Neutrophils from patients with advanced human immunodeficiency virus infection have impaired complement receptor function and preserved Fcγ receptor function

Journal of Infectious Diseases

Volumn 180, Issue 5, 1999, Pages 1542-1549

  Monari, Claudia ^a   Casadevall, Arturo ^b   Pietrella, Donatella ^a   Bistoni, Francesco ^a   Vecchiarelli, Anna ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C5A; FC RECEPTOR; GLUCURONOXYLOMANNAN; INTERLEUKIN 8; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ADULT; ARTICLE; CLINICAL ARTICLE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; CYTOKINE PRODUCTION; HIGH RISK POPULATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING;

ADULT; ANTIBODIES, MONOCLONAL; CANDIDA ALBICANS; COMPLEMENT C3A; COMPLEMENT C5A; CRYPTOCOCCUS NEOFORMANS; FLOW CYTOMETRY; HIV INFECTIONS; HUMANS; INTERLEUKIN-8; NEUTROPHILS; RECEPTORS, COMPLEMENT; RECEPTORS, IGG;

EID: 0032729808     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/315099     Document Type: Article

References (49)

1. 1. Murphy JW. Protective cell-mediated immunity against Cryptococcus neoformans. Res Immunol 1998;149:373-86.
2. 2. Huffnagle GB, Lipscomb MF. Cells and cytokines in pulmonary cryptococcosis. Res Immunol 1998;149:387-96.
3. 3. Graybill JR, Mitchell L. Cyclophosphamide effects on murine cryptococcosis. Infect Immun 1978;21:674-7.
4. 4. Graybill JR. Bocanegra R, Lambros C, Luther MF. Granulocyte colony stimulating factor therapy of experimental cryptococcal meningitis. J Med Vet Mycol 1997;35:243-7.
5. 5. Miller GPG, Kohl S. Antibody-dependent leucocyte killing of Cryptococcus neoformans. J Immunol 1983;131:1455-9.
6. 6. Miller MF, Mitchell TG. Killing of Cryptococcus neoformans strains by human neutrophils and monocytes. Infect Immun 1991;59:24-8.
7. 7. Davies SP, Clifford DP, Hoidal JR, Repine JE. Opsonic requirements for the uptake of Cryptocuccus neoformans by human polymorphonuclear leukocytes and monocytes. J Infect Dis 1982;145:870-4.
8. 8. Vecchiarelli A, Retini C, Casadevall A, Monari C, Pietrella D, Kozel TR. Involvement of C3a and C5a in interleukin-8 secretion by human polymorphonuclear cells in response to capsular material of Cryptococcus neoformans. Infect Immun 1998;66:4324-30.
9. 9. Vecchiarelli A, Casadevall A. Antibody-mediated effects against Cryptococcus neoformans: evidence for interdependency and collaboration between humoral and cellular immunity. Res Immunol 1998;149:321-33.
10. 10. Roilides E, Mertins S, Eddy S, Walsh TJ, Pizzo PA, Rubin M. Impairment of neutrophil chemotactic and bactericidal function in HIV-infected children and partial reversal lifter in vitro exposure to granulocyte-macrophage colony-stimulating factor. J Pediatr 1990;117:531-40.
11. 11. Cassone A, Palma C, Djeu JY, Aiuti F, Quinti I. Anticandidal activity and interleukin-1 and interleukin-6 production by polymorphonuclear leukocytes are preserved in subjects with AIDS. J Clin Microbiol 1993;31: 1354-7.
12. 12. Tascini C, Baldelli F, Monari C, et al. Inhibition of fungicidal activity of polymorphonuclear leukocytes from HIV-infected patients by interleukin (IL)-4 and IL-10. AIDS 1996;10:477-83.
13. 13. Cassatella MA. The production of cytokines by polymorphonuclear neutrophils. Immunol Today 1995;16:21-6.
14. 14. Strieter RM, Kasahara K, Allen RM, et al. Cytokine-induced neutrophil-derived interleukin-8. Am J Pathol 1992;141:397-407.
