Neurochemical characterization of the vestibular nerves in women with vulvar vestibulitis syndrome

Gynecologic and Obstetric Investigation

Volumn 48, Issue 4, 1999, Pages 270-275

  Bohm Starke, Nina ^a   Hilliges, Marita ^b   Falconer, Christian ^a   Rylander, Eva ^a  

^a DANDERYD HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Chronic pain; Dyspareunia; Immunohistochemistry; Intraepithelial nerves; Vestibulitis

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; GALANIN; NEUROPEPTIDE; NEUROPEPTIDE Y; SUBSTANCE P; VASOACTIