Catecholaminergic activity and 3',5'-cyclic adenosine monophosphate concentrations in the right ventricle after acute and chronic morphine administration in the rat

British Journal of Anaesthesia

Volumn 83, Issue 5, 1999, Pages 784-788

  Milanes M V ^a   Fuente, T ^b   Marin M T ^c   Laorden, M L ^a  

^a UNIVERSITY OF MURCIA   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DE LA ARRIXACA   (Spain)

^c Microbial Exopolysaccharide Research Group   (Spain)

Author keywords

Analgesics opioid, morphine; Heart, ventricles; Metabolism, cAMP; Potency, drug, tolerance; Rat; Sympathetic nervous system, dopamine; Sympathetic nervous system, norepinephrine

Indexed keywords

CATECHOLAMINE DERIVATIVE; CYCLIC AMP; DOPAMINE; MORPHINE; NORADRENALIN; NORMETADRENALIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATECHOLAMINE METABOLISM; CONTROLLED STUDY; HEART RIGHT VENTRICLE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MORPHINE TOLERANCE; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT;

EID: 0032737949     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/83.5.784     Document Type: Article

References (33)

1. Holaday JW. Cardiovascular effects of endogenous opiate system. Annu Rev Pharmacol Toxicol 1983; 23: 541-94
2. Weihe E, McKnight AT, Corbbet AD, Kosterlitz HW. Proenkephalin-and prodynorphin-derived pioid peptides in guinea-pig heart. Neuropeptides 1985; 5: 453-6
3. Wegener A, Kunmer W. Sympathetic noradrenergic fibers as the source of immunoreactive alpha-neoendorphin and dynorphin in the guinea-pig heart. Acta Anat 1994; 151: 112-19
4. Jin WQ, Tai KK, Chau TK, Wong TM. Further characterization of [3H]U69593 binding sites in the rat heart. J Mol Cell Cardiol 1995; 27: 1507-11
5. Steele PA, Aromatais EC, Riederer BM. Endogenous opioid peptides parasympathetic and sensory nerves in the guinea-pig heart. Cell Tissue Res 1996; 284: 331-9
6. Witter G, Hope P, Pile D. Tissue distribution of opioid receptor gene expression in the rat. Biophys Res Commun 1996; 218:877-81
7. Nestler EJ, Hope BT, Widnell KL Drug addiction: a model for molecular basis of neural plasticity. Neuron 1993; 11: 995-1006
8. Guitart X, Thompson MA, Mirante CK, Greenberg ME, Nestler EJ. Regulation of cyclic AMP response element-binding protein (CREB) phosphorylation by acute and chronic morphine in the tar locus coeruleus. J Neurochem 1992; 58: 1168-71
9. Nestler E, Aghajanianm GK. Molecular and cellular basis of addiction. Science 1997; 278: 58-63
10. Self DW, Nestler EJ. Molecular mechanisms of drug reinforcement and addiction. Annu Rev Neurosci 1995; 18: 463-95
11. Nestler EJ. Molecular mechanisms of drug reinforcement and addiction. J Neurosci 1992; 12: 2450-93
12. Xia Q, Sheng JZ, Tai KK, Wong TM. Effects of chronic U-50,488H treatment on binding and mechanical responses of the rat hearts. J Pharmacol Exp Ther 1994; 268: 930-4
13. Rabadán JV, Milanés MV, Laorden ML. Effects of acute administration of morphine or right atrial catecholamine content and heart rate in chronically morphine-treated rats. Br J Anaesth 1997; 78: 439-41
14. Rabadán JV, Milanés MV, Laorden ML. Effects of chronic morphine treatment on catecholamine content and mechanical response in the rat heart. J Pharmacol Exp Ther 1997; 280: 32-7
15. Gonzálvez ML, Milanés MV, Martínez-Piñero MG, Marĩn MT, Vargas ML. Effects of intracerebroventricular clonidine on the hypothalamic noradrenaline and plasma corticosterone levels of opiate naïve rats and after naloxone-induced withdrawal. Brain Res 1994; 647: 199-203
16. Garaulet JV, Laorden ML, Milanés MV. Cross-tolerance between mu-and kappa-opioid agonists in the guinea pig ileum myenteric plexus. J Pharmacol Exp Ther 1994; 269: 993-9
17. Rabadán JV, Milanés MV, Laorden ML. Changes in right atria catecholamine content in naïve rats and after naloxone-induced withdrawal. Br J Anaesth 1998; 80: 354-9
18. Vargas ML, Martínez-Piñero MG, Milanés MV. Neurochemical activity of noradrenergic neurons and pituitary-adrenal response after naloxone-induced withdrawal: the role of calcium channels. Naunyn Schmiedebergs Arch Pharmacol 1997; 355: 501-6
19. Olson GA, Olson RD, Kasting, AJ. Endogenous opiates: 1993. Peptides 1994; 15: 1513-56
20. Tallarida RJ, Murray RB. Pharmacologic Calculations, 2nd Edn. New York: Springer Verlag, 1987
21. Elayan H, Kennedy B, Zieglel MG. Propranolol reduces rat dopamine β-hydroxylase activity and catecholamine levels. Eur J Pharmacol 1992; 212: 259-62
22. Kujacic M, Hansson LO, Carlsson A. Acute dopaminergic influence on plasma adrenaline levels in the rat. Eur J Pharmacol 1995; 273: 247-57
23. 4 receptor: sequence, gene structure, and demonstration of expression in the cardiovascular system. New Biol 1992; 4: 137-46
24. Ozono R, O'Connell DP, Vaughan C, et al. Expression of the subtype IA dopamine receptor in the rat heart. Hypertension 1996; 27: 693-703
25. Childers SR. Opioid receptor-coupled second messenger systems. Life Sci 1991; 48: 1991-2003
26. Sharma SK, Klee WA, Nirenberg M, Klee A. Morphine receptors as regulators of adenylate cyclase activity. Proc Natl Acad Sci USA 1975; 72: 590-4
27. Sharma SK, Klee WA, Nirenberg M, Klee A. Opiate-dependent modulation of adenylate cyclase. Proc Natl Acad Sci USA 1977; 74: 3365-9
28. Attali B, Saya D, Vogel Z. Kappa-opiate agonists inhibit adenylate cyclase and produce heterologous desensitization in rat spinal cord. J Neurochem 1989; 52: 360-9
29. McKenczie FR, Milligan D. Delta-opioid-receptor-mediated inhibition of adenylate cyclase is transduced specifically by the guanine-nucleotide-binding protein Gi2. Biochem J 1990: 267: 391-8
30. 1-13 on cardiac rhythm and cyclic adenosine monophosphate (cAMP) levels in the isolated perfused rat heart. Nature 1977; 267: 495-9
31. Pepe S, Xiao RP, Hohl C, Atschuld E, Lakatta EG. 'Cross talk' between opioid peptide and adrenergic receptor signaling in isolated rat heart. Circulation 1997; 95: 2122-9
32. Maldonado R, Blendy JA, Tzavara E, et al. Reduction of morphine abstinence in mice with a mutation in the gene enconding CREB. Science 1996; 273: 657-9
33. Selley DE, Nestler EJ, Breivogel CS, Childers SR. Opioid receptor-coupled G-proteins in rat locus coeruleus membranes: decrease in activity after chronic morphine treatment. Brain Res 1997; 746: 10-18