Naphthalene-induced cataract model in rats: A comparative study between slit and retroillumination images, biochemical changes and naphthalene dose and duration

Current Eye Research

Volumn 19, Issue 5, 1999, Pages 418-425

  Holmén, Jörgen B ^a,b   Ekesten, Björn ^a   Lundgren, Björn ^b  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b Pharmacia and Upjohn AB ^*  (Sweden)

Author keywords

Cataract; Naphthalene; NIDEK EAS 1000 camera; Rat

Indexed keywords

LENS PROTEIN; NAPHTHALENE; POTASSIUM; SODIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATARACT; CATARACTOGENESIS; COMPARATIVE STUDY; CONTROLLED STUDY; EYE PHOTOGRAPHY; FEMALE; LENS; LIGHT SCATTERING; NONHUMAN; OSMOSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; TISSUE LEVEL;

ANIMALS; CATARACT; CATIONS; CRYSTALLINS; DIAGNOSTIC IMAGING; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; LENS, CRYSTALLINE; NAPHTHALENES; RATS; RATS, INBRED BN; TIME FACTORS;

EID: 0032725951     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1076/ceyr.19.5.418.5296     Document Type: Article

References (19)

1. Zigler Jr JS. Animal models for the study of maturity-onset and hereditary cataract. Exp Eye Res. 1990;50:651-657.
2. Adams DR. The nature of the ocular lesions produced experimentally by naphthalene. Br J Ophthalmol. 1930; 14:49-60.
3. Bouchard CJ, Charrin A. La cataracte produite par la naphtaline. C.R. Seances Soc Biol Ses Fil. 1886;8:614-615.
4. van Heyningen R, Pirie A. The metabolism of naphthalene and its toxic effect on the eye. Biochem J. 1967;102: 842-852.
5. Kojima M. Enzymatic distribution patterns of rat lenses and the changes that occur during naphthalene cataract development. Ophthalmic Res. 1992;24:73-82.
6. Murano H, Kojima M, Sasaki K. Differences in naphthalene cataract formation between albino and pigmented rat eyes. Ophthalmic Res. 1993;25:16-22.
7. Nagata M, Murano H, Kojima M, Sasaki K. A mild progression type of naphthalene-induced cataract in brown-Norway rats. Ophthalmic Res. 1995;1:34-38.
8. Bours J, Ahrend MHJ, Wegener A. Influence of Phakan® on the toxicity of naphthalene in rat lenses, analyzed by isoelectric focusing of single lens layers. Ocular Toxicol. 1995:197-203.
9. Gupta PP, Pandey DJ, Sharma AL, Srivastava RK, Mishra SS. Prevention of experimental cataract by alpha-tocopherol. Indian J Exp Biol. 1984;22:620-622.
10. Hockwin O, Wegener A, Sisk DR, Dohrmann B, Kruse M. Efficacy of AL-1576 in preventing naphthalene cataract in three rat strains. A slit lamp and Scheimpflug photographic study. Lens Res. 1985;2:321-335.
11. Tao RV, Holleschau AM, Rathbun WB. Naphthalene-induced cataract in the rat. II. Contrasting effects of two aldose reductase inhibitors on glutathione and glutathione redox enzymes. Ophthalmic Res. 1991;23:272-283.
12. Kawara T, Obazawa H. A new method for retroillumination photography of cataractous lens opacities. Am J Ophthalmol. 1980;90:186-189.
13. Vivino MA, Mahurkar A, Trus B, Lopez ML, Datiles M. Quantitative analysis of retroillumination images. Eye. 1995;9:77-84.
14. Kojima M, Sasaki K. Application of a new Scheimpflug camera (EAS-1000) to animal cataract models. Ophthalmic Res. 1992;1:3-9.
15. Sakamoto Y, Sasaki K, Nakamura Y, Watanabe N. Reproducibility of data obtained by a newly developed anterior eye segment analysis system, EAS-1000. Ophthalmic Res. 1992;1:10-20.
16. Duncan G, Williams MR, Riach RA. Calcium, cell signalling and cataract. In Progress in Retinal and Eye Research. Elsevier Science Ltd, 1994:623-652.
17. Duncan G, Bushell AR. Ion analyses of human cataractous lenses. Exp Eye Res. 1975;20:223-30.
18. Boutros G, Koch HR, Jansen R, Jacob TJ, Duncan G. Effect of 8-methoxypsoralen on rat lens cations, membrane potential and protein levels. Exp Eye Res. 1984;38: 509-513.
19. Wegener A, Pelser M, Ringens C, Hockwin O. Monitoring naphthalene cataracts of rats after topical application of AL-1576 eye drops with the TOPCON SL-45. Test for dose-effect relation. Lens Res. 1988;5:117-127.