Modulating experimental diabetes by treatment with cytosolic extract from the regenerating pancreas

Diabetes Research and Clinical Practice

Volumn 46, Issue 3, 1999, Pages 203-211

  Hardikar, Anandwardhan A ^a   Bhonde, Ramesh R ^a  

^a National Centre of Cell Sciences   (India)

Author keywords

Diabetes reversal; Islet neogenesis; Pancreatic regeneration

Indexed keywords

ANTIDIABETIC AGENT; GROWTH FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; HYPERGLYCEMIA; MOUSE; NONHUMAN; PANCREAS; TISSUE REGENERATION;

ANIMALS; BLOOD GLUCOSE; CYTOSOL; DIABETES MELLITUS, EXPERIMENTAL; FASTING; GLUCOSE TOLERANCE TEST; IMAGE PROCESSING, COMPUTER-ASSISTED; INSULIN; MICE; MICE, INBRED BALB C; PANCREAS; REGENERATION; TISSUE EXTRACTS;

EID: 0032729313     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8227(99)00098-4     Document Type: Article

References (22)

1. Bonner-Weir S., Baxter L.A., Schuppin G.T., Smith F.E. A second pathway for regeneration of adult exocrine and endocrine pancreas: a possible recapitulation of embryonic development. Diabetes. 42:1993;1715-1720.
2. Slack J.M. Developmental biology of the pancreas. Development. 121:1995;1569-1580.
3. Hardikar A.A., Karandikar M.S., Bhonde R.R. Effect of partial pancreatectomy on diabetic status in BALB/c mice. J. Endocrinol. 162:1999;189-195.
4. Hellerstrom C., Swenne I., Andersson A. Islet cell replication and diabetes. Steiner D., Freinkel N. Handbook of Physiology: The Endocrine Pancreas. Section 8. 1:1972;25-66 Williams and Wilkins, Baltimore, MD.
5. Elsasser H.P., Lutcke H., Kern H.F. Acinar and duct cell replication and regeneration. Go V.L.W., Dimagno E.P., Gardner J.D., Lebenthal E., Ceber H.A., Scheele G.A. The Exocrine Pancreas: Biology, Pathobiology and Diseases. 1986;45-53 Raven, New York.
6. Swenne I. Effect of ageing on the regenerative capacity of pancreatic β cell of the rat. Diabetes. 32:1983;14-19.
7. Tanigawa K., Nakamura S., Kawaguchi M., Xu G., Kin S., Tamura K. Effect of aging on B-cell function and replication in rat pancreas after 90% pancreatectomy. Pancreas. 15:1997;53-59.
8. Jindal R.M., Sidner R.A., Cummings O., Miller G.A., Filo R.S. Proliferation of rat pancreatic ductal epithelial cells in vitro and in response to partial hepatectomy and pancreatectomy in vivo. Transpl. Proc. 27:1995;2991-2992.
9. Gotoh M., Maki T., Kiyoizumi T., Satomi S., Monaco A.P. An improved method for isolation of mouse pancreatic islets. Transplantation. 40:1985;437-438.
10. Teitelman G., Alpert S., Hanahan D. Proliferation, senescence and neoplastic progression of beta cells in hyperplasic pancreatic islets. Cell. 52:1988;97-105.
11. Brockenbrough J.S., Weir G.C., Bonner-Weir S. Discordance of exocrine and endocrine growth after 90% pancreatectomy in rats. Diabetes. 37:1988;232-236.
12. Parekh D., Townsend C.M., Rajaraman S., Ishizuka J., Thompson J.C. Pancreatic regeneration after partial pancreatectomy. Am. J. Surg. 161:1991;84-89.
13. Wang R.N., Kloppel G., Bouwens L. Duct-to islet-cell differentiation and islet growth in the pancreas of duct ligated adult rats. Diabetologia. 38:1995;1405-1411.
14. Topp J., Korsgren O., Welsh N., Jansson L. Evidence of a negative feedback system regulating the total beta-cell volume in non-diabetic rats that received pancreas transplant. Transplantation. 66:1998;1392-1394.
15. Ziegler B., Lucke S., Besch W., Hahn H.J. Early enhanced beta cell replication in normoglycemic Wistar rats in response to a subdiabetogenic dose of streptozotocin. Exp. Clin. Endocrinol. 93:1989;1-10.
16. Baeza N.J., Moriscot C.I., Renaud W.P., Okamoto H., Figarella C.G., Vialettes B.H. Pancreatic regeneration gene over-expression in the non-obese diabetic mouse during active diabetogenesis. Diabetes. 45:1996;67-70.
17. Ohno T., Ishii C., Kato N., Ito Y., Shimizu M., Tomono S., Murata K., Kawazu S. Increased expression of a regenerating (reg) gene protein in neonatal rat pancreas treated with streptozotocin. Endocr. J. 42:1995;649-653.
18. Lampeter E.F., Tubes M., Klemens C., Brocker U., Friemann J., Kolb-Bachofen V., Gries F.A., Kolb H. Insulitis and islet-cell antibody formation in rats with experimentally reduced beta-cell mass. Diabetologia. 38:1995;1397-1404.
19. Rosenberg L., Vinik A.I., Pittenger G.L., Rafaeloff R., Duguid W.P. Islet cell regeneration in the diabetic hamster pancreas with restoration of normoglycemia can be induced by a local growth factor(s). Diabetologia. 39:1996;256-262.
20. Rosenberg L. In vivo cell transformation: neogenesis of beta cells from pancreatic ductal cells. Cell Transpl. 4:1995;371-383.
21. Rosenberg L., Brown R.A., Duguid W.P. A new approach to the induction of duct epithelial hyperplasia and nesidioblastosis by cellophane wrapping of the hamster pancreas. J. Surg. Res. 35:1983;63-72.
22. Rosenberg L., Vinik A.I. In vitro stimulation of hamster pancreatic duct growth by an extract from the 'wrapped' pancreas. Pancreas. 8:1993;255-260.