Multiple logistic regression analysis of plasma paraquat concentrations as a predictor of outcome in 375 cases of paraquat poisoning

QJM: An International Journal of Medicine

Volumn 92, Issue 10, 1999, Pages 573-578

  Jones, A L ^a   Elton, R ^b   Flanagan, R ^a  

^a GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHARCOAL; PARAQUAT;

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD LEVEL; CHILD; DISEASE COURSE; FEMALE; HEMODIALYSIS; HEMOPERFUSION; HUMAN; LUNG TOXICITY; MAJOR CLINICAL STUDY; MALE; MATHEMATICAL MODEL; NEPHROTOXICITY; PARAQUAT POISONING; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; REGRESSION ANALYSIS;

EID: 0032737936     PISSN: 00335622     EISSN: None     Source Type: Journal    
DOI: 10.1093/qjmed/92.10.573     Document Type: Article

References (65)

1. Jeyaratnam J. Acute pesticide poisoning: a major global health problem. World Health Stat Q 1990; 43:139-44.
2. Thompson JP, Casey PB, Vale JA. Deaths from pesticide poisoning in England and Wales 1990-1991. Hum Exp Toxicol 1995; 14:437-45.
3. Proudfoot AT, Stewart MS, Levitt T, Widdop, B. Paraquat poisoning: significance of plasma-paraquat concentrations. Lancet 1979; 2:330-2.
4. Van de Vyver FL, Giuliano RA, Paulus GJ, Verpooten GA, Franke JP, de Zeeuw RA, van Gaal LF, De Broe ME. Hemoperfusion-hemodialysis ineffective for paraquat removal in life-threatening poisoning. J Toxicol Clin Toxicol 1985; 23:117-31.
5. HargreaveTB, Gresham GA, Karayannopoulos S. Paraquat poisoning. Postgrad Med J 1969; 45:633-5.
6. Malone JDG, Carmody M, Keogh B, O'Dwyer WF. Paraquat poisoning - a review of nineteen cases. J Irish Med Assoc 1971; 64:59-68.
7. Davidson JK, MacPherson P. Pulmonary changes in paraquat poisoning. Clin Radiol 1972; 23:18-25.
8. Douglas JF, McGeown MG, McEvoy J. The treatment of paraquat poisoning: three cases of recovery. Ulster Med J 1973; 42:209-12.
9. Eliahou HE, Almog C, Gura V, Iaina A. Treatment of paraquat poisoning by hemodialysis. Isr J Med Sci 1973; 9:459-62.
10. Okonek S, Hofmann A, Henningsen B. Efficacy of gut lavage, hemodialysis, and hemoperfusion in the therapy of paraquat or diquat intoxication. Arch Toxicol 1976; 36:43-51.
11. Sofrank G, Mathes GV, Clarmann M, Beyer KH. Haemoperfusion through activated charcoal in paraquat intoxication. Acta Pharmacol Toxicol (Copenh) 1977; 41:91-101.
12. Vale JA, Crome P, Volans GN, Widdop B, Goulding R. The treatment of paraquat poisoning using oral sorbents and charcoal haemoperfusion. Acta Pharmacol Toxicol (Copenh) 1977; 41:109-17.
13. Ackrill P, Hasleton PS, Ralston AJ. Oesophageal perforation due to paraquat. Br Med J 1978; 1:1252-3.
14. Dearnaley DP, Martin MFR. Plasmapheresis for paraquat poisoning. Lancet 1978; 1:162.
15. Spector D, Whorton D, Zachary J, Slavin R. Fatal paraquat poisoning: tissue concentrations and implications for treatment. Johns Hopkins Med J 1978; 142:110-13.
16. Fairshter RD, Dabir-Vaziri N, Smith WR, Glauser FL, Wilson AF. Paraquat poisoning: an analytical toxicologic study of three cases. Toxicology 1979; 12:259-66.
17. Higenbottam T, Crome P, Parkinson C, Nunn J. Further clinical observations on the pulmonary effects of paraquat ingestion. Thorax 1979; 34:161-5.
18. Rose JD. Paraquat poisoning (letter). Lancet 1980; 2:924.
19. Russell LA, Stone BE, Rooney PA. Paraquat poisoning: toxicologic and pathologic findings in three fatal cases. Clin Toxicol 1981; 18:915-28.
20. Vincken W, Huyghens L, Schandevyl W, Verbeelen D, Corne L. Paraquat poisoning and colchicine treatment (letter). Ann Intern Med 1981; 95:391-2.
