional and new
    • Lukaski, H. C. Methods for the assessment of human body composition: traditional and new. Am. J. Clin. Nutr. 46: 537-556, 1987.
    • (1987) Am. J. Clin. Nutr. , vol.46 , pp. 537-556
    • Lukaski, H.C.1
  • 27
    • 0029150551 scopus 로고
    • Nutritional status and growth hormone-binding protein
    • Postel-Vinay, M. C., C. Saab, and M. Gourmelen. Nutritional status and growth hormone-binding protein. Horm. Res. 44: 177-181, 1995.
    • (1995) Horm. Res. , vol.44 , pp. 177-181
    • Postel-Vinay, M.C.1    Saab, C.2    Gourmelen, M.3
  • 28
    • 0019558598 scopus 로고
    • Removal and excretion of immunoreactive rat growth hormone by the isolated kidney
    • Renal Fluid Electrolyte Physiol. 9
    • Rabkin, R., T. I. Gottheiner, and V. S. Fang. Removal and excretion of immunoreactive rat growth hormone by the isolated kidney. Am. J. Physiol. 240 (Renal Fluid Electrolyte Physiol. 9): F282-F287, 1981.
    • (1981) Am. J. Physiol. , vol.240
    • Rabkin, R.1    Gottheiner, T.I.2    Fang, V.S.3
  • 29
    • 0029964173 scopus 로고    scopus 로고
    • Serum growth hormone-binding protein in obesity: Effect of a short-term, very low calorie diet and diet induced weight loss
    • Rasmussen, M. H., K. K. Ho, L. L. Kjems, and J. Hilsted. Serum growth hormone-binding protein in obesity: effect of a short-term, very low calorie diet and diet induced weight loss. J. Clin. Endocrinol. Metab. 81: 1519-1524, 1996.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 1519-1524
    • Rasmussen, M.H.1    Ho, K.K.2    Kjems, L.L.3    Hilsted, J.4
  • 30
    • 0028953083 scopus 로고
    • Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects
    • Rasmussen, M. H., A. Hvidberg, A. Anders, K. M. Main, A. Gotfredsen, N. E. Skakkebaek, and J. Hilsted. Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects. J. Clin. Endocrinol. Metab. 80: 1407-1415, 1995.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 1407-1415
    • Rasmussen, M.H.1    Hvidberg, A.2    Anders, A.3    Main, K.M.4    Gotfredsen, A.5    Skakkebaek, N.E.6    Hilsted, J.7
  • 31
    • 0026598346 scopus 로고
    • A method for measuring binding affinity and capacity of growth hormone binding protein in human serum using FPLC to separate bound and free ligand
    • Roelen, C. A. M., G. H. Donker, J. H. H. Thijssen, and M. A. Blankenstein. A method for measuring binding affinity and capacity of growth hormone binding protein in human serum using FPLC to separate bound and free ligand. J. Liq. Chromatog. 15: 1259-1275, 1992.
    • (1992) J. Liq. Chromatog. , vol.15 , pp. 1259-1275
    • Roelen, C.A.M.1    Donker, G.H.2    Thijssen, J.H.H.3    Blankenstein, M.A.4
  • 33
    • 0029760162 scopus 로고    scopus 로고
    • Applications of bioelectrical impedance analysis for body composition to epidemiologic studies
    • Roubenoff, R. Applications of bioelectrical impedance analysis for body composition to epidemiologic studies. Am. J. Clin. Nutr. 64, Suppl: 459S-462S, 1996.
    • (1996) Am. J. Clin. Nutr. , vol.64 , Issue.SUPPL.
    • Roubenoff, R.1
  • 34
    • 0029044371 scopus 로고
    • Predicting body fatness: The body mass index vs. estimation by bioelectrical impedance
    • Roubenoff, R., G. E. Dallal, and P. W. Wilson. Predicting body fatness: the body mass index vs. estimation by bioelectrical impedance. Am. J. Public Health 85: 726-728, 1995.
