-
1
-
-
0010559843
-
-
NIH Publication No. 95-3924
-
NIDDK (National Institute of Diabetes and Digestive and Kidney Diseases). Acromegaly. NIH Publication No. 95-3924, 1995.
-
(1995)
Acromegaly
-
-
-
2
-
-
0025700486
-
Acromegaly
-
Melmed, S. Acromegaly. New Engl J Med 1990, 322: 966-77.
-
(1990)
New Engl J Med
, vol.322
, pp. 966-977
-
-
Melmed, S.1
-
3
-
-
0026758047
-
Radiation therapy of acromegaly
-
Eastman, R.C., Gorden, P., Glatstein, E., Roth, J. Radiation therapy of acromegaly. Endocrinol Metab Clin North Am 1992, 21: 693-711.
-
(1992)
Endocrinol Metab Clin North Am
, vol.21
, pp. 693-711
-
-
Eastman, R.C.1
Gorden, P.2
Glatstein, E.3
Roth, J.4
-
4
-
-
0028032209
-
Management of acromegaly: A review
-
Krishna, A.Y., Phillips, L.S. Management of acromegaly: A review. Am J Med Sci 1994, 308: 370-5.
-
(1994)
Am J Med Sci
, vol.308
, pp. 370-375
-
-
Krishna, A.Y.1
Phillips, L.S.2
-
5
-
-
0027793074
-
Results of treatment for acromegaly with long-acting bromocriptine
-
Bednarek-Tupikowska, G., Bohdanowicz-Pawlak, A., Bolanowski, M., Jedrzejak, J., Milewicz, A. Results of treatment for acromegaly with long-acting bromocriptine. Endokrynol Pol 1993, 44: 161-8.
-
(1993)
Endokrynol Pol
, vol.44
, pp. 161-168
-
-
Bednarek-Tupikowska, G.1
Bohdanowicz-Pawlak, A.2
Bolanowski, M.3
Jedrzejak, J.4
Milewicz, A.5
-
7
-
-
0031980378
-
Novel somatostatin analogs for the treatment of acromegaly and cancer exhibit improved in vivo stability and distribution
-
Gillespie, T.J., Erenberg, A., Kim, S., Dong, J., Taylor, J.E., Hau, V., Davis, T.P. Novel somatostatin analogs for the treatment of acromegaly and cancer exhibit improved in vivo stability and distribution. J Pharmacol Exp Ther 1998, 285: 95-104.
-
(1998)
J Pharmacol Exp Ther
, vol.285
, pp. 95-104
-
-
Gillespie, T.J.1
Erenberg, A.2
Kim, S.3
Dong, J.4
Taylor, J.E.5
Hau, V.6
Davis, T.P.7
-
8
-
-
0029111738
-
Safety and efficacy of long-term octreotide therapy of acromegaly: Results of a multicenter trial in 103 patients. A clinical research center study
-
Newman, C.B., Melmed, S., Snyder, P.J., Young, W.F., Boyajy, L.D., Levy, R., Stewart, W.N., Klibanski, A., Molitch, M.E., Gagel, R.F. Safety and efficacy of long-term octreotide therapy of acromegaly: Results of a multicenter trial in 103 patients. A clinical research center study. J Clin Endocrinol Metab 1995, 80: 2768-75.
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 2768-2775
-
-
Newman, C.B.1
Melmed, S.2
Snyder, P.J.3
Young, W.F.4
Boyajy, L.D.5
Levy, R.6
Stewart, W.N.7
Klibanski, A.8
Molitch, M.E.9
Gagel, R.F.10
-
9
-
-
0028134890
-
Consensus statement: Benefits versus risks of medical therapy for acromegaly
-
Acromegaly Therapy Consensus Development Panel. Consensus statement: Benefits versus risks of medical therapy for acromegaly. Am J Med 1994, 97: 468-73.
-
(1994)
Am J Med
, vol.97
, pp. 468-473
-
-
-
10
-
-
0013368585
-
The antagonist action of B2036 on growth hormone signalling is independent of receptor internalisation
-
Abst P168.
-
Maamra, M., Von Laue, S., Simon, S., Justice, S., Finidori, J., Dower, S.K., Ross, R.J.M. The antagonist action of B2036 on growth hormone signalling is independent of receptor internalisation. J Endocrinol 1999, 160(Suppl.): Abst P168.
