Serum levels of beta-2-microglobulin-free heavy chain of HLA class I antigen in healthy individuals: Relationship to their class I allotype

Human Immunology

Volumn 60, Issue 11, 1999, Pages 1058-1066

  Perosa, Federico ^a   Prete, Marcella ^a   Luccarelli, Grazia ^a   Favoino, Biagio ^b   Ferrone, Soldano ^c   Dammacco, Franco ^a  

^a Dept Biomed Sci and Hum Oncol   (Italy)

^b UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

^c ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; HLA ANTIGEN CLASS 1;

ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HLA SYSTEM; HUMAN; HUMAN CELL; IMMUNOBLOTTING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL;

ALLELES; ANIMALS; ANTIBODIES, MONOCLONAL; BETA 2-MICROGLOBULIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; MICE; REFERENCE STANDARDS; SOLUBILITY;

EID: 0032736417     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(99)00081-6     Document Type: Article

References (32)

1. Ploegh H.L., Orr H.T., Strominger J.L. Major histocompatibility antigens the human (HLA-A, -B, -C) and murine (H-2K, H-2D) class 1 molecules . Cell. 24:1981;287.
2. van Rood J.J., van Leeuwen A., van Santem M.C.T. Anti-HLA-A2 inhibitor in normal human sera. Nature. 226:1970;366.
3. Puppo F., Scudeletti M., Indiveri F., Ferrone S. Serum HLA class 1 antigens markers and modulators of an immune response? Immunol Today. 16:1995;124.
4. Forman D. Serum β2-microglobulin as an indicator of neoplasia. J Clin Immunoassay. 37:1993;1140.
5. Nocito M., Montalbán C., Gonzále-Porque P., Villar L.M. Increased soluble serum HLA class 1 antigens in patients with lymphoma. Hum Immunol. 58:1997;106.
6. Aulitzky W.E., Grosse-Wilde H., Westhoff U., Tilg H., Aulitzky W., Gastl G., Herold M., Huber C. Enhanced serum levels of soluble HLA class 1 molecules are induced by treatment with recombinant interferon-gamma (IFN-γ). Clin Exp Immunol. 86:1991;236.
7. Alvarez-Cermeño J.C., Casado C., Villar L.M. Soluble class 1 antigens (sHLA) in CSF and serum of patients with HIV infections. Acta Neurol Scand. 82:1990;14.
8. Bhalla R.B., Safai B., Mertelsmann M.K. Abnormally high concentrations of β2-microglobulin in acquired immunodeficiency syndrome (AIDS) patients. Clin Chem. 29:1983;1560.
9. Fahey J.L., Taylor J.M.G., Detels R., Hofmann B., Melmed R., Nishanian P., Giorgi J.V. The prognostic value of cellular and serological markers in infection with human immunodeficiency virus type. I. N Engl J Med. 322:1990;166.
10. Davies H., Pollard S.G., Calne R.Y. Soluble HLA antigens in the circulation of liver graft recipients. Transplantation. 47:1989;524.
11. Zavazava N., Bottcher H., Muller-Ruchholtz W. Soluble MHC class 1 antigens (sHLA) and anti-HLA antibodies in heart and kidney allograft recipients. Tissue Antigens. 42:1993;20.
12. Puppo F., Brenci S., Lanza L., Bosco O., Imro M.A., Scudeletti M., Indiveri F., Ferrone S. Increased level of serum HLA class 1 antigens in HIV infection. Correlation with disease progression. Human Immunol. 40:1994;259.
13. Wolf R.E., Adamashvilli I.M., Gelder F.B., Hall V.C., Fraser P.A., McDonald J.C. Soluble HLA-I in rheumatic diseases. Hum Immunol. 59:1998;644.
14. Kao K.J., Scornik J.C., Riley W.J., McQueen C.F. Association between HLA phenotype and HLA concentration in plasma and platelets. Hum Immunol. 21:1988;115.
15. Doxiadis I., Westhoff U., Grosse-Wilde H. Quantification of soluble HLA class 1 gene products by an enzyme linked immunosorbent assay. Blut. 59:1989;449.
