Effectiveness and risks of total body irradiation for conditioning in the treatment of autoimmune disease with autologous bone marrow transplantation

Rheumatology

Volumn 38, Issue 8, 1999, Pages 757-761

  Van Bekkum, D W ^a  

^a CRUCELL HOLLAND BV   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; THYMOCYTE ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; AUTOIMMUNE DISEASE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; CARCINOGENESIS; CELL DESTRUCTION; CHILD; CONDITIONING; CONFERENCE PAPER; GROWTH INHIBITION; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; MEMORY CELL; MONKEY; NETHERLANDS; NONHUMAN; PRIORITY JOURNAL; RAT; RELAPSE; T LYMPHOCYTE; WHOLE BODY RADIATION;

ANIMALS; ARTHRITIS, JUVENILE RHEUMATOID; AUTOIMMUNE DISEASES; BONE MARROW TRANSPLANTATION; CHILD; COMBINED MODALITY THERAPY; CYCLOPHOSPHAMIDE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; MICE; RATS; T-LYMPHOCYTES; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME; WHOLE-BODY IRRADIATION;

EID: 0032731277     PISSN: 14620324     EISSN: None     Source Type: Journal    
DOI: 10.1093/rheumatology/38.8.757     Document Type: Conference Paper

References (26)

1. Knaan-Shanzer S, Houben P, Kinwel-Bohre EPM, van Bekkum DW. Remission induction of adjuvant arthritis in rats by total body irradiation and autologous bone marrow transplantation. Bone Marrrow Transplant 1991;8:333-8.
2. Van Gelder M, van Bekkum DW. Effective treatment of relapsing experimental autoimmune encephalomyelitis with pseudoautologous bone marrow transplantation. Bone Marrow Transplant 1996;18:1029-34.
3. Van Bekkum DW, Bohre EPM, Houben PFJ, Knaan-Shanzer S. Regression of adjuvant-induced arthritis in rats following bone marrow transplantation. Proc Natl Acad Sci USA 1989;86:10090-4.
4. Van Gelder M, van Bekkum DW. Treatment of relapsing experimental autoimmune encephalomyelitis in rats with allogeneic bone marrow transplantation from a resistant strain. Bone Marrow Transplant 1995;16:343-51.
5. Van Gelder M, Mulder AH, van Bekkum DW. Treatment of relapsing experimental autoimmune encephalomyelitis with largely MHC-matched allogeneic bone marrow transplantation. Transplantation 1996;62:810-8.
6. Van Bekkum DW. Review: BMT in experimental autoimmune diseases. Bone Marrow Transplant 1993;11: 183-7.
7. Marmont AM, van Bekkum DW. Stem cell transplantation for severe autoimmune diseases: new proposals but still unanswered questions. Bone Marrow Transplant 1995;16:497-8.
8. Van Gelder M, Kinwel-Bohré EPM, van Bekkum DW. Treatment of experimental allergic encephalomyelitis in rats with total body irradiation and syngeneic BMT. Bone Marrow Transplant 1993;11:233-41.
9. Van Gelder M. Bone marrow transplantation for treatment of experimental autoimmune encephalomyelitis in rats. Prospects for therapy of severe multiple sclerosis. Thesis, Leiden University, 1995.
10. Ikehara S, Yasumizu R, Inaba M et al. Long-term observations of autoimmune-prone mice treated for autoimmune disease by allogeneic bone marrow tranplantation. Immunology 1989;86:3306-10.
11. Loor F, Jachez B, Montecino-Rodriguez E et al. Radiation therapy of spontaneous autoimmunity: a review of mouse models. Int J Radiat Biol 1988;53:119-36.
12. Van Gelder M, Kinwel-Bohré EPM, Mulder AH, Van Bekkum DW. Both bone marrow and non-bone marrow-associated factors determine susceptibility to experimental autoimmune encephalomyelitis of BUF and WAG rats. Cell Immunol 1996;168:39-48.
13. Crook PR, Lucraft HH, Evans RG, Griffiths ID. Lack of effect of total body irradiation in rheumatoid arthritis. Br J Rheumatol 1986;25:384-7.
14. Euler HH, Schroeder JO, Harten P, Zeuner RA, Gutschmidt HJ. Treatment-free remission in severe systemic lupus erythematosus following synchronization of plasmapheresis with subsequent pulse cyclophosphamide. Arthritis Rheum 1994;37:1784-94.
15. Brodsky RA, Sensenbrenner LL, Jones RJ. Complete remission in severe aplastic anemia after high-dose cyclophosphamide without bone marrow transplantation. Blood 1996;87:491-4.
16. Pestronk A, Drachman DB, Teoh R, Adams RN. Combined short-term immunotherapy for experimental autoimmune myasthenia gravis. Ann Neurol 1983;14: 235-41.
17. Orme IM. Active and memory immunity to Lysteria monocytogenes infection in mice is mediated by phenotypically distinct T cell populations. Immunology 1989; 68:93-5.
18. Rouse BT, Hartley D, Doherty PC. Consequences of exposure to ionizing radiation for effector T cell function in vivo. Vir Immunol 1989;2:69-78.
19. Uzawa A, Suzuki G, Nakata Y et al. Radiosensitivity of CD45RO+ memory and CD45RO- naive T cells in culture. Radiat Res 1994;137:25-33.
20. Solleveld P, van Bekkum DW. The effect of whole body irradiation on skeletal growth in Rhesus monkeys. Radiology 1979;130:789-91.
21. Solleveld P, Peperkamp E, van Bekkum DW. Incidence of cataracts in Rhesus monkeys treated with whole body irradiation. Radiology 1979;133:227-9.
22. Recommendations of the International Commission on Radiation Protection, ICRP-26. Annals of the ICRP. Vol 1, No. 3. Oxford: Pergamon Press, 1977.
23. Dantal J, Hourmant M, Cantarovich D et al. Effect of long-term immunosuppression in kidney-graft recipients on cancer incidence: randomized comparison of two cyclosporin regimens. Lancet 1998;351:623-8.
24. Zurcher C, Varekamp AE, Solleveld HA et al. Late effects of cyclophosphamide and total body irradiation as a conditioning regimen for bone marrow transplantation in rats (a preliminary report). Int J Radiat Biol 1987;51: 1059-68.
25. Pincus T. The case for early intervention in rheumatoid arthritis. J Autoimmun 1992;5:209-26.
26. Radis CD, Kahl L, Baker GL et al. Effects of cyclophosphamide on the development of malignancy and on long term survival of patients with rheumatoid arthritis. A 20 year follow-up study. Arthritis Rheum 1995;38:1120-7.