Systematic search for disease loci for complex genetic traits: A study based on simulated population data

Genetic Epidemiology

Volumn 17, Issue SUPPL. 1, 1999, Pages

  Falk, Catherine T ^a  

^a NEW YORK BLOOD CENTER   (United States)

Author keywords

Heterogeneity; Linkage analysis; Multilocus models

Indexed keywords

CHROMOSOME 3; CHROMOSOME 5; CHROMOSOME ANALYSIS; CONFERENCE PAPER; DISEASE MARKER; DISEASE MODEL; GENETIC ANALYSIS; GENETIC HETEROGENEITY; GENETIC LINKAGE; HUMAN; POPULATION RESEARCH; SIMULATION;

EID: 0032728340     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/gepi.1370170789     Document Type: Conference Paper

References (6)

1. Falk C (1993): Effective strategies for linkage analysis of genetically heterogeneous traits. Am J Hum Genet 53:A65 (abstract).
2. Kruglyak L, Daly MJ, Reeve-Daly MP, Lander, ES (1996): Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet 58:1347-1363.
3. Lathrop GM, Ott J (1990): Analysis of complex diseases under oligogenic models and intrafamilial heterogeneity by the LINKAGE programs. Am J Hum Genet 47:A188 (abstract).
4. Lathrop GM, Lalouel JM, Julier C, Ott J (1985): Multilocus linkage analysis in humans: detection of linkage and estimation of recombination. Am J Hum Genet 37:482-498.
5. Ott J (1991): "Analysis of Human Genetic Linkage." Baltimore: Johns Hopkins University Press.
6. Schork NJ, Boehnke M, Terwilliger JD, Ott J (1993): Two-trait-locus linkage analysis: a powerful strategy for mapping complex genetic traits. Am J Hum Genet 53:1127-1136.