The effect of carbamazepine and sodium valproate on the blood and serum values of children from a third-world environment

Journal of Child Neurology

Volumn 14, Issue 11, 1999, Pages 751-753

  Hemingway, Cheryl ^a   Leary, Michael ^a,b   Riordan, Gillian ^a   Schlegal, Birgit ^a   Walker, Kathleen ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b RED CROSS WAR MEMORIAL CHILDREN S HOSPITAL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CARBAMAZEPINE; CHLORIDE ION; CREATININE; HEMOGLOBIN; POTASSIUM ION; SODIUM ION; UREA; VALPROIC ACID;

ABSENCE; ADOLESCENT; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ANTICONVULSANT THERAPY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CHILD; CHLORIDE BLOOD LEVEL; COMPLEX PARTIAL SEIZURE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; FEMALE; GRAND MAL EPILEPSY; HUMAN; MAJOR CLINICAL STUDY; MALE; MYOCLONUS EPILEPSY; POTASSIUM BLOOD LEVEL; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SODIUM BLOOD LEVEL; UREA BLOOD LEVEL;

EID: 0032732102     PISSN: 08830738     EISSN: None     Source Type: Journal    
DOI: 10.1177/088307389901401114     Document Type: Article

References (12)

1. Sobotka JL, Alexander B, Cook BL: A review of carbamazepine's hematologic reactions and monitoring recommendations. DICP Ann Pharmacother 1990;24:1214-1219.
2. Henry DA, Lawson DH, Reavey P, Renfrew S: Hyponatraemia during carbamazepine treatment. BMJ 1997;1:83-84.
3. Spickett GP, Gompels MM, Saunders PWG: Hypogammaglobulinaemia with absent B lymphocytes and agranulocytosis after carbamazepine treatment. J Neurol Neurosurg Psychiatry 1996;60:459-462.
4. Loiseau P: Sodium valproate, platelet dysfunction and bleeding. Epilepsia 1981;22:141-146.
5. Pedersen-Bjergaard U, Andersen M, Hansen PB: Thrombocytopenia induced by noncytotoxic drugs in Denmark 1968-1991. J Intern Med 1996;239:509-515.
6. Dreifuss FE, Santilli N, Langer DH, et al: Valproic acid hepatic fatalities: A retrospective review. Neurology 1987;37:379-385.
7. Joubert PH, Aucamp AK, Potgieter GM, Verster F: Epilepsy and IgA deficiency - the effect of sodium valproate. S Afr Med J 1977;52:642-644.
8. Henriksen O, Johannessen SI, Munthe-Kaas AW: How to use carbamazepine, in Morselli PL, Pippenger CE, Kiffin Penry J (eds): Anti-Epileptic Drug Therapy in Pediatrics. New York, Raven Press, 1983, pp 237-243.
9. Reynolds JEF (ed): Martindale. The Extra Pharmacopoeia. 31st ed. London, Royal Pharmaceutical Society, 1996, pp 237-243.
10. Tohen M, Castillo J, Baldessarini RJ, et al: Blood dyscrasias with carbamazepine ad valproate: A pharmacoepidemiological study of 2,228 patients at risk. Am J Psychiatry 1995;152:413-418.
11. Shulman G, Gilich GC: Serum immunoglobulins in black South African children. S Afr Med J 1976;50:1465-1467.
12. Camfield C, Camfield P, Smith E, Tibbles JAR: Asymptomatic children with epilepsy: Little benefit from screening for anti-convulsant induced liver, blood or renal damage. Neurology 1986;36:838-841.