Preischemic and postischemic treatment with a new Na+/H+-exchange inhibitor, FR183998, shows cardioprotective effects in rats with cardiac ischemia and reperfusion

Journal of Cardiovascular Pharmacology

Volumn 34, Issue 6, 1999, Pages 848-856

  Ohara, Fumihiro ^a   Sugimoto, Toshiko ^a   Yamamoto, Nobuhiro ^a   Ohkubo, Kazumi ^a   Maeda, Kazuhiro ^a   Ozaki, Toru ^a   Seki, Jiro ^a   Goto, Toshio ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Arrhythmia; Ischemia; Myocardial infarction; Na+ H+exchange; Rat hearts; Reperfusion

Indexed keywords

5 (2,5 DICHLOROTHIENYL) 3 (2 DIMETHYLAMINOETHYLCARBAMOYL)BENZOYLGUANIDINE; 5 (2,5 DICHLOROTHIOPHEN 3 YL) 3 [(2 DIMETHYLAMINOETHYL) CARBAMOYL] BENZOYLGUANIDINE; SODIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DRUG EFFECT; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEART VENTRICLE FIBRILLATION; HUMAN; HUMAN CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; RAT; REPERFUSION INJURY;

ANESTHESIA; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIA; BLOOD PRESSURE; ENZYME INHIBITORS; HEART RATE; HUMANS; HYDROGEN-ION CONCENTRATION; LYMPHOCYTES; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SODIUM-HYDROGEN ANTIPORTER;

EID: 0032725465     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199912000-00012     Document Type: Article

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