15. 15. Dubravec DB, Spriggs DR, Mannick JA, Rodrick ML. Circulating human peripheral blood granulocytes synthesize and secrete tumor necrosis factor-α. Proc Natl Acad Sci USA 1990;87:6758-61.
16. 16. Lindemann A, Riedel D, Oster W, Ziegler-Heitbrock HW, Mertelsmann R, Hermann F. Granulocyte-macrophage colony-stimulating factor induces cytokine secretion by human polymorphonuclear leukocytes. J Clin Invest 1989;83:1308-12.
17. 17. Westwick J, Li SW, Camp RD. Novel neutrophil-stimulating peptides. Immunol Today 1989;10:146-7.
18. 18. Wertheim WA, Kundel SL, Standiford TJ, et al. Regulation of neutrophil-derived IL-8: the role of prostaglandin E2, dexamethasone, and IL-4. J Immunol 1993;151:2166-75.
19. 19. Matsushima K, Oppenheim JJ. Interleukin-8 and MCAF: novel inflammatory cytokines inducible by IL-1 and TNF. Cytokine 1989;1:2-13.
20. 20. Liles WC, Van Hoorhis WC. Review: nomenclature and biologic significance of cytokines involved in inflammation and the last immune response. J Infect Dis 1995;172:1573-80.
21. 21. Lovchik JA, Lipscomb MF. Role for C5 and neutrophils in the pulmonary intra vascular clearance of circulating Cryptococcus neoformans. Am J Respir Cell Mol Biol 1993;9:617-27.
22. 22. Roilides E, Holmes A, Blake C, Pizzo PA, Walsh TJ. Impairment of neutrophil antifungal activity against hyphae of Aspergillus fumigatus in children infected with human immunodeficiency virus. J Infect Dis 1993;167; 905-11.
23. 23. Roilides E, Walsh T, Pizzo P, Rubin M. Granulocyte colony stimulation factor enhances the phagocytic and bactericidal activity of normal and defective human neutrophils. J Infect Dis 1991;163:579-83.
24. 24. Murphy PM, Lane CH, Fauci AS, Gallin JL. Impairment of neutrophil bactericidal capacity in patients with AIDS. J Infect Dis 1988;158:627-30.
25. 25. Vecchiarelli A, Monari C, Baldelli F, et al. Beneficial effect of recombinant human granulocyte colony-stimulating factor on fungicidal activity of polymorphonuclear leukocytes from patients with AIDS. J Infect Dis 1995;171:1448-54.
26. 26. Pitrak D, Bak P, De Marais P, Novak R, Andersen B. Depressed neutrophil superoxide production in human immunodeficiency virus infection. J Infect Dis 1993;167:1406-10.
27. 27. Chen T, Roberts RL, Wu KG, Ank BJ, Stiehm ER. Decreased superoxide anion and hydrogen peroxide production by neutrophils and monocytes in HIV-infected children and adults. Pediatr Res 1993;34:544-50.
28. 28. Torosantucci A, Chiani P, Quinti I, Ausiello CM, Mezzaroma I, Cassone A. Responsiveness of human polymorphonuclear cells (PMNL) to stimulation by a mannoprotein fraction (MP-F2) of Candida albicans: enhanced production of IL-6 and tumor necrosis factor-α (TNF-α) by MP-F2-stimulated PMNL from HIV-infected subjects. Clin Exp Immunol 1997;107:451-7.
29. 29. Cassone A, Chiani P. Quinti I, Torosantucci A. Possible participation of polymorphonuclear cells stimulated by microbial immunomodulators in the dysregulated cytokine patterns of AIDS patients. J Leukoc Biol 1997;62:60-6.
30. 30. Casadevall A, Cleare W, Feldmesser M, et al. Characterization of a murine monoclonal antibody to Cryptococcus neoformans polysaccharide that is a candidate for human therapeutic studies, Antimicrob Agents Chemother 1998;42:1437-46.
31. 31. Technical bulletin. Goat anti-C5. San Diego; Quidel, 1994.