21. Bismuth C, Gamier R, Dally S, Fournier PE. Prognosis and treatment of paraquat poisoning: a review of 28 cases. J Toxicol Clin Toxicol 1982; 19:461-74.
22. De Groot G. Haemoperfusion in paraquat intoxication. In: Haemoperfusion in Clinical Toxicology. A Pharmacokinetic Evaluation, Vol. 1. Utrecht, These, 1982.
23. Mofenson HC, Greensher J, Caraccio TR, Agostino R. Paraquat intoxication: report of a fatal case. Discussion of pathophysiology and rational treatment. J Toxicol Clin Toxicol 1982; 19:821-34.
24. Musson FA, Porter CA. Effect of ingestion of paraquat on a 20-week gestation fetus. Postgrad Med J 1982; 58:731-2.
25. Siefkin AD. Combined paraquat and acetaminophen toxicity. J Toxicol Clin Toxicol 1982; 19:483-91.
26. Garnier R, Efthymiou ML, Baud F. Haemoperfusion for paraquat poisoning. Lancet 1983; ii:277.
27. Hoffman S, Jedeikin R, Korzets Z, Shapiro A, Kaplan R, Bernheim J. Successful management of severe paraquat poisoning. Chest 1983; 84:107-9.
28. Mascie-Taylor BH, Thompson J, Davison AM. Haemoperfusion ineffective for paraquat removal in life-threatening poisoning. Lancet 1983; 1:1376-7.
29. Scherrman JM, Galliot M, Garnier R, Bismuth C. Acute paraquat poisoning: prognostic significance and therapeutic interest of blood assay. Toxicol Eur Res 1983; 5:141-5.
30. Van de Vyver FL, van de Sande J, Verpooten GA, De Broe ME, van den Heede M, Heyndrickx A. Haemoperfusion ineffective for paraquat removal in life-threatening poisoning. Lancet 1983; 2:1376-7.
31. Hendy MS, Williams PS, Ackrill P. Recovery from severe pulmonary damage due to paraquat administered intravenously and orally. Thorax 1984; 39:874-5.
32. Webb DB, Williams MV, Davies BH, James KW. Resolution after radiotherapy of severe pulmonary damage due to paraquat poisoning. Br Med J 1984; 288:1259.
33. Addo E, Poon King T. Leucocyte suppression in treatment of 72 patients with paraquat poisoning. Lancet 1986; 1:1117-20.
34. Bismuth C, Baud F, Dally S. Standardised prognosis evaluation in acute toxicology its benefit in colchicine, paraquat and digitalis poisonings. J Toxicol Clin Exp 1986; 6:33-8.
35. Yasaka T, Okufddaira K, Fujito H, Atsumoto J, Ohya I, Miyamoto Y. Further studies of lipid peroxidation in human paraquat poisoning. Arch Intern Med 1986; 146:681-5.
36. Ikebuchi J. Evaluation of paraquat concentrations in paraquat poisoning. Arch Toxicol 1987; 60:304-10.
37. Pond SM, Johnston SC, Schoof DD, Hampson EC, Bowles M, Wright DM, Petrie JJ. Repeated hemoperfusion and continuous arteriovenous hemofiltration in a paraquat poisoned patient. J Toxicol Clin Toxicol 1987; 25:305-16.
38. Scherrman JM, Houze P, Bismuth C, Bourdon R. Prognostic value of plasma and urine paraquat concentration. Hum Toxicol 1987; 6:91-3.
39. Williams MV, Webb DB. Paraquat lung is there a role for radiotherapy? Hum Toxicol 1987; 6:75-81.
40. Baud FJ, Houze P, Bismuth C, Scherrman J, Jaeger A, Keyes C. Toxicokinetics of paraquat through the heart-lung block. Six cases of acute human poisoning. J Toxicol Clin Toxicol 1988; 26:35-50.
41. Hampson ECGM, Pond SM. Failure of haemoperfusion and haemodialysis to prevent death in paraquat poisoning. A retrospective review of 42 patients. Med Toxicol 1988; 3:64-71.
42. Sawada Y, Yamamoto I, Hirokane T, Nagai Y, Satoh Y, Ueyama M. Severity index of paraquat poisoning. Lancet 1988; 1:1333.
43. Talbot AR, Barnes MR. Radiotherapy for the treatment of pulmonary complications of paraquat poisoning. Hum Toxicol 1988; 7:325-32.
