Synthesis and evaluation of a new fluorine-18 labeled rotenoid as a potential pet probe of mitochondrial complex I activity

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 42, Issue 11, 1999, Pages 1039-1051

  Martarello, Laurent ^a,b   Greenamyre, J Timothy ^b   Goodman, Mark M ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Complex I (NADH: ubiquinone oxidoreductase); Parkinson's disease; PET; Radiofluorine; Rotenone

Indexed keywords

FLAVONOIDS; FLUORINE;

COMPLEX I (NADH: UBIQUINONE OXIDOREDUCTASE); FLUORINE-18; MITOCHONDRIAL COMPLEX; OXIDO-REDUCTASES; PARKINSON'S DISEASE; PET PROBE; RADIOFLUORINE; ROTENOIDS; ROTENONE; UBIQUINONE;

PROBES;

12 DEOXO 6'7' DIHYDRO 7' FLUOROTENONE; FLUORINE 18; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; ENZYME ACTIVITY; HEART; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOCHEMISTRY; RAT; SYNTHESIS;

ANIMALIA;

EID: 0032724590     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1344(199911)42:11<1039::AID-JLCR259>3.0.CO;2-1     Document Type: Article

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