Involvement of protein kinase C in Rickettsia rickettsii-induced transcriptional activation of the host endothelial cell

Infection and Immunity

Volumn 67, Issue 12, 1999, Pages 6418-6423

  Sahni, Sanjeev K ^a,b   Turpin, Loel C ^a   Brown, Tracy L ^a   Sporn, Lee Ann ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BISINDOLYLMALEIMIDE; CALPHOSTIN C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE C; THROMBOPLASTIN;

ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME REGULATION; GENE EXPRESSION REGULATION; HOST CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RICKETTSIA RICKETTSII; ROCKY MOUNTAIN SPOTTED FEVER; SIGNAL TRANSDUCTION; TRANSACTIVATION; TRANSCRIPTION REGULATION;

CELLS, CULTURED; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HUMANS; NAPHTHALENES; NF-KAPPA B; PROTEIN KINASE C; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RICKETTSIA RICKETTSII; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; THROMBOPLASTIN; TRANS-ACTIVATION (GENETICS); UMBILICAL VEINS;

EID: 0032723011     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Bach, R. 1988. Initiation of coagulation by tissue factor. Crit. Rev. Biochem. 23:339-368.
2. Bach, R., R. Gentry, and Y. Nemerson. 1986. Factor VII binding to tissue factor in reconstituted phospholipid vesicles: induction of cooperativity by phosphatidylserine. Biochemistry 25:4007-4020.
3. Bitko, V., and S. Barik. 1998. Persistent activation of RelA by respiratory syncytial virus involves protein kinase C, underphosphorylated IκEBβ, and sequestration of protein phosphatase 2A by the viral phosphoprotein. J. Virol. 72:5610-5618.
4. Clifton, D. R., R. A. Goss, S. K. Sahni, D. vanAntwerp, R. B. Baggs, V. J. Marder, D. J. Silverman, and L. A. Sporn. 1998. NF-κB-dependent inhibition of apoptosis is essential for host cell survival during Rickettsia rickettsii infection. Proc. Natl. Acad. Sci. USA 95:4645-4651.
5. Crespo, P., H. Mischak, and J. S. Gutkind. 1995. Overexpression of mammalian protein kinase C-zeta does not affect the growth characteristics of NIH 3T3 cells. Biochem. Biophys. Res. Commun. 213:266-272.
6. Diaz-Meco, M. T., E. Berra, M. M. Municio, L. Sanz, J. Lozano, I. Dominguez, V. Diaz-Golpe, M. T. Lain de Lera, J. Alcamí, C. V. Payá, F. Arenzana-Seisdedos, J.-L. Virelizier, and J. Moscat. 1993. A dominant negative protein kinase C ζ subspecies blocks NF-κB activation. Mol. Cell. Biol. 13:4770-4775.
7. Diaz-Meco, M. T., I. Dominguez, L. Sanz, P. Dent, J. Lozano, M. M. Municio, E. Berra, R. T. Hay, T. W. Sturgill, and J. Moscat. 1994. ζPKC induces phosphorylation and inactivation of IκB-α in vitro. EMBO J. 13:2842-2848.
8. Drancourt, M., M.-C. Alessi, P.-Y. Levy, I. Juhan-Vague, and D. Raoult. 1990. Selection of tissue-type plasminogen activator and plasminogen activator inhibitor by Rickettsia conorii- and Rickettsia rickettsii-infected cultured endothelial cells. Infect. Immun. 58:2459-2463.
9. Dyer, R. B., C. R. Collaco, D. W. Niesel, and N. K. Herzog. 1993. Shigella flexneri invasion of HeLa cells induces NF-κB DNA-binding activity. Infect. Immun. 61:4427-4433.
10. Gimbrone, M. A., Jr., R. S. Cotran, and J. Folkman. 1974. Human vascular endothelial cells in culture. Growth and DNA synthesis. J. Cell Biol. 60:673-680.
11. Godson, C., B. A. Weiss, and P. A. Insel. 1990. Differential activation of protein kinase C α is associated with arachidonate release in Madin-Darby canine kidney cells. J. Biol. Chem. 265:8369-8372.
