Increased susceptibility to Toxoplasma gondii infection in SAG-1 transgenic mice

International Journal for Parasitology

Volumn 29, Issue 9, 1999, Pages 1433-1436

  Seng, Seyha ^a   Nagasawa, Hideyuki ^a   Maki, Yoshiyuki ^a   Yokoyama, Minesuke ^b   Inoue, Noboru ^a   Xuan, Xuenan ^a   Igarashi, Ikuo ^a   Saito, Atsushi ^a   Fujisaki, Kozo ^a   Mikami, Takeshi ^a   Suzuki, Naoyoshi ^a   Toyoda, Yutaka ^a  

^a OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

^b Mitsubishi Kasei Inst Life S   (Japan)

Author keywords

SAG 1; Susceptibility; Toxoplasma gondii; Transgenic mice

Indexed keywords

PARASITE ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; HOST PARASITE INTERACTION; HOST SUSCEPTIBILITY; MOUSE; NONHUMAN; PARASITE VIRULENCE; TOXOPLASMA GONDII; TOXOPLASMOSIS; TRANSGENIC MOUSE;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; DISEASE SUSCEPTIBILITY; MICE; MICE, TRANSGENIC; PROTOZOAN PROTEINS; TOXOPLASMA; TOXOPLASMOSIS, ANIMAL;

ANIMALIA; MUS MUSCULUS; PROTOZOA; TOXOPLASMA GONDII;

EID: 0032730258     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(99)00089-2     Document Type: Article

References (12)

1. Luft B.J., Remington J.S. Toxoplasmic encephalitis in AIDS. Clin Infect Dis. 15:1992;211-222.
2. Gazzinelli R.T., Wysocka M., Hayashi S.et al. Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii. J Immunol. 153:1994;2533-2543.
3. Hunter C.A., Abrams J.S., Beaman M.H., Remington J.S. Cytokine mRNA in the central nervous system of SCID mice infected with Toxoplasma gondii: importance of T-cell-independent regulation of resistance to T. gondii. Infect Immun. 61:1993;4038-4044.
4. Zaman V., Colley F.C. Ultrastructural study of penetration of macrophages by Toxoplasma gondii. Trans Royal Soc Trop Med Hyg. 66:1972;781-784.
5. Nichol B.A., O'Connor G.R. Penetration of mouse peritoneal macrophages by the protozoan Toxoplasma gondii. New evidence for active invasion and phagocytosis. Lab Invest. 44:1981;324-335.
6. Couvreur G., Sadak A., Fortier B., Dumbremetz J.F. Surface antigens of Toxoplasma gondii. Parasitol. 97:1988;1-10.
7. Boothroyd S.C., Hehi A., Kroll L.J., Mange I.D. The surface of Toxoplasma: more and less. Int J Parasitol. 28:1998;3-9.
8. Kasper L.H., Crabb J.H., Pfefferkorn E.R. Purification of a major membrane protein of Toxoplasma gondii by immunoadsorption with a monoclonal antibody. J Immunol. 130:1983;2407.
9. Johnson A.M., McDonald P.J., Neoh S.H. Monoclonal antibodies to Toxoplasma cell membrane surface antigens protect mice from toxoplasmosis. J Protozool. 30:1983;351-356.
10. Seng S., Maki Y., Yokoyama M.et al. Production of transgenic mice carrying p30 gene encoding major surface antigen of Toxoplasma gondii. J Protozool Res. 6:1996;121-128.
11. Gordon J.W., Ruddle F.H. Integration and stable germ line transmission of genes injected into mouse pronuclei. Science. 214:1981;1244-1246.
12. Pinkert CA. Transgenic animal technology. A Laboratory Handbook. Academic Press Inc, 1994.