Molecular defects in variant forms of mannose-binding protein associated with immunodeficiency

Journal of Immunology

Volumn 163, Issue 9, 1999, Pages 4953-4959

  Wallis, Russell ^a   Cheng, Jason Y T ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MANNOSE BINDING PROTEIN; OLIGOMER;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; COMPLEMENT FIXATION; CONTROLLED STUDY; GENE DISRUPTION; GENE LOSS; GENETIC ANALYSIS; IMMUNE DEFICIENCY; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN PROCESSING;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ARGININE; ASPARTIC ACID; CARRIER PROTEINS; COLLECTINS; COMPLEMENT FIXATION TESTS; CYSTEINE; DISULFIDES; GLUTAMIC ACID; GLYCINE; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; MANNANS; MOLECULAR SEQUENCE DATA; POINT MUTATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS;

EID: 0032736419     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Turner, M. W. 1996. Mannose-binding lectin: the pluripotent molecule of the innate immune system. Immunol. Today 17:532.
2. Weis, W. I., M. E. Taylor, and K. Drickamer. 1998. The C-type lectin superfamily in the immune system. Immunol. Rev. 163:19.
3. Ikeda, K., T. Sannoh, N. Kawasaki, T. Kawasaki, and I. Yamashina. 1987. Serum lectin with known structure activates complement through the classical pathway. J. Biol. Chem. 262:7451.
4. Super, M., R. J. Levinsky, and M. W. Turner. 1990. The level of mannan-binding protein regulates the binding of complement-derived opsonins to mannan and zymosan at low serum concentrations. Clin. Exp. Immunol. 79:144.
5. Drickamer, K., and M. E. Taylor. 1993. Biology of animal lectins. Annu. Rev. Cell Biol. 9:237.
6. Matsushita, M., and T. Fujita. 1992. Activation of the classical complement pathway by mannose-binding protein in association with a novel Cls-like serine protease. J. Exp. Med. 176:1497.
7. Takahashi, A., Y. Takayama, H. Hatsuse, and M. Kawakami. 1993. Presence of a serine protease in the complement-activating component of the complement-dependent bactericidal factor, RaRF, in mouse serum. Biochem. Biophys. Res. Commun. 190:681.
8. Thiel, S., T. Vorup-Jensen, C. M. Stover, W. Schwaeble, S. B. Laursen, K. Poulsen, A. C. Willis, P. Eggleton, S. Hansen, U. Holmskov, K. B. M. Reid, and J. C. Jensenius. 1997. A second serine protease associated with mannan-binding lectin that activates complement. Nature 386:506.
9. Reid, K. B. M. 1983. Proteins involved in the activation and control of the two pathways of human complement. Biochem. Soc. Trans. II:1.
10. Super, M., S. Thiel, J. Lu, R. J. Levinsky, and M. W. Turner. 1989. Association of low levels of mannan-binding protein with a common defect of opsonization. Lancet 2:1236.
11. Sumiya, M., M. Super, P. Tabona, R. J. Levinsky, A. Takayuki, M. W. Turner, and J. A. Summerfield. 1991. Molecular basis of opsonic defect in immunodeficient children. Lancet 337:1569.
12. Garred, P., H. O. Madsen, U. Balslev, B. Hofmann, C. Pedersen, J. Gerstoft, and A. Svejgaard. 1997. Susceptibility to HIV infection and progression of AIDS in relation to varient alleles of mannose-binding lectin. Lancet 349:236.
13. Madsen, H. O., P. Garred, J. A. Kurtzhals, L. U. Lamm, L. P. Ryder, S. Thiel, and A. Svejgaard. 1994. A new frequent allele is the missing link in the structural polymorphism of the human mannan-binding protein. Immunogenetics 40:37.
14. Lipscombe, R. J., M. Sumiya, J. A. Summerfield, and M. W. Turner. 1995. Distinct physicochemical characteristics of human mannose binding protein expressed by individuals of differing genotype. Immunology 85:660.
15. Lipscombe, R. J., M. Sumiya, A. V. S. Hill, Y. L. Lau, R. J. Levinsky, J. A. Summerfield, and M. W. Turner. 1992. High frequencies in African and non-African populations of independent mutations in the mannose binding protein gene. Hum. Mol. Genet. 1:709.
16. Madsen, H. O., P. Garred, S. Thiel, J. A. Kurtzhals, L. U. Lamm, L. P. Ryder, and A. Svejgaard. 1995. Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein. J. Immunol. 155:3013.
17. Wallis, R., and K. Drickamer. 1997. Asymmetry adjacent to the collagen-like domain in rat liver mannose-binding protein. Biochem. J. 325:391.
18. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680.
19. Maniatis, T., E. F. Fritsch, and J. Sambrook. (1982) Molecular Cloning: a Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
20. Wallis, R., and K. Drickamer. 1999. Molecular determinants of oligomer formation and complement fixation in mannose-binding proteins. J. Biol. Chem. 274: 3580.
21. Taylor, M. E., P. M. Brickell, R. K. Craig,and J. A. Summerfield. 1989. Structure and evolutionary origin of the gene encoding a human serum mannose-binding protein. Biochem. J. 262:763.
22. Drickamer, K., M. S. Dordal, and L. Reynolds. 1986. Mannose-binding proteins isolated from rat liver contain carbohydrate-recognition domains linked to collagenous tails. J. Biol. Chem. 261:6878.
23. Kadler, K. 1994. Extracellular matrix. I. Fibril-forming collagens. Protein Profile 1:519.
24. Vogel, B. E., R. Doelz, K. E. Kadler, Y. Hojima, J. Engel, and D. J. Prockop. 1988. A substitution of cysteine for glycine 748 of the α 1 chain produces a kink at this site in the procollagen I molecule and an altered N-proteinase cleavage site over 225 nm away. J. Biol. Chem. 263:19249.
25. Lightfoot, S. J., D. F. Holmes, A. Brass, M. E. Grant, P. H. Byers, and K. E. Kadler. 1994. Type I procollagens containing substitutions of aspartate. arginine, and cysteine for glycine in the pro α1 (I) chain are cleaved slowly by N-proteinase, but only the cysteine substitution introduces a kink in the molecule. J. Biol. Chem. 267:25521.
26. Baum, J., and B. Brodsky. 1999. Folding of peptide models of collagen and misfolding in disease. Curr. Opin. Struct. Biol. 9:122.
27. Super, M., S. D. Gillies, S. Foley, K., Sastry, J.-E. Schweinle, V. J. Silverman, and R. A. B. Ezekowitz. 1992. Distinct and overlapping function of allelic forms of human mannose binding protein. Nat. Genet. 2:50.
28. Kurata, H., H. M. Cheng, Y. Kozutsumi, Y. Yokota, and T. Kawasaki. 1993. Role of the collagen-like domain of the human serum mannan-binding protein in the activation of complement and the secretion of this lectin. Biochem. Biophys. Res. Commun. 191:1204.
29. Matsushita, M., R. A. Ezekowitz, and T. Fujita. 1995. The Gly54→Asp allelic form of human mannose-binding protein (MBP) fails to bind MBP-associated serine prolease. Biochem. J. 311:1021.