12. Han, Y., T. Meng, N. R. Murray, A. P. Fields, and A. R Brasier. 1999. Interleukin-1-induced nuclear factor-κB-IκBα autoregulatory feedback loop in hepatocytes. J. Biol. Chem. 274:939-947.
13. 1 macrophage-like cells. Infect. Immun. 62:2740-2747.
14. 1 macrophages results in a biphasic NF-κB (RelA/p50) activation induced by lipoteichoic acid and bacterial phospholipases and mediated by IκBα and IκBβ degradation. Proc. Natl. Acad. Sci. USA 94:9394-9399.
15. Hobbie, S., L. M. Chen, R. J. Davis, and J. E. Galán. 1997. Involvement of mitogen-activated protein kinase pathways in the nuclear responses and cytokine production induced by Salmonella typhimurium in cultured intestinal epithelial cells. J. Immunol. 159:5550-5559.
16. Huang, F. L., Y. Yoshida, J. R. Cunha-Melo, M. A. Beaven, and K.-P. Huang. 1989. Differential down-regulation of protein kinase C isozymes. J. Biol. Chem. 264:4238-4243.
17. Hug, H., and T. F. Sarre. 1993. Protein kinase C isoenzymes: divergence in signal transduction? Biochem. J. 291:329-343.
18. Ivanov, V., B. Stein, I. Baumann, D. A. E. Dobbelaere, P. Herrlich, and R. O. Williams. 1989. Infection with the intracellular protozoan parasite Theileria parva induces constitutively high levels of NF-κB in bovine T lymphocytes. Mol. Cell. Biol. 9:4677-4686.
19. Kobayashi, E., H. Nakano, M. Morimoto, and T. Tamaoki. 1989. Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun. 159:548-553.
20. Kunsch, C., and C. A. Rosen. 1993. NF-kappa B subunit-specific regulation of the interleukin-8 promoter. Mol. Cell. Biol. 13:6137-6146.
21. Lozano, J., E. Berra, M. M. Municio, M. T. Diaz-Meco, I. Dominguez, L. Sanz, and J. Moscat. 1994. Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase. J. Biol. Chem. 269: 19200-19202.
22. Mackman, N., K. Brand, and T. S. Edgington. 1991. Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THO-1 monocytic cells requires both activator protein 1 and nuclear factor kappa B binding sites. J. Exp. Med. 174:1517-1526.
23. Martiny-Baron, G., M. G. Kazanietz, H. Mischak, P. M. Blumberg, G. Kochs, H. Hug, D. Marmé, and C. Schächtele. 1993. Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976. J. Biol. Chem. 268:9194-9197.
24. Pettersen, K. S., M. T. Wiiger, N. Narahara, K. Andoh, G. Gaudernack, and H. Prydz. 1992. Induction of tissue factor synthesis in human umbilical vein endothelial cells involves protein kinase C. Thromb. Haemostasis 67:473-477.
25. Pitlick, F. A., and Y. Nemerson. 1976. Purification and characterization of tissue factor apoprotein. Methods Enzymol. 45:37-42.
26. Schesser, K., A.-K. Spiik, J.-M. Dukuzumuremyi, M. F. Neurath, S. Pettersson, and H. Wolf-Watz. 1998. The yopJ locus is required for Yersinia-mediated inhibition of NF-κB activation and cytokine expression: YopJ contains a eukaryotic SH2-like domain that is essential for its repressive activity. Mol. Microbiol. 28:1067-1079.
27. Shi, R.-J., P. J. Simpson-Haidaris, V. J. Marder, D. J. Silverman, and L. A. Sporn. 1996. Increased expression of plasminogen activator inhibitor-1 in R. rickettsii-infected endothelial cells. Thromb. Haemostasis 75:600-606.
28. Shi, R.-J., P. J. Simpson-Haidaris, N. B. Lerner, V. J. Marder, D. J. Silverman, and L. A. Sporn. 1998. Transcriptional regulation of endothelial cell tissue factor expression during Rickettsia rickettsii infection: involvement of the transcription factor NF-κB. Infect. Immun. 66:1070-1075.
