Synthesis, structural characterization and thromboxane A2 receptor antagonistic activity of 3-substituted 2-[(arylsulfonyl)imino]-2,3- dihydrothiazolyl derivatives

European Journal of Medicinal Chemistry

Volumn 34, Issue 4, 1999, Pages 311-328

  Lacan, Fabrice ^a   Varache Lembège, Martine ^a   Vercauteren, Joseph ^a   Léger, Jean Michel ^a   Masereel, Bernard ^b   Dogné, Jean Michel ^c   Nuhrich, Alain ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b UNIVERSITY OF NAMUR   (Belgium)

^c UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

2,3 Dihydrothiazole derivatives; Platelet anti aggregants; Receptor binding; Three dimensional structure analysis; Thromboxane A2 antagonists

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 2 [(ARYLSULFONYL)IMINO] 2,3 DIHYDROTHIAZOLYL DERIVATIVE; 2 [2,3 DIHYDRO 2 [(PHENYLSULFONYL)IMINO]THIAZOL 3 YL]PHENOXYACETIC ACID; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; ADENOSINE DIPHOSPHATE; ARYLSULFONIC ACID DERIVATIVE; COLLAGEN; PROSTAGLANDIN H2; THIAZOLE DERIVATIVE; THROMBOXANE A2 RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; THROMBOCYTE AGGREGATION; X RAY CRYSTALLOGRAPHY;

EID: 0032727674     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(99)80082-8     Document Type: Review

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