Zn2+ modulation of neuronal transient K+ current: Fast and selective binding to the deactivated channels

Biophysical Journal

Volumn 77, Issue 5, 1999, Pages 2552-2562

  Kuo, Chung Chin ^a,b   Chen, Fang Ping ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; NICKEL; POTASSIUM CHANNEL; POTASSIUM ION; SODIUM CHANNEL; SODIUM ION; ZINC; POTASSIUM; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN SLICE; CONCENTRATION RESPONSE; CONTROLLED STUDY; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; RAT; ANIMAL; CHANNEL GATING; DOSE RESPONSE; DRUG EFFECT; ELECTRIC CONDUCTIVITY; ENZYME SPECIFICITY; KINETICS; METABOLISM; NERVE CELL; PROTEIN BINDING;

ANIMALIA;

ANIMALS; CADMIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC CONDUCTIVITY; ION CHANNEL GATING; KINETICS; NEURONS; POTASSIUM; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN BINDING; RATS; SUBSTRATE SPECIFICITY; ZINC;

EID: 0032726349     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(99)77090-6     Document Type: Article

References (39)

1. Aniksztejn, L., G. Charton, and Y. Ben-Ari. 1987. Selective release of endogenous zinc from the hippocampal mossy fibers in situ. Brain Res. 404:58-64.
2. 2+ from brain tissue during activity. Nature. 308:734-736.
3. Bardoni, R., and O. Belluzzi. 1994. Modifications of A-current kinetics in mammalian central neurons induced by extracellular zinc. J. Physiol. (Lond). 479:389-401.
4. Beaulieu, C., R. Dyck, and M. Cynadar. 1992. Enrichment of glutamate in zinc-containing terminals of the cat visual cortex. Neuroreport. 3:861-864.
5. Berg, H. C. 1983. Random Walks in Biology. Princeton University Press, Princeton, NJ.
6. Berg, J. M., and H. A. Godwin. 1997. Lessons from zinc-binding peptides. Annu. Rev. Biophys. Biomol. Struct. 26:357-371.
7. + channel are not essential for channel activity or zinc modulation. Biophys. J. 66:694-699.
8. + channels. Proc. Natl. Acad. Sci. USA. 88:5092-5095.
9. Cowan, J. A. 1997. Fundamentals of inorganic biochemistry. In Inorganic Biochemistry: An Introduction. J. A. Cowen, editor. Wiley-VCH, New York. 1-63.
10. 2+. Can. J. Physiol. Pharmacol. 73:36-42.
11. Faber, H., K. Braun, W. Zuschratter, and H. Scheich. 1989. System specific distribution of zinc in the chick brain: a light and electron-microscopic study using the Timm method. Cell Tissue Res. 258:247-257.
12. Frederickson, C. J. 1989. Neurobiology of zinc and zinc-containing neurons. Int. Rev. Neurobiol. 131:145-238.
13. Frederickson, C. J., M. A. Klitenick, W. I. Manton, and J. B. Kirkpatrick. 1983. Cytoarchitectonic distribution of zinc in the hippocampus of man and the rat. Brain Res. 273:335-339.
14. Gooddy, W., E. I. Hamilton, and T. R. Williams. 1975. Spark-source mass spectrometry in the investigation of neurological disease. II. Element levels in brain, cerebrospinal fluid and blood: some observations on their abundance and significance. Brain. 98:65-70.
15. Gooddy, W., T. R. Williams, and D. Nicholas. 1974. Spark-source mass spectrometry in the investigation of neurological disease. I. Multielement analysis in blood and cerebrospinal fluid. Brain. 97:327-336.
16. Harrison, N. L., H. K. Radke, G. Talukder, and J. M. H. Ffrench-Mullen. 1993. Zinc modulates transient outward current gating in hippocampal neurons. Receptors Channels. 1:153-163.
