Multilocus sequence typing and antigen gene sequencing in the investigation of a meningococcal disease outbreak

Journal of Clinical Microbiology

Volumn 37, Issue 12, 1999, Pages 3883-3887

  Feavers, Ian M ^a   Gray, Stephen J ^c   Urwin, Rachel ^b   Russell, Joanne E ^a,b   Bygraves, Jane A ^a   Kaczmarski, Edward B ^c   Maiden, Martin C J ^b  

^a NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c WITHINGTON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN;

ALLELE; ARTICLE; BACTERIUM ISOLATE; CONTROLLED STUDY; EPIDEMIC; GENE SEQUENCE; MENINGOCOCCOSIS; NEISSERIA MENINGITIDIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; STRAIN DIFFERENCE;

ANIMALIA; BACTERIA (MICROORGANISMS); NEGIBACTERIA; NEISSERIA MENINGITIDIS;

EID: 0032729330     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/jcm.37.12.3883-3887.1999     Document Type: Article

References (28)

1. Arhin, F. F., F. Moreau, J. W. Coulton, and E. L. Mills. 1998. Sequencing of porA from clinical isolates of Neisseria meningitidis defines a subtyping scheme and its genetic regulation. Can. J. Microbiol. 44:56-63.
2. Borrow, R., H. Claus, M. Guiver, L. Smart, D. M. Jones, E. B. Kaczmarski, M. Frosch, and A. J. Fox. 1997. Non-culture diagnosis and serogroup determination of meningococcal B and C infection by a sialyltransferase (siaD) PCR ELISA. Epidemiol. Infect. 118:111-117.
3. Bygraves, J. A., and M. C. J. Maiden. 1992. Analysis of the clonal relationships between strains of Neisseria meningitidis by pulsed field gel electrophoresis. J. Gen. Microbiol. 138:523-531.
4. Cartwright, K. A. V. (ed.). 1995. Meningococcal disease. John Wiley & Sons, Chichester, United Kingdom.
5. Caugant, D. A., L. F. Mocca, C. E. Frasch, L. O. Froholm, W. D. Zollinger, and R. K. Selander. 1987. Genetic structure of Neisseria meningitidis populations in relation to serogroup, serotype, and outer membrane protein pattern. J. Bacteriol. 169:2781-2792.
6. Chan, M.-S. 1998, posting date. MLST Website. [Online.] http://mlst.zoo.ox .ac.uk [6 October 1999, last date accessed.]
7. Dempsey, J. A., A. B. Wallace, and J. G. Cannon. 1995. The physical map of the chromosome of a serogroup A strain of Neisseria meningitidis shows complex rearrangements relative to the chromosome of the two mapped strains of the closely related species N. gonorrhoeae. J. Bacteriol. 177:6390-6400.
8. Derrick, J. P., R. Urwin, J. Suker, I. M. Feavers, and M. C. J. Maiden. 1999. Structural and evolutionary inference from molecular variation in Neisseria porins. Infect. Immun. 67:2406-2413.
9. Feavers, I. M., J. Suker, A. J. McKenna, A. B. Heath, and M. C. J. Maiden. 1992. Molecular analysis of the serotyping antigens of Neisseria meningitidis. Infect. Immun. 60:3620-3629.
10. Frasch, C. E., W. D. Zollinger, and J. T. Poolman. 1985. Serotype antigens of Neisseria meningitidis and a proposed scheme for designation of serotypes. Rev. Infect. Dis. 7:504-510.
11. Holmes, E. C., R. Urwin, and M. C. J. Maiden. 1999. The influence of recombination on the population structure and evolution of the human pathogen Neisseria meningitidis. Mol. Biol. Evol. 16:741-749.
12. Jelfs, J., R. Munro, F. Ashton, W. Rawlinson, and D. A. Caugant. 1998. Global study of variation in a new variant of the ET-37 complex of Neisseria meningitidis, p. 5. In Proceedings of the Eleventh Pathogenic Neisseria Conference. Editions E.D.K., Paris, France.