-
(1999)
J Endocrinol
, vol.160
, Issue.SUPPL.
-
-
Maamra, M.1
Von Laue, S.2
Simon, S.3
Justice, S.4
Finidori, J.5
Dower, S.K.6
Ross, R.J.M.7
-
11
-
-
0344385283
-
GH, the GH antagonist (Trovert), and GH receptor (GHR) trafficking studied by dual fluorescent confocal microscopy
-
(June 12-15, San Diego) Abst P1-95
-
Maamra, M., Finidori, J., Von Laue, S., Simon, S., Justice, S., Webster, J., Dower, S.K., Ross, R.J.M. GH, the GH antagonist (Trovert), and GH receptor (GHR) trafficking studied by dual fluorescent confocal microscopy. 81st Annu Meet Endocr Soc (June 12-15, San Diego) 1999, Abst P1-95.
-
(1999)
81st Annu Meet Endocr Soc
-
-
Maamra, M.1
Finidori, J.2
Von Laue, S.3
Simon, S.4
Justice, S.5
Webster, J.6
Dower, S.K.7
Ross, R.J.M.8
-
12
-
-
0033047377
-
Inhibitory effect of a growth hormone receptor antagonist (G120K-PEG) on renal enlargement, glomerular hypertrophy, and urinary albumin excretion in experimental diabetes in mice
-
Flyvbjerg, A., Bennett, W.F., Rasch, R., Kopchick, J.J., Scarlett, J.A. Inhibitory effect of a growth hormone receptor antagonist (G120K-PEG) on renal enlargement, glomerular hypertrophy, and urinary albumin excretion in experimental diabetes in mice. Diabetes 1999, 48: 377-82.
-
(1999)
Diabetes
, vol.48
, pp. 377-382
-
-
Flyvbjerg, A.1
Bennett, W.F.2
Rasch, R.3
Kopchick, J.J.4
Scarlett, J.A.5
-
13
-
-
0345679834
-
Effect of a long-acting growth hormone receptor antagonist (G120K-PEG) on renal enlargement, glomerular hypertrophy and urinary albumin excretion in experimental diabetes in mice
-
Abst 10
-
Flyvbjerg, A., Bennett, W., Rasch, R., Kopchick, J.J., Scarlett, J.A. Effect of a long-acting growth hormone receptor antagonist (G120K-PEG) on renal enlargement, glomerular hypertrophy and urinary albumin excretion in experimental diabetes in mice. Eur J Endocrinol 1998, 138(Suppl. 1): Abst 10.
-
(1998)
Eur J Endocrinol
, vol.138
, Issue.SUPPL. 1
-
-
Flyvbjerg, A.1
Bennett, W.2
Rasch, R.3
Kopchick, J.J.4
Scarlett, J.A.5
-
14
-
-
0344385284
-
The growth hormone receptor antagonist B2036PEG (Trovert) inhibits the growth of breast cancer xenografts in nude mice
-
(June 12-15, San Diego) Abst PS-122
-
Roshan, S.Y., McCutcheon, I.E., Bennett, W.F., Hill, H.L., Scarlett, J.A., Flyvbjerg, A., Friend, K.E. The growth hormone receptor antagonist B2036PEG (Trovert) inhibits the growth of breast cancer xenografts in nude mice. 81st Annu Meet Endocr Soc (June 12-15, San Diego) 1999, Abst PS-122.
-
(1999)
81st Annu Meet Endocr Soc
-
-
Roshan, S.Y.1
McCutcheon, I.E.2
Bennett, W.F.3
Hill, H.L.4
Scarlett, J.A.5
Flyvbjerg, A.6
Friend, K.E.7
-
15
-
-
0344385279
-
The growth hormone receptor antagonist B2036PEG (Trovert) inhibits the growth of meningioma xenografts in nude mice
-
Abst 4047
-
McCutcheon, I.E., Bennett, W.F., Hill, H.L., Li, T., Radinsky, R., Scarlett, J.A., Zhang, B.M., Friend, K.E. The growth hormone receptor antagonist B2036PEG (Trovert) inhibits the growth of meningioma xenografts in nude mice. Proc Amer Assoc Cancer Res 1999, 40: Abst 4047.