17. Haug, F. M. S. 1967. Electron microscopical localization of the zinc in hippocampal mossy fibre synapses by a modified sulphide silver procedure. Histochemie. 8:355-368.
18. Hess, P., and R. W. Tsien. 1984. Mechanism of ion permeation through calcium channels. Nature. 309:453-456.
19. Hille, B. 1992. Potassium channels and chloride channels. In Ionic Channels of Excitable Membranes. B. Hille, editor. Sinauer Associates, Sunderland, MA. 116-121.
20. Hoshi, T., W. N. Zagotta, and R. W. Aldrich. 1991. Two types of inactivation in Shaker potassium channels: effects of alterations in the carboxy-terminal region. Neuron. 7:547-556.
21. Howell, G. A., M. G. Welch, and C. J. Frederickson. 1984. Stimulation-induced uptake and release of zinc in hippocampal slices. Nature. 308:736-738.
22. Huang, R.-C., Y.-W. Peng, and K.-W. Yau. 1993. Zinc modulation of a transient potassium current and histochemical localization of metal in neurons of the suprachiasmatic nucleus. Proc. Natl. Acad. Sci. USA. 90:11806-11810.
23. + current: an external open-channel blocker preventing fast inactivation. Biophys. J. 12: 2845-2857.
24. 2+ channel pore in rat phaeochromocytoma cells. J. Physiol. (Lond.). 466:657-682.
25. + channel during gating. Neuron. 16:859-867.
26. Lopez-Barneo, H., T. Hoshi, S. H. Heinemann, and R. W. Aldrich. 1993. Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels. Receptors Channels. 1:61-71.
27. Nieboer, E., and G. G. Fletcher. 1996. Determinants of reactivity in metal toxicology. In Toxicology of Metals. L. W. Chang, editor. CRC Press, Boca Raton, FL. 113-132.
28. Ogielska, E. M., W. N. Zagotta, T. Hoshi, S. H. Heinemann, J. Haab, and R. W. Aldrich. 1995. Cooperative subunit interactions in C-type interaction of K channels. Biophys. J. 69:2449-2457.
29. Palm, R., and G. Hallmans. 1982. Zinc concentrations in the cerebrospinal fluid of normal adults and patients with neurological diseases. J. Neurol. Neurosurg. Psychiatry. 45:685-690.
30. Perez-Clausell, J. 1996. Distribution of terminal fields stained for zinc in the neocortex of the rat. J. Chem. Neuroanat. 11:99-111.
31. Perez-Clausell, J., and G. Danscher. 1986. Intravesicular localization of zinc in rat telencephalic boutons. A histochemical study. Brain Res. 337:91-98.
32. Slomianka, L. 1992. Neurons of origin of zinc-containing pathways and the distribution of zinc-containing boutons in the hippocampal region of the rat. Neuroscience. 48:325-352.
33. Spires, S., and T. Begenisich. 1992. Chemical properties of the divalent cation binding site on potassium channels. J. Gen. Physiol. 100: 181-193.
34. Spires, S., and T. Begenisich. 1994. Modulation of potassium channel gating by external divalent cations. J. Gen. Physiol. 104:675-692.
35. Talukder, G., and N. L. Harrison. 1995. On the mechanism of modulation of transient outward current in cultured rat hippocampal neurons by diand trivalent cations. J. Neurophysiol. 73:73-79.
36. Vallee, B. L., and D. S. Auld. 1990. Zinc coordination, function, and structure of zinc enzymes and other proteins. Biochemistry. 29: 5647-5659.
37. Williams, R. J. P. 1989. An introduction to the biochemistry of zinc. In Zinc in Human Biology. C. F. Mills, editor. Springer-Verlag, Berlin. 15-31.
38. Wooltorton, J. R. A., and A. Mathie. 1993. Block of potassium currents in rat isolated sympathetic neurons by tricyclic antidepressants and structurally related compounds. Br. J. Pharmacol. 110:1126-1132.
39. 2+ channels. Nature. 366:158-161.