Three new active cisplatin-containing combinations in the neoadjuvant treatment of locally advanced and locally recurrent breast carcinoma: A randomized phase II trial

Breast Cancer Research and Treatment

Volumn 56, Issue 2, 1999, Pages 125-132

  Cocconi, Giorgio ^a,b   Bisagni, Giancarlo ^a   Ceci, Guido ^a   Di Blasio, Beatrice ^a   De Lisi, Vincenzo ^a   Passalacqua, Rodolfo ^a   Zadro, Alvise ^a   Boni, Corrado ^a   Morandi, Paolo ^a   Savoldi, Luisa ^a  

^a Ital Oncol Grp Clin Res GOIRC   (Italy)

^b UNIVERSITY HOSPITAL OF PARMA   (Italy)

Author keywords

Breast carcinoma; Cisplatin; Loco regional recurrence; Primary chemotherapy; Stage III

Indexed keywords

CISPLATIN; EPIRUBICIN; ETOPOSIDE; FOLINIC ACID; METHOTREXATE; MITOMYCIN C; VINCRISTINE;

ADULT; ADVANCED CANCER; AGED; ARTICLE; BLOOD TOXICITY; BREAST CARCINOMA; CANCER ADJUVANT THERAPY; CANCER COMBINATION CHEMOTHERAPY; CANCER RECURRENCE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GASTROINTESTINAL SYMPTOM; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MUCOSA INFLAMMATION; NEPHROTOXICITY; NEUROTOXICITY; ORAL DRUG ADMINISTRATION; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

EID: 0032725127     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1006246012448     Document Type: Article

References (31)