-
(1999)
Proc Amer Assoc Cancer Res
, vol.40
-
-
McCutcheon, I.E.1
Bennett, W.F.2
Hill, H.L.3
Li, T.4
Radinsky, R.5
Scarlett, J.A.6
Zhang, B.M.7
Friend, K.E.8
-
16
-
-
0344385282
-
The human growth hormone antagonist B2036-PEG (Trovert™) has no agonistic or antagonistic effect on the human prolactin receptor
-
(June 12-15, San Diego) Abst P1-94
-
Coffin, V., Bernichtein, S., Carriere, O., Kopchick, J.J., Bennett, W.F., Kelly, P.A. The human growth hormone antagonist B2036-PEG (Trovert™) has no agonistic or antagonistic effect on the human prolactin receptor. 81st Annu Meet Endocr Soc (June 12-15, San Diego) 1999 Abst P1-94.
-
(1999)
81st Annu Meet Endocr Soc
-
-
Coffin, V.1
Bernichtein, S.2
Carriere, O.3
Kopchick, J.J.4
Bennett, W.F.5
Kelly, P.A.6
-
17
-
-
0013363184
-
Development of a sensitive radioimmunoassay for the quantification of B2036-PEG in human serum: Validation and its application in a phase I study
-
Abst 4160
-
Khan, M.N., Lu, Y.R., Pham, K., Zib, K. Development of a sensitive radioimmunoassay for the quantification of B2036-PEG in human serum: Validation and its application in a phase I study. Pharm Res 1997, 14(11, Suppl.): Abst 4160.
-
(1997)
Pharm Res
, vol.14
, Issue.11 SUPPL.
-
-
Khan, M.N.1
Lu, Y.R.2
Pham, K.3
Zib, K.4
-
18
-
-
0013362210
-
Single-dose safety and pharmacokinetics of B2036-PEG (Somavert) after subcutaneous administration in healthy volunteers
-
Abst 50
-
Rodvold, K.A., Bennett, W.F., Zib, K.A. Single-dose safety and pharmacokinetics of B2036-PEG (Somavert) after subcutaneous administration in healthy volunteers. J Clin Pharmacol 1997, 37: Abst 50.
-
(1997)
J Clin Pharmacol
, vol.37
-
-
Rodvold, K.A.1
Bennett, W.F.2
Zib, K.A.3
-
19
-
-
0013459524
-
Pharmacokinetics and pharmacodynamics of B2036-PEG, a novel growth hormone receptor antagonist, in acromegalic subjects
-
(June 12-15, San Diego) Abst P1-49
-
Rodvold, K.A., van der Lely, A.J. Pharmacokinetics and pharmacodynamics of B2036-PEG, a novel growth hormone receptor antagonist, in acromegalic subjects. 81st Annu Meet Endocr Soc (June 12-15, San Diego) 1999, Abst P1-49.
-
(1999)
81st Annu Meet Endocr Soc
-
-
Rodvold, K.A.1
Van Der Lely, A.J.2
-
20
-
-
0033305394
-
Growth hormone (GH) receptor blockade with a PEG-modified GH (B2036-PEG) lowers serum insulin-like growth factor-I but does not acutely stimulate serum GH
-
Thorner, M.O., Strasburger, C.J., Wu, Z., Straume, M., Bidlingmaier, M., Pezzoli, S.S., Zib, K., Scarlett, J.C., Bennett, W.F. Growth hormone (GH) receptor blockade with a PEG-modified GH (B2036-PEG) lowers serum insulin-like growth factor-I but does not acutely stimulate serum GH. J Clin Endocrinol Metab 1999, 84:2098-103.
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 2098-2103
-
-
Thorner, M.O.1
Strasburger, C.J.2
Wu, Z.3
Straume, M.4
Bidlingmaier, M.5
Pezzoli, S.S.6
Zib, K.7
Scarlett, J.C.8
Bennett, W.F.9
-
21
-
-
0344385280
-
Successful treatment of acromegaly with a growth hormone receptor antagonist (Trovert™)
-
Abst OC23
-
Trainer, P.J., Drake, W.M., Conrich, L., Monson, J.P., Besser, G.M. Successful treatment of acromegaly with a growth hormone receptor antagonist (Trovert™). J Endocrinol 1998, 159(Suppl.): Abst OC23.