13. Maiden, M. C. J. 1998. The impact of molecular techniques on the study of meningococcal disease, p. 265-291. In N. Woodford and A. P. Johnson (ed.), Molecular bacteriology: protocols and clinical applications. Humana Press, Totowa, N.J.
14. Maiden, M. C. J., J. A. Bygraves, E. Feil, G. Morelli, J. E. Russell, R. Urwin, Q. Zhang, J. Zhou, K. Zurth, D. A. Caugant, I. M. Feavers, M. Achtman, and B. G. Spratt. 1998. Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms. Proc. Natl. Acad. Sci. USA 95:3140-3145.
15. Maiden, M. C. J., and I. M. Feavers. 1994. Meningococcal typing. J. Med. Microbiol. 40:157-158.
16. Maiden, M. C. J., and I. M. Feavers. 1995. Population genetics and global epidemiology of the human pathogen Neisseria meningitidis, p. 269-293. In S. Baumberg, J. P. W. Young, E. M. H. Wellington, and J. R. Saunders (ed.), Population genetics of bacteria. Cambridge University Press, Cambridge, United Kingdom.
17. Maiden, M. C. J., J. Suker, A. J. McKenna, J. A. Bygraves, and I. M. Feavers. 1991. Comparison of the class 1 outer membrane proteins of eight serological reference strains of Neisseria meningitidis. Mol. Microbiol. 5:727-736.
18. Olyhoek, T., B. A. Crowe, and M. Achtman. 1987. Clonal population structure of Neisseria meningitidis serogroup A isolated from epidemics and pandemics between 1915 and 1983. Rev. Infect. Dis. 9:665-682.
19. Rokbi, B. M. Mignon, D. A. Caugant, and M. J. Quentin-Millet. 1997. Heterogeneity of tbpB, the transferrin-binding protein B gene, among serogroup B Neisseria meningitidis strains of the ET-5 complex. Clin. Diagn. Lab. Immunol. 4:522-529.
20. Selander, R. K., D. A. Caugant, H. Ochman, J. M. Musser, M. N. Gilmour, and T. S. Whittam. 1986. Methods of multilocus enzyme electrophoresis for bacterial population genetics and systematics. Appl. Environ. Microbiol. 51:837-884.
21. Staden, R. 1996. The Staden sequence analysis package. Mol. Biotechnol. 5:233-241.
22. Suker, J., I. M. Feavers, M. Achtman, G. Morelli, J.-F. Wang, and M. C. J. Maiden. 1994. The porA gene in serogroup A meningococci: evolutionary stability and mechanism of genetic variation. Mol. Microbiol. 12:253-265.
23. Suker, J., I. M. Feavers, and M. C. J. Maiden. 1996. Monoclonal antibody recognition of members of the P1.10 variable region family: implications for serological typing and vaccine design. Microbiology 142:63-69.
24. Urwin, R. 1998. Ph.D. thesis. University of Staffordshire, Stoke-on-Trent, United Kingdom.
25. Urwin, R., I. M. Feavers, D. M. Jones, M. C. J. Maiden, and A. J. Fox. 1998. Molecular variation of meningococcal serotype 4 antigen genes. Epidemiol. Infect. 121:95-101.
26. Vogel, U., G. Morelli, K. Zurth, H. Claus, E. Kriener, M. Achtman, and M. Frosch. 1998. Necessity of molecular techniques to distinguish between Neisseria meningitidis strains isolated from patients with meningococcal disease and from their healthy contacts. J. Clin. Microbiol. 36:2465-2470.
27. Wang, J.-F., D. A. Caugant, G. Morelli, B. Koumaré, and M. Achtman. 1993. Antigenic and epidemiological properties of the ET-37 complex of Neisseria meningitidis. J. Infect. Dis. 167:1320-1329.
28. Williams, J. N., G. R. Jones, M. Christodoulides, K. Jolley, and J. E. Heckels. 1998. Investigation into an outbreak of meningococcal infection at Southampton University, p. 254. In Proceedings of the Eleventh International Pathogenic Neisseria Conference, Editions E.D.K., Paris, France.