29. Shimizu, H., K. Mitomo, T. Watanabe, S. Koamoto, and K. Yamamoto. 1990. Involvement of the NF-kappa B-like transcription factor in the activation of the interleukin-6 gene by inflammatory lymphokines. Mol. Cell. Biol. 10: 561-568.
30. Shirakawa, F., and S. B. Mizel. 1989. In vitro activation and nuclear translocation of NF-κB catalyzed by cyclic AMP-dependent protein kinase and protein kinase C. Mol. Cell. Biol. 9:2424-2430.
31. Siebenlist, U., G. Franzoso, and K. Brown. 1994. Structure, regulation and function of NF-κB. Annu. Rev. Cell Biol. 10:405-455.
32. Sporn, L. A., S. O. Lawrence, D. J. Silverman, and V. J. Marder. 1993. E-selectin-dependent neutrophil adhesion to Rickettsia rickettsii-infected endothelial cells. Blood 81:2406-2412.
33. Sporn, L. A., P. J. Simpson-Haidaris, R.-J. Shi, Y. Nemerson, D. J. Silverman, and V. J. Marder. 1994. Rickettsia rickettsii infection of cultured human endothelial cells induces tissue factor expression. Blood 83:1527-1534.
34. Sporn, L. A., and V. J. Marder. 1996. Interleukin-1α production during Rickettsia rickettsii-infection of cultured endothelial cells: potential role in autocrine cell stimulation. Infect. Immun. 64:1609-1613.
35. Sporn, L. A., S. K. Sahni, N. B. Lerner, V. J. Marder, D. J. Silverman, L. C. Turpin, and A. L. Schwab. 1997. Rickettsia rickettsii infection of cultured human endothelial cells induces NF-κB activation. Infect. Immun. 65:2786-2791.
36. Sugiyama, S., K. Kugiyama, N. Ogata, H. Doi, Y. Ota, M. Ohgushi, T. Matsumura, H. Oka, and H. Yasue. 1998. Biphasic regulation of transcription factor nuclear factor-κB activity in human endothelial cells by lysophosphatidylcholine through protein kinase C-mediated pathway. Arterioscler. Thromb. Vasc. Biol. 18:568-576.
37. Tang, P., C. L. Sutherland, M. R. Gold, and B. B. Finlay. 1998. Listeria monocytogenes invasion of epithelial cells requires the MEK-1/ERK-2 mitogen-activated protein kinase pathway. Infect. Immun. 66:1106-1112.
38. Terry, C. M., and K. S. Callahan. 1996. Protein kinase C regulates cytokine-induced tissue factor transcription and procoagulant activity in human endothelial cells. J. Lab. Clin. Med. 127:81-93.
39. Teysseire, N., D. Arnoux, F. George, J. Sampol, and D. Raoult. 1992. von Willebrand factor release, thrombomodulin activity and tissue factor expression in Rickettsia conorii-infected endothelial cells. Infect. Immun. 60:4388-4393.
40. Toossi, Z., B. D. Hamilton, M. H. Phillips, L. E. Averill, J. J. Ellner, and A. Salvekar. 1997. Regulation of nuclear factor-κB and its inhibitor IκB-α/ MAD-3 in monocytes by Mycobacterium tuberculosis and during human tuberculosis. J. Immunol. 159:4109-4116.
41. Toullec, D., P. Pianetti, H. Coste, P. Bellevergue, T. Grand-Perret, M. Ajakane, V. Baudet, P. Boissin, E. Boursier, F. Loriolle, L. Duhamel, D. Charon, and J. Kirilovsky. 1991. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem. 266:15771-15781.
42. Whelan, J., P. Ghersa, T. Hooft van Huijsduijnen, J. Gray, G. Chandra, F. Talabot, and J. F. DeLamarter. 1991. An NF kappa B-like factor is essential but not sufficient for cytokine induction of endothelial leukocyte adhesion molecule 1 (ELAM-1) gene transcription. Nucleic Acids Res. 19:2645-2653.