16. Pickl W.F., Majdic O., Faé I., Reuschel R., Holter W., Knapp W. The soluble pool of β2-microglobulin free HLA class 1 α-chains. Qualitative and quantitative characterization. J Immunol. 151:1993;2613.
17. Bresciani A., Pirozzi G., Spera M., Lombardi M.L., Ambrosone L., Migliaresi S., Ferrone S., Manzo C. Increased level of serum HLA class 1 antigens in patients with systemic lupus erythematosus. Correlation with disease activity. Tissues Antigens. 52:1998;44.
18. Hiraki D.D., See-Tho K., Filvaroff E., Krishnaswanny S., de Bello W., Taidi-Laskowski B., Grumet F.C. Bioengineered soluble HLA B7. Genesis, characterization and occurrence of dimerization. Hum Immunol. 40:1994;235.
19. Hamby C.V., Kageshita T., Wang Z., Liang B., Temponi M., Ferrone S. Analysis of αν/β3 integrin expression by cultured human melanoma cells. Hori Y., Hearing V.J., Nakayama J. Melanogenesis and Malignant Melanoma Biochemistry, Cell Biology, Molecular Biology, Pathophysiology, Diagnosis and Treatment . 1996;Elsevier Science, Amsterdam.
20. Pellegrino M.A., Ng A.K., Russo C., Glassy M., Ferrone S. Immunochemical analysis of anti-HLA-A2, HLA-A3, and HLA-B27 xenoantisera elicited with hybrids between human and murine cells. Immunogenetics. 14:1981;141.
21. Stam N.J., Spits H., Ploegh H.L. Monoclonal antibodies raised against denatured HLA-B locus heavy chain permit biochemical characterization of certain HLA-C locus products. J Immunol. 137:1986;2299.
22. Tanabe M., Sekimata M., Ferrone S., Taniguchi M. Structural and functional analysis of monomorphic determinants recognized by monoclonal antibodies reacting with the HLA class 1 alpha 3 domain. J Immunol. 148:1992;2302.
23. D'urso C.M., Wang Z.G., Cao Y., Tatake R., Zeff R.A., Ferrone S. Lack of HLA class 1 antigen expression by cultured melanoma cells FO-1 due to a defect in β2m gene expression. J Clin Invest. 87:1991;284.
24. th International Histocompatibility Workshop and Conference II. 1992;393 Oxford University Press.
25. Laemmly U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680.
26. Perosa F., Carbone R., Ferrone S., Dammacco F. Purification of human immunoglobulins by sequential precipitation with caprylic acid and ammonium sulphate. J Immunol Methods. 128:1990;9.
27. Streicher H.Z., Cuttitta F., Buckenmeyer G.K., Kawamura H., Minna J., Berzofsky J.A. Mapping of the idiotopes of a monoclonal anti-myoglobin antibody with syngeneic monoclonal anti-idiotypic antibodies detection of a common idiotope . J Immunol. 136:1986;1007.
28. Perosa F., Rizzi R., Pulpito V., Dammacco F. Soluble CD4 antigen reactivity in intravenous immunoglobulin preparations is it specific? Clin Exp Immunol. 99:1995;16.
29. Kao J. Plasma and platelet HLA in normal individuals quantitation by competitive enzyme linked immunoassay . Blood. 70:1987;282.
30. Adamashvili I.M., Fraser P.A., McDonald J.C. Association of serum concentrations of soluble class 1 HLA with allotypes. Transplantation. 61:1996;984.
31. Demaria S., Gottesman S.R., Bushkin Y. Soluble beta 2-microglobulin-free class 1 heavy chains are released from the surface of activated and leukemia cells by a metalloproteinase. J Biol Chem. 269:1994;6689.
32. DeVito-Haynes L.D., Demaria S., Bushkin Y., Burlingham W.J. The metalloproteinase-mediated pathway is essential for generation of soluble HLA class 1 proteins by activated cells in vitro proposed mechanism for soluble HLA release in transplant rejection . Hum Immunol. 59:1998;426.