44. Talbot AR, Fu CC, Hsieh MF. Paraquat intoxication during pregnancy: a report of 9 cases. Vet Hum Toxicol 1988; 30:12-17.
45. Hoffer E, Taitelman U. Exposure to paraquat through skin absorption: clinical and laboratory observations of accidental splashing on healthy skin of agricultural workers. Hum Toxicol 1989; 8:483-5.
46. Suzuki K, Takasu N, Arita S, Maenosono A, Ishimatsu S, Nishina M, Tanaka S, Kohama A. A new method for predicting the outcome and survival period in paraquat poisoning. Hum Toxicol 1989; 8:33-8.
47. Franzen D, Baer F, Heitz W, Mecking H, Eidt S, Käferstein H, Baldamus CA, Curtius JM, Höpp HW, Wassermann K. Failure of radiotherapy to resolve fatal lung damage due to paraquat poisoning. Chest 1991; 100:1164-5.
48. Ragoucy-Sengler C, Pileire B, Daijardin JB. Survival from severe paraquat intoxication in heavy drinkers. Lancet 1991; 338:1461.
49. Suzuki K, Nobukatsu T, Arita S, Ueda A, Okabe T, Ishimatsu S, Tanaka S, Kohama A. Evaluation of severity indexes of patients with paraquat poisoning. Hum Exp Toxicol 1991; 10:21-3.
50. Florkowski CM, Bradberry SM, Ching GWK, Jones AF. Acute renal failure in a case of paraquat poisoning with relative absence of pulmonary toxicity. Postgrad Med J 1992; 68:660-2.
51. Perriens JH, Benimadho S, Kiauw IL, Wisse J, Chee H. High-dose cyclophosphamide and dexamethasone in paraquat poisoning: a prospective study. Hum Exp Toxicol 1992; 11:129-34.
52. Rivero C, Martinez R, Gonzalez E, Espinoza OB, Ramirez MS. Paraquat poisoning in children: survival of three cases. Vet Hum Toxicol 1992; 34:164-5.
53. Suzuki K, Takasu N, Okabe T, Ishimatsu S, Ueda A, Tanaka S, Fukuda A, Arita S, Kohama A. Effect of aggressive haemoperfusion on the clinical course of patients with paraquat poisoning. Hum Exp Toxicol 1993; 12:323-7.
54. Casey PB, Buckley BM, Vale JA. Methemoglobinemia following ingestion of a monolinuron/paraquat herbicide (Gramanol). Clin Toxicol 1994; 32:185-9.
55. Garnier R, Chataigner D, Efthymiou M, Moraillon I, Bramary F. Paraquat poisoning by skin absorption: report of two cases. Vet Hum Toxicol 1994; 36:313-15.
56. Koppel C, Wissmann CV, Barckow D, Rossaint R, Falke K, Stoltenburg-Didinger G, Schnoy N. Inhaled nitric oxide in advanced paraquat intoxication. Clin Toxicol 1994; 32:205-14.
57. Lheureux P, Leduc D, Vanbinst R, Askenasi R. Survival in a case of massive paraquat ingestion. Chest 1995; 107:285-9.
58. Hart TB, Nevitt A, Whitehead A. A new statistical approach to the prognostic significance of plasma paraquat concentration. Lancet 1984; 1:1222.
59. Yamaguchi H, Sato S, Watanabe S, Naito H. Pre-embarkment prognostication for acute paraquat poisoning. Hum Exp Toxicol 1990; 9:381-4.
60. Kaojarern S, Ongphiphadhanakul B. Predicting outcomes in paraquat poisonings. Vet Hum Toxicol 1991; 33:115-18.
61. Ikebuchi J, Proudfoot AT, Matsubara K, Hampson ECGM, Tomita M, Suzuki K, Fuke C, Ijiri I, Tsunerari T, Yuasa I, Okada K. Toxicological index of paraquat: a new strategy for assessment of severity of paraquat poisoning in 128 patients. Forens Sci Int 1993; 59:85-7.
62. Berry DJ, Grove J. The determination of paraquat cation in urine. Clin Chim Acta 1971; 34:5-11.
63. Meredith TJ, Vale JA. Treatment of paraquat poisoning in man Methods to prevent absorption. Hum Toxicol 1987; 6:49-55.
64. Honoré P, Hantson P, Fauville JP, Peeters A, Manieu P. Paraquat poisoning. 'State of the art'. Acta Clin Belg 1994; 49:220-8.
65. Proudfoot AT, Prescott LF, Jarvie DR. Haemodialysis for paraquat poisoning. Hum Toxicol 1987; 6:69-74.