Health risk above the reference dose for multiple chemicals

Regulatory Toxicology and Pharmacology

Volumn 30, Issue 2 II, 1999, Pages

  Teuschler, Linda K ^a   Dourson, Michael L ^b   Stiteler, William M ^c   McClure, Peter ^c   Tully, Heather ^c  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b Toxicology Excellence for Risk Assessment   (United States)

^c SYRACUSE RESEARCH CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMPYLATE; DISULFOTON; THIOCARBAMIC ACID DERIVATIVE;

CHEMICAL ANALYSIS; CONFERENCE PAPER; ENVIRONMENTAL EXPOSURE; HEALTH HAZARD; HUMAN; NONHUMAN; PRIORITY JOURNAL; RISK ASSESSMENT; TOXICITY TESTING;

EID: 0032723926     PISSN: 02732300     EISSN: None     Source Type: Journal    
DOI: 10.1006/rtph.1999.1321     Document Type: Conference Paper

References (18)

1. Barnes, D. G., and Dourson, M. L. (1988). Reference dose (RfD): Description and use in health risk assessment. Reg. Toxicol. Pharmacol. 8, 471-486.
2. Chappell, W. R. (1989). Interspecific scaling of toxicity data: A question of interpretation. Risk Anal. 9(1), 13-14.
3. Davies, D. B., and Holub, B. J. (1980). Toxicological evaluation of dietary diazinon in the rat. Arch. Environ. Toxicol. 9, 637-650.
4. Derosa, C. T., Stara, J., and Durkin, P. (1985). Ranking chemicals based on toxicity data. Toxicol. Ind. Heath 1, 177-199.
5. Dourson, M. L., Hertzberg, R., Hartung, R., and Blackburn, K. (1985). Novel methods for the estimation of acceptable daily intake. Toxicol. Ind. Health 1(4), 23-33.
6. Dourson, M. L., Teuschler, L. K., Durkin, P. R., and Stiteler, W. M. (1997). Categorical regression of toxicity data: A case study using aldicarb. Reg. Toxicol. Pharmacol. 25, 121-129.
7. Farland, W., and Dourson, M. L. (1992). Noncancer health endpoints: Approaches to quantitative risk assessment. In Comparative Environmental Risk Assessment (R. Cothern, Ed.), Lewis, Boca Raton.
8. Guth, D. J., Jarabek, A. M., Wymer, L., and Hertzberg, R. C. (1991). Evaluation of Risk Assessment Methods for Short-Term Inhalation Exposure. Presented at the 84th Annual Meeting of the Air and Waste Management Association, Vancouver, British Columbia, June 16-21.
9. Guth, D. J. (1996). Acute Exposure Response Assessment for 1,1,1-Trichloroethane Using Stratified Ordinal Regression. Presented at the 89th Annual Meeting of the Air and Waste Management Association, Nashville, TN, June 23-28.
10. Guth, D. J., Carroll, R. J., Simpson, D. G., and Zhou, H. (1997). Categorical regression analysis of acute exposure to tetrachloroethylene. Risk Anal. 17(3), 321-332.
11. Hazelton Laboratories (1955). Unpublished study submitted by Ciba-Geigy to U.S. Environmental Protection Agency (chronic feeding-rat), MRID No. 75932. [Cited in U.S. EPA, 1986]
12. Hertzberg, R. C. (1989). Extrapolation and scaling of animal data to humans: Fitting a model to categorical response data with application to species extrapolation of toxicity. Health Phys. 57(Suppl. 1), 405-409.
13. Hertzberg, R. C., and Miller, M. (1985). A statistical model for species extrapolating using categorical response data. Toxicol. Ind. Health 1(4), 43-63.
14. Jarabek, A. M., Menache, M. G., Overton, J. H., Jr., Dourson, M. L., and Miller, F. J. (1990). The U.S. Environmental Protection Agency's inhalation RfD methodology: Risk assessment for air toxics. Toxicol. Ind. Health 6(5), 279-301.
15. Lu, F. C., and Sielken, R. L. (1991). Assessment of safety/risk of chemicals: Inception and evolution of the ADI and dose-response modeling procedures. Toxicol. Lett. 59, 5-40.
16. PPG Industries, Inc. (1985). Effect of EPTC on Pregnancy of the Rabbit, MRID No. 00161599. Available from EPA.
17. Rao, V. R., Levy, K., and Lustik, M. (1993). Logistic regression of inhalation toxicities of perchloroethylene - Application in noncancer risk assessment. Reg. Toxicol. Pharmacol. 18, 233-247.
18. SAS Institute, Inc. (1990). Cary, NC.