1. Willes RE, Adrianza ME, Parsons B, Felix J, Marsoni S: Compilation of phase II results with single antineoplastic agents. Cancer Treat Symposia 4: 1-477, 1985
2. Kolaric K, Roth A: Phase II clinical trial of cisdichlorodiammine platinum (Cis-DDP) for antitumorigenic activity in previously untreated patients with metastatic breast cancer. Cancer Chemother Pharmacol 11: 108-112, 1983
3. Sledge GW Jr., Loehrer PJ Sr., Roth BJ, Einhom LH: Cisplatin as first-line therapy for metastatic breast cancer. J Clin Oncol 6: 1811-1814, 1988
4. Peters WP, Jones RB, Vredenburgh J, Shpall EJ, Hussein A, Elkordy M, Rubin P, Ross M, Berry D: A large prospective, randomized trial of high-dose combination alkylating agents (CPB) with autologous cellular support (ABMS) as consolidation for patients with metastatic breast cancer achieving complete remission after intensive doxorubicin-based induction therapy (AFM). 'Abstract'. Proceed ASCO 15: 149, 1996
5. Cocconi G, Bisagni G, Bacchi M, Boni C, Bartolucci R, Ceci G, Colozza MA, De Lisi V, Lottici R, Mosconi AM, Passalacqua R, Tonato M: Cisplatin and etoposide as first-line chemotherapy for metastatic breast carcinoma: a prospective randomized trial of the Italian Oncology Group for Clinical Research. J Clin Oncol 9: 664-669, 1991
6. Roth BJ, Sledge GW Jr., Williams SD, Meyer SC, Ansari R, Fisher WB: Methotrexate, vinblastine, doxorubicin, and cisplatin in metastatic breast cancer. A phase II trial of the Hoosier Oncology Group. Cancer 68: 248-252, 1991
7. Bisagni G, Cocconi G, Ceci G, De Lisi V, Di Blasio B, Lottici R, Passalacqua R, Finardi C: M-VAC combination in locally advanced, locally recurrent or metastatic breast carcinoma. A phase II study. Ann Oncol 5: 93-94, 1994
8. Langer CJ, Catalano R, Weiner LM, Scher R, Bagchi P, Saren B, Comis RL: Phase II evaluation of methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) in advanced, measurable breast carcinoma. Cancer Investigation 13: 150-159, 1995
9. American Joint Committee on Cancer: Manual for Staging of Cancer. Fourth edn J.B. Lippincott Company, Philadelphia, 1992, pp. 149-154
10. Reeth A, Hayes DF: Specific sites and emergencies: local recurrence. In: Harris JR, Helmann S, Henderson CC et al. (eds). Breast Disease (2nd edn). Lippincott Philadelphia, PA, 1991, pp 527-540
11. Oken MM, Creech RH, Tormey DC, Horton J, Davis TE, McFadden ET, Carbone PP: Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 5: 649-655, 1982
12. Miller AB, Hoogstraten B, Staquet M, Winker A: Reporting results or cancer treatment. Cancer 47: 207-214, 1981
13. Cocconi G, Di Blasio B, Alberti G, Bisagni G, Botti E, Peracchia G: Problems in evaluating response of primary breast cancer to systemic therapy. Breast Cancer Res Treat 4: 309-313, 1984
14. Miles DW, Fogarty O, Ash CM, Rudd RM, Trask CWL, Spiro SG, Gregory WM, Ledermann JA, Souhami RL, Harper PG: Received dose-intensity: a randomized trial of weekly chemotherapy with and without granulocyte colony-stimulating factor in small-cell lung cancer. J Clin Oncol 12: 77-82, 1994
15. Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Ass 53: 457-481, 1958
16. Bartelink H, Rubens RD, van der Schueren E and Sylvester R: Hormonal therapy prolongs survival in irradiated locally advanced breast cancer: a European Organization for Research and Treatment of Cancer randomized phase III trial. J Clin Oncol 15: 207-215, 1997
17. Booser DJ, Hortobagyi GN: Treatment of locally advanced breast cancer. Seminars in Oncology 19: 278-285, 1992
18. Valagussa P, Zambelli M, Bonadonna G, Zucali R, Mezzanotte G, Veronesi U: Prognostic factors in locally advanced noninflammatory breast cancer. Long-term results following primary chemotherapy. Breast Cancer Res Treat 15: 137-147, 1990
19. Patanaphan V, Salazar OM, Poussin-Rosillo H: Prognosticators in recurrent breast cancer: a 15-year experience with irradiation. Cancer 54: 228-234, 1984.
20. Blumenschein GR, Pinnamanemi K, Budzar AU, Hortobagyi GN, Yap H, Montague ED, Ames FC: Combined regional and systemic therapy in breast cancer patients with an isolated metastases with or without chemotherapy. In: Orlando, Jones SE, Salmon SE (eds). Adjuvant Therapy of Cancer IV. Grune and Stratton, New York, 1984, pp 311-318
21. Borner M, Bacchi M, Goldhirsch A, Greiner R, Harder F, Castiglione M, Jungi WF, Thürlimann B, Cavalli F, Obrecht JP, Leyvraz S, Alberto P, Adam H, Varini M, Loehnert T, Senn HJ, Metzger U, Brunner K: First isolated locoregional recurrence following mastectomy for breast cancer: results of a phase III multicenter study comparing systemic treatment with observation after excision and radiation. J Clin Oncol 12: 2071-2077, 1994
22. Goldhirsh A, Gelber RD and Castiglione M: Relapse of breast cancer after adjuvant treatment in premenopausal and perimenopausal women: patterns and prognoses. J Clin Oncol 6: 89-97, 1988
23. Fisher B, Brown A, Mamounas E, Wieand S, Fisher E, Robidoux A, Margolese R, Cruz A, Wickerham DL, Wolmark N: Effect of preoperative therapy for primary breast cancer on local-regional disease, disease-free survival and survival: results from NSABP B-18. 'Abstract'. Proceed ASCO 16: 127a, 1997
24. De Lena M, Varini M, Zucali R, Rovini D, Viganotti G, Valagussa P, Veronesi U, Bonadonna G: Multimodal treatment for locally advanced breast cancer. Cancer Clin Trials 4: 229-236, 1981
25. Perloff M, Lesnick GJ, Korzun A, Chu F, Holland JF, Thirlwell MP, Ellison RR, Carey RW, Leone L, Weinberg V, Rice MA, Wood WC: Combination chemotherapy with mastectomy or radiotherapy for stage III breast carcinoma: a Cancer and Leukemia Group B study. J Clin Oncol 6: 261-269, 1988
26. Herrada J, Iyer RB, Atkinson EN, Sneige N, Buzdar AU, Hortobagyi GN: Relative value of physical examination, mammography, and breast sonography in evaluating the size of the primary tumor and regional lymph node metastases in women receiving neoadjuvant chemotherapy for locally advanced breast carcinoma. Clinical Cancer Research 3: 1565-1569, 1997
27. Hortobagyi GN, Ames FC, Budzar AU, Kau SW, McNeese MD, Paulus D, Hug V, Holmes FA, Romsdahl MM, Fraschini G, McBride CM, Martin RG, Montague E: Management of stage III primary breast cancer with primary chemotherapy, surgery, and radiation therapy. Cancer 62: 2507-2516, 1988
28. Swain SM, Sorace RA, Bagley CS, Danforth DN Jr, Bader J, Wesley MN, Steiberg SM, Lippman ME: Neoadjuvant chemotherapy in the combined modality approach of locally advanced non metastatic breast cancer. Cancer Res 47: 3889-3894, 1987
29. Hoogstraten B, Gad-el-Mawla N, Maloney TR, Fletcher WS, Vaughn CB, Tranum BL, Athens JW, Costanzi JJ, Foulkes M: Combined modality therapy for first recurrence of breast cancer: a Southwest Oncology Group Study. Cancer 54: 2248-2256, 1984.
30. Piccart MJ, De Valeriola D, Paridaens R, Balikdjian D, Mattheiem WH, Loriaux C, Arrigo C, Cantraine F, Heuson J: Six-year results of a multimodality treatment strategy for locally advanced breast cancer. Cancer 62: 2501-2506, 1988
31. Wieson RE: Surgical management of locally advanced and recurrent breast cancer. Cancer 53: 752-757, 1984