    • (1995) Am. J. Public Health , vol.85 , pp. 726-728
    • Roubenoff, R.1    Dallal, G.E.2    Wilson, P.W.3
  • 35
    • 0023203357 scopus 로고
    • Processing of growth hormone by rat adipocytes in primary culture: Differentiation between release of intact hormone and degradative processing
    • Roupas, P., and A. C. Herington. Processing of growth hormone by rat adipocytes in primary culture: differentiation between release of intact hormone and degradative processing. Endocrinology 121: 1521-1530, 1987.
    • (1987) Endocrinology , vol.121 , pp. 1521-1530
    • Roupas, P.1    Herington, A.C.2
  • 37
    • 0024854194 scopus 로고
    • The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency
    • Salomon, F., R. C. Cuneo, R. Hesp, and P. H. Sonksen. The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N. Engl. J. Med. 321: 1797-1803, 1989.
    • (1989) N. Engl. J. Med. , vol.321 , pp. 1797-1803
    • Salomon, F.1    Cuneo, R.C.2    Hesp, R.3    Sonksen, P.H.4
  • 38
    • 0030060620 scopus 로고    scopus 로고
    • Multifactorial control of the elimination kinetics of unbound (free) growth hormone (GH) in the human: Regulation by age, adiposity, renal function, and steady state concentrations of GH in plasma
    • Schaefer, F., G. Baumann, D. Haffner, L. M. Faunt, M. L. Johnson, M. Mercado, E. Ritz, O. Mehls, and J. D. Veldhuis. Multifactorial control of the elimination kinetics of unbound (free) growth hormone (GH) in the human: regulation by age, adiposity, renal function, and steady state concentrations of GH in plasma. J. Clin. Endocrinol. Metab. 81: 22-31, 1996.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 22-31
    • Schaefer, F.1    Baumann, G.2    Haffner, D.3    Faunt, L.M.4    Johnson, M.L.5    Mercado, M.6    Ritz, E.7    Mehls, O.8    Veldhuis, J.D.9
  • 39
    • 0019381758 scopus 로고
    • Effect of somatostatin on splanchnic hemodynamics in patients with cirrhosis of the liver and in normal subjects
    • Sonnenberg, G. E., U. Keller, A. Perruchoud, A. Burkhardt, and K. Gyr. Effect of somatostatin on splanchnic hemodynamics in patients with cirrhosis of the liver and in normal subjects. Gastroenterology 80: 526-532, 1981.
    • (1981) Gastroenterology , vol.80 , pp. 526-532
    • Sonnenberg, G.E.1    Keller, U.2    Perruchoud, A.3    Burkhardt, A.4    Gyr, K.5
  • 40
    • 0030737928 scopus 로고    scopus 로고
    • Abdominal adiposity rather than age and sex predicts mass and regularity of GH secretion in healthy adults
    • Endocrinol. Metab. 35
    • Vahl, N., J. O. L. Jørgensen, C. Skjærbæk, J. D. Veldhuis, H. Orskov, and J. S. Christiansen. Abdominal adiposity rather than age and sex predicts mass and regularity of GH secretion in healthy adults. Am. J. Physiol. 272 (Endocrinol. Metab. 35): E1108-E1116, 1997.
    • (1997) Am. J. Physiol. , vol.272
    • Vahl, N.1    Jørgensen, J.O.L.2    Skjærbæk, C.3    Veldhuis, J.D.4    Orskov, H.5    Christiansen, J.S.6
  • 41
  • 42
    • 0027473686 scopus 로고
    • Influence of the high-affinity growth hormone (GH)-binding protein on plasma profiles of free and bound GH and on the apparent half-life of GH
    • Veldhuis, J. D., M. L. Johnson, L. M. Faunt, M. Mercado, and G. Baumann. Influence of the high-affinity growth hormone (GH)-binding protein on plasma profiles of free and bound GH and on the apparent half-life of GH. J. Clin. Invest. 91: 629-641, 1993.
    • (1993) J. Clin. Invest. , vol.91 , pp. 629-641
    • Veldhuis, J.D.1    Johnson, M.L.2    Faunt, L.M.3    Mercado, M.4    Baumann, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.