1,2-Dichloropropane

IARC Monographs on the Evaluation of Carcinogenic Risks to Humans

Volumn 71 III, Issue , 1999, Pages 1393-1400

[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

CHLORINE DERIVATIVE; PROPANE;

CARCINOGENICITY; CHEMICAL STRUCTURE; CONFERENCE PAPER; EVALUATION; EXPOSURE; HUMAN; LIVER TUMOR; NONHUMAN; PRIORITY JOURNAL; TOXICITY; TOXICOKINETICS;

ANIMALS; BACTERIA; CARCINOGENICITY TESTS; CARCINOGENS; HUMANS; MUTAGENICITY TESTS; MUTAGENS; NEOPLASMS, EXPERIMENTAL; PROPANE; SOLVENTS;

EID: 0032726804     PISSN: 02509555     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (25)

1. Bartels, M.J. & Timchalk, C. (1990) 1,2-Dichloropropane: investigation of the mechanism of mercapturic acid formation in the rat. Xenobiotica, 20, 1035-1042
2. Baruffini, A., Cirla, A.M., Pisati, G., Ratti, R. & Zedda, S. (1989) Allergic contact dermatitis from 1,2-dichloropropane. Contact Derm., 20, 379-380
3. Bruckner, J.V., Mackenzie, W.F., Ramanathan, R., Muralidhara, S., Kim, H.J. & Dallas, C.E. (1989) Oral toxicity of 1,2-dichloropropane: acute, short-term, and long-term studies in rats. Fundam. appl. Toxicol., 12, 713-730
4. Crebelli, R., Conti, G., Conti, L. & Carere, A. (1984) Induction of somatic segregation by halo-genated aliphatic hydrocarbons in Aspergillus nidulans. Mutat. Res., 138, 33-38
5. De Lorenzo, F., Degl'Innocenti, S., Ruocco, A., Silengo, L. & Cortese, R. (1977) Mutagenicity of pesticides containing 1,3-dichloropropene. Cancer Res., 37, 1915-1917
6. Di Nucci, A., Gregotti, C., Manzo, L., Imbriani, M., Ghittori, S., Bianco, L., Maestri, L. & Capodaglio, E. (1990) 1,2-Dichloropropane hepatotoxicity in rats after inhalation exposure. J. appl. Toxicol., 10, 391-394
7. Galloway, S.M., Armstrong, M.J., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A.D., Nakamura, F., Ahmed, M. & Duk, S. (1987) Chromosome aberrations and sister chromatid exchanges in Chinese hamster ovary cells: evaluations of 108 chemicals. Environ. mol. Mutagen., 10, 1-175
8. Guengerich, F.P., Kim, D.H. & Iwasaki, M. (1991) Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects. Chem. Res. Toxicol., 4, 168-179
9. Haworth, S., Lawlor, T., Mortelmans, K., Speck, W. & Zeiger, E. (1983) Salmonella mutagenicity test results for 250 chemicals. Environ. Mutagen., 5, 1-142
10. IARC (1986) IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 41, Some Halogenated Hydrocarbons and Pesticides Exposures, Lyon, pp. 131-147
11. IARC (1987) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Supplement 7, Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42, Lyon, p. 62
12. Imberti, R., Calabrese, S.R., Emilio, G., Marchi, L. & Giuffrida, L. (1987) Acute poisoning with solvents: chlorinated aliphatic hydrocarbons. Minerva Anestesiol., 53, 399-403 (in Italian)
13. Imberti, R., Mapelli, A., Colombo, P., Richelmi, P., Berte, F. & Bellomo, G. (1990) 1,2-Dichloropropane (DCP) toxicity is correlated with DCP-induced glutathione (GSH) depletion and is modulated by factors affecting intracellular GSH. Arch. Toxicol., 64, 459-465
14. Kirk, H.D., Berdasco, N.M., Breslin, W.J. & Hanley, T.R., Jr (1995) Developmental toxicity of 1,2-dichloropropane (PDG) in rats and rabbits following oral gavage. Fundam. appl. Toxicol., 28, 18-26
15. Linnett, S.L., Clark, D.G., Blair, D. & Cassidy, S.L. (1988) Effects of subchronic inhalation of D-D (1,3-dichloropropene/1,2-dichloropropane) on reproduction in male and female rats. Fundam. appl. Toxicol., 10, 214-223
16. Lucantoni, C., Grottoli, S. & Gaetti, R. (1992) 1,2-Dichloropropane is a renal and liver toxicant [Letter to the Editor]. Toxicol. appl. Pharmacol., 117, 133
17. Principe, P., Dogliotti, E., Bignami, M., Crebelli, R., Falcone, E., Fabrizi, M., Conti, G. & Comba, P. (1981) Mutagenicity of chemicals of industry and agricultural relevance in Salmonella, Streptomyces and Aspergillus. J. Sci. Food Agric., 32, 826-832
18. Stolzenberg, S.J. & Hine, C.H. (1980) Mutagenicity of 2- and 3-carbon halogenated compounds in the Salmonella/mammalian-microsome test. Environ. Mutagen., 2, 59-66
19. 14C]1,2-dichloropropane following oral and inhalation exposure in Fischer 344 rats. Toxicology, 68, 291-306
20. Trevisan, A., Rizzi, E., Bungaro, A., Pozzoben, L., Gioffre, F., Scapinello, A., Valeri, A. & Chiesura, P. (1988) Proximal tubule brush boarder angiotensin converting enzyme behaviour and nephrotoxicity due to 1,2-dichloropropane. Arch. Toxicol., Suppl. 12, 190-192
21. Trevisan, A., Rizzi, E., Scapinello, A., Gioffre, F. & Chiesura, P. (1989) Liver toxicity due to 1,2-dichloropropane in the rat. Arch. Toxicol., 63, 445-449
22. Trevisan, A., Troso, O. & Maso, S. (1991) Recovery of biochemical changes induced by 1,2-dichloropropane in rat liver and kidney. Hum. exp. Toxicol., 10, 241-244
23. Trevisan, A., Meneghetti, P., Maso, S. & Troso, O. (1993) In vitro mechanisms of 1,2-dichloropropane nephrotoxicity using the renal cortical slice model. Hum. exp. Toxicol., 12, 117-121
24. von der Hude, W., Scheutwinkel, M., Gramlich, U., Fissler, B. & Basler, A. (1987) Genotoxicity of three-carbon compounds evaluated in the SCE test in vitro. Environ. Mutagen., 9, 401-410
25. Woodruff, R.C., Mason, J.M., Valencia, R. & Zimmering, S. (1985) Chemical mutagenesis testing in Drosophila. V. Results of 53 coded compounds tested for the National Toxicology Program. Environ. Mutagen., 7, 677-702