Graft-versus-myeloma after withdrawal of immunosuppression following allogeneic peripheral stem cell transplantation

Bone Marrow Transplantation

Volumn 24, Issue 8, 1999, Pages 925-927

  Libura, J ^b   Hoffmann, T ^b   Passweg, J R ^a   Gregor, M ^b   Favre, G ^b   Tichelli, A ^b   Gratwohl, A ^b  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b NONE

Author keywords

Allogeneic stem cell transplantation; Graft versus leukemia; Graft versus myeloma; Multiple myeloma

Indexed keywords

IMMUNOSUPPRESSIVE AGENT;

ADULT; ARTICLE; CASE REPORT; DRUG WITHDRAWAL; FEMALE; GRAFT VERSUS HOST REACTION; GRAFT VERSUS LEUKEMIA EFFECT; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; MULTIPLE MYELOMA; PRIORITY JOURNAL; REMISSION; STEM CELL TRANSPLANTATION;

EID: 0032726713     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1701980     Document Type: Article

References (19)

1. Horowitz MM, Gale RP, Sondel PM et al. Graft-versus-leukemia reactions after bone marrow transplantation. Blood 1990; 75: 555-562.
2. Collins RH, Shpilberg O, Drobyski WR et al. Donor leukocyte infusions in 140 patients with relapsed malignancy after allogenic bone marrow transplantation. J Clin Oncol 1997; 15: 433-444.
3. Kolb HJ, Holler E. Adoptive immunotherapy with donor lymphocyte transfusions. Curr Opin Oncol 1997; 9: 139-145.
4. Collins RH, Rogers ZR, Bennett M et al. Hematologic relapse of chronic myelogenous leukemia following allogeneic bone marrow transplantation: apparent graft-versus-leukemia effect following abrupt discontinuation of immunosupression. Bone Marrow Transplant 1992; 10: 391-395.
5. Kolb HJ, Mittermueller J, Hertenstein H et al. Adoptive immunotherapy in human and canine chimeras - the role of interferon alfa, EBMT Chronic Leukemia Working Party. Semin Hematol 1993; 30 (Suppl. 3): 37-39.
6. Bjorkstrand B, Ljungman P, Svensson H et al. Allogeneic bone marrow transplantation in multiple myeloma: a retrospective case-matched study from the European Group for Blood and Marrow Transplantation. Blood 1996; 12: 4711-4718.
7. Tricot G, Vesole DH, Jagannath S et al. Graft-versus-myeloma effect: proof of principle. Blood 1996; 87: 1196-1198.
8. Mehta J, Singhal S. Graft-versus-myeloma. Bone Marrow Transplant 1998; 22: 835-843.
9. Verdonck LF, Lokhorst HM, Dekker AW et al. Graft-versus-myeloma effect in two cases. Lancet 1996; 347: 800-801.
10. Aschan J, Lonnqvist B, Ringden O et al. Graft versus myeloma effect. Lancet 1996; 348: 346.
11. Lokhorst HM, Schattenberg A, Cornelissen JJ et al. Donor leukocyte infusions are effective in relapsed multiple myeloma after bone marrow transplantation. Blood 1997; 90: 4206-4211.
12. Orsini E, Alyea EP, Schlossman RJ et al. Expansion of preexisting clonal populations following donor lymphocyte infusion for relapsed multiple myeloma after allogeneic bone marrow transplantation. Blood 1997; 90 (Suppl. 1): 549a.
13. Glass B, Majolino I, Dreger P et al. Allogeneic peripherial blood progenitor cells for treatment of relapse after bone marrow transplantation. Bone Marrow Transplant 1997; 20: 533-541.
14. Barlogie B, Smith L, Alexanian R. Effective treatment of advanced multiple myeloma refractory to alkylating agents. New Engl J Med 1984; 310: 1353-1356.
15. Blade J, Samson D, Reece D et al. Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Br J Haematol 1998; 102: 1115-1123.
16. JR Passweg, A Gratwohl, A Tichelli et al. 25 Jahre Allogene Knochenmarks-transplantation in Basel: 1973-1998. Schweizerische Medizinische Wochenschrift 1998; 128: 1568-1574.
17. Gratwohl A, Hermans J, van Biezen A et al. Delayed and divergent effects of anti-Hy minor histocompatibilty antigen reactivity after allogeneic BMT for CML. Blood 1998; 92 (Suppl. 1): 320a (Abstr. 1312).
18. Petersen FB, Appelbaum FR, Bigelow CL et al. High-dose cytosine arabinoside, total body irradiation and marrow transplantation for advanced malignant lymphoma. Bone Marrow Transplant 1989; 4: 483-488.
19. Abraham R, Szer J, Bardy P et al. Early cyclosporine taper in high-risk sibling allogeneic bone marrow transplants. Bone Marrow Transplant 1997; 20: 773-777.