-
(1998)
J Endocrinol
, vol.159
, Issue.SUPPL.
-
-
Trainer, P.J.1
Drake, W.M.2
Conrich, L.3
Monson, J.P.4
Besser, G.M.5
-
22
-
-
0343322699
-
Treatment of acromegaly with B2036-PEG, a growth hormone receptor antagonist
-
(June 12-15, San Diego) Abst OR14-6
-
Barkan, A., Dimaraki, E., Besser, G.M. et al. Treatment of acromegaly with B2036-PEG, a growth hormone receptor antagonist. 81st Annu Meet Endocr Soc (June 12-15, San Diego) 1999, Abst OR14-6.
-
(1999)
81st Annu Meet Endocr Soc
-
-
Barkan, A.1
Dimaraki, E.2
Besser, G.M.3
-
23
-
-
0345248112
-
Growth hormone receptor antagonist therapy for acromegaly
-
(June 12-15, San Diego) Abst S21-3
-
Trainer, P.J., Drake, W.M., Besser, M. Growth hormone receptor antagonist therapy for acromegaly. 81st Annu Meet Endocr Soc (June 12-15, San Diego) 1999, Abst S21-3.
-
(1999)
81st Annu Meet Endocr Soc
-
-
Trainer, P.J.1
Drake, W.M.2
Besser, M.3
-
24
-
-
0013364860
-
Modulation of cortisol metabolism by a growth hormone receptor antagonist (Trovert ™) in patients with acromegaly
-
Abst OC33
-
Trainer, P.J., Drake, W.M., Conrich, L., Taylor, N.F., Besser, G.M., Monson, J.P. Modulation of cortisol metabolism by a growth hormone receptor antagonist (Trovert ™) in patients with acromegaly. J Endocrinol 1999, 160(Suppl.): Abst OC33.
-
(1999)
J Endocrinol
, vol.160
, Issue.SUPPL.
-
-
Trainer, P.J.1
Drake, W.M.2
Conrich, L.3
Taylor, N.F.4
Besser, G.M.5
Monson, J.P.6
-
25
-
-
0344817021
-
Monitoring the treatment of acromegaly with B2036-PEG using acid labile subunit (ALS) levels
-
(June 12-15, San Diego) Abst P1-48
-
Morrison, K.M., Bidlingmaier, M., Stadler, S., Wu, Z., Zib, K., Bennett, W.F., Strasburger, C.J. Monitoring the treatment of acromegaly with B2036-PEG using acid labile subunit (ALS) levels. 81st Annu Meet Endocr Soc (June 12-15, San Diego) 1999, Abst P1-48.
-
(1999)
81st Annu Meet Endocr Soc
-
-
Morrison, K.M.1
Bidlingmaier, M.2
Stadler, S.3
Wu, Z.4
Zib, K.5
Bennett, W.F.6
Strasburger, C.J.7
-
26
-
-
0345679832
-
A phase III study of B2036, a growth hormone antagonist, in the treatment of acromegaly
-
(June 12-15, San Diego) Abst P1-46
-
Trainer, P.J., Besser, G.M., Klibanski, A., Freda, P.U., Melmed, S. A phase III study of B2036, a growth hormone antagonist, in the treatment of acromegaly. 81st Annu Meet Endocr Soc (June 12-15, San Diego) 1999, Abst P1-46.
-
(1999)
81st Annu Meet Endocr Soc
-
-
Trainer, P.J.1
Besser, G.M.2
Klibanski, A.3
Freda, P.U.4
Melmed, S.5
-
27
-
-
0345679833
-
Growth hormone receptor antagonist induces improvement in insulin resistance in acromegaly
-
(June 12-15, San Diego) Abst P1-47
-
Rose, D.R. Jr., Clemmons, D.R. Growth hormone receptor antagonist induces improvement in insulin resistance in acromegaly. 81st Annu Meet Endocr Soc (June 12-15, San Diego) 1999, Abst P1-47.
-
(1999)
81st Annu Meet Endocr Soc
-
-
Rose D.R., Jr.1
Clemmons, D.R.2
|