Effect of cytoplasmic tail truncations on the activity of the M2 ion channel of influenza A virus

Journal of Virology

Volumn 73, Issue 12, 1999, Pages 9695-9701

  Tobler, Kurt ^a   Kelly, Marie L ^b   Pinto, Lawrence H ^b   Lamb, Robert A ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ION CHANNEL;

ARTICLE; INFLUENZA VIRUS A; ION CONDUCTANCE; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; STOP CODON; VIRUS REPLICATION;

EID: 0032736043     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.12.9695-9701.1999     Document Type: Article

References (49)

1. 2 ion channel protein: probing the structure of the transmembrane domain in intact cells by using engineered disulfide cross-linking. Virology 254:195-209.
2. 2 protein. J. Virol. 69:2725-2728.
3. 2 channel expressed in mouse erythroleukaemia cells. J. Physiol. 494:329-336.
4. 2-mediated conversion of influenza A virus hemagglutinin to the low pH conformation occurs in an acidic trans Golgi compartment. Virology 188:14-24.
5. 2 protein forms amantadine-sensitive proton channels in planar lipid bilayers. Virology 190:485-489.
6. 2 ion channel. Virology 202:287-293.
7. 2 transmembrane domain. FEBS Lett. 311: 256-258.
8. Flinta, C., B. Persson, H. Jornvall, and G. von Heijne. 1986. Sequence determinants of cytosolic N-terminal protein processing. Eur. J. Biochem. 154:193-196.
9. 2 channel domain: verification by comparison. Fold Design. 3:443-448.
10. + channel by C-terminal truncation of the bovine subunit. J. Biol. Chem. 271:26602-26608.
11. 2 protein. J. Biol. Chem. 274:5474-5482.
12. 2 channel activity. FEBS Lett. 357:269-274.
13. 2 protein. Virology 190:11-18.
14. 2 ion channel protein. Semin. Virol. 3:21-30.
15. Hay, A. J., A. J. Wolstenhohne, J. J. Skehel, and M. H. Smith. 1985. The molecular basis of the specific anti-influenza action of amantadine. EMBO J. 4:3021-3024.
16. 2 integral membrane protein is a homotetramer stabilized by formation of disulfide bonds. Virology 183:32-43.
17. 2 ion channel protein: a structure-function analysis. J. Virol. 68:1551-1563.
18. 2 protein. J. Virol. 69:1219-1225.
19. + channels. J. Neurosci. 14:1385-1393.
20. Hoshi, T., W. N. Zagotta, and R. W. Aldrich. 1990. Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science 250:533-538.
21. + channels: effects of alterations in the carboxy-terminal region. Neuron 7:547-556.
22. + channel inactivation mediated by the concerted action of the cytoplasmic N- and C-terminal domains. Biophys. J. 72:163-174.
23. 2 protein channel: structural implications from helix tilt and orientation. Biophys. J. 73:2511-2517.
24. + channel. J. Mol. Biol. 286:951-962.
25. 2 ion channel protein and its role in the influenza virus life cycle, p. 303-321. In E. Wimmer (ed.), Receptor-mediated virus entry into cells. Cold Spring Harbor Press, Cold Spring Harbor, N.Y.
26. Lamb, R. A., C.-J. Lai, and P. W. Choppin. 1981. Sequences of mRNAs derived from genome RNA segment 7 of influenza virus: colinear and interrupted mRNAs code for overlapping proteins. Proc. Natl. Acad. Sci. USA 78:4170-4174.
27. 2 protein is an integral membrane protein expressed on the infected-cell surface. Cell 40:627-633.
28. Liu, S., S. Taffet, L. Stoner, M. Delmar, M. L. Vallano, and J. Jalife. 1993. A structural basis for the unequal sensitivity of the major cardiac and liver gap junctions to intracellular acidification: the carboxyl tail length. Biophys. J. 64:1422-1433.
29. 2 protein of influenza A H1N1 viruses. Virology 186:352-355.
30. 2 ectodomain is important for its incorporation into influenza A virions. J. Virol. 72:2449-2455.
31. 2 proton channel of influenza A virus suggests a mechanism for its ion selectivity. Proc. Natl. Acad. Sci. USA 94:11301-11306.
32. 2 protein has ion channel activity. Cell 69:517-528.
33. 2 protein affects transport through the Golgi apparatus. J. Cell Biol. 133:733-747.
34. 2 ion channel is a tetramer. Proc. Natl. Acad. Sci. USA 94:5000-5004.
35. 2 channel: a molecular modeling and simulation study. Virology 233:162-173.
36. 2 protein expressed by baculovirus: evidence for proton transfer activity. J. Gen. Virol. 75:3477-3484.
37. 2 ion channel of influenza virus. Biophys. J. 70:1335-1346.
38. Shimbo, K., D. L. Brassard, R A. Lamb, and L. H. Pinto. 1995. Viral and cellular small integral membrane proteins can modify ion channels endogenous to Xenopus oocytes. Biophys. J. 69:1819-1829.
39. 2 protein. Virology 179:51-56.
40. 2 protein of the influenza A viruses: evidence that it forms a tetrameric channel. Virology 180:617-624.
41. 2 ion channel in lipid bilayers. J. Membr. Biol. 142:117-126.
42. 2 protein of influenza A virus is acylated. Virology 184:227-234.
43. 2 ion channel of influenza virus: a role for the transmembrane domain histidine residue. Biophys. J. 69:1363-1371.
44. 2 protein ion channel activity in mammalian cells. Virology 205:133-140.
45. 2 protein: characterization of the amantadine block. J. Virol. 67:5585-5594.
46. 1 protein. Proc. Natl. Acad. Sci. USA 86:1061-1065.
47. 2 in virions. J. Virol. 62:2762-2772.
48. 2 integral membrane protein and expression at the infected-cell surface from cloned cDNA. J. Virol. 56:502-511.
49. 2 channel of influenza A virus: a molecular dynamics study. FEBS Lett. 434:265-271.