32. 32. Vecchiarelli A, Doltorini M, Beccari T, Cociani C, Todisco T, Bistoni F. Inhibition of candidacidal activity of polymorphonuclear cells by alveolar macropbage-derived factor from lung cancer patients. Am Rev Respir Dis 1993;147:414-9.
33. 33. Vecchiarelli A, Dottorini M, Pietrella D, et al. Role of alveolar macrophages as antigen presenting cells in Cryptococcus neoformans infection. Am J Respir Cell Mol Biol 1994;11:130-7.
34. 34. Monari C, Casadevall A, Retini C, Baldelli F, Bistoni F, Vecchiarelli A, Antibody to capsular polysaccharide enhances the function of neutrophils from patients with AIDS against Cryptococcus neoformans. AIDS 1999; 13:653-60.
35. 35. Van Epps DE, Chenoweth DE. Analysis of the binding of fluorescent C5a and C3a to human peripheral blood leukocytes. J Immunol 1984;132: 2862-7.
36. 36. Baccarini M, Blasi E, Puccetti P, Bistoni K Phagocytic killing of Candida albicans by different murine effector cells. Sabouraudia 1983;21:271-86.
37. 37. Meddows-Taylor S, Martin DJ, Tiemessen CT. Dysregulated production of interleukin-8 in individuals infected with human immunodeficiency virus type 1 and Mycobacterium tuberculosis. Infect Immun 1999;67:1251-60.
38. 38. Gerard NP, Gerard C. The chemotactic receptor for human C5a anaphylatoxin. Nature 1991;349:614-7.
39. 39. Gerardy-Schahn R, Ambrosius D, Saunders D, et al. Characterization of C3a receptor-proteins on guinea pig platelets and human polymorpho-nuclear leukocytes. Eur J Immunol 1989;19:1095-102.
40. 40. Daffern PJ, Pfeifer PH, Ember JA, Hugli TE. C3a is a chemotaxin for human eosinophils but not for neutrophils. 1. C3a stimulation of neutrophils is secondary to eosinophil activation. J Exp Med 1995;181:2119-27.
41. 41. Hetland G, Pfeifer PH, Hugli TE. Processing of C5a by human polymorphonuclear leukocytes. J Leukoc Biol 1998;63:456-62.
42. 42. Bock D, Martin U, Gartner S, et al. The C terminus of the human C5a receptor (CD88) is required for normal ligand-dependent receptor internalization. Eur J Immunol 1997;27:1522-9.
43. 43. Ehrengruber MU, Geiser T, Deranleau DA. Activation of human neutrophils by C3a and C5a. Comparison of the effects on shape changes, chemotaxis, secretion, and respiratory burst. FEBS Lett 1994;346:181-4.
44. 44. Webster RO, Zanolari B, Henson PM. Neutrophil chemotaxis in response to surface-bound C5a. Exp Cell Res 1980;129:55-62.
45. 45. McPhail LC, Snyderrnan R. Activation of the respiratory burst enzyme in human polymorphonucleur leukocytes by chemoattractants and other soluble stimuli. Evidence that the same oxidase is activated by different transductional mechanisins. J Clin Invest 1983;72:192-200.
46. 46. Becker EL, Showell HJ, Henson PM, Hsu LS. The ability of chemotactic factors to induce lysosomal enzyme release. I. The characteristics of the release, the importance of surfaces and the relation of enzyme release to chemotactic responsiveness. J Immunol 1974;112:2047-54.
47. 47. Damerau DE, Grunefeld E, Vogt W. Aggregation of leukocytes induced by the complement-derived peptides C3a and C5a and by three, synthetic formyl-methionyl peptides. Int Arch Allergy Appl Immunol 1980;63: 159-69.
48. 48. Czermak BJ, Lentsch AB, Bless NM, Schmal H, Friedl HP, Ward PA. Role of complement in in vitro and in vivo lung inflammatory reactions. J Leukoc Biol 1998;64:40-8.
49. 49. Burg M, Martin U, Rheinheimer C, et al. IFN-γ up-regulates the human C5a receptor (CD88) in myeloblastic U937 cells and related cell lines. J Immunol 1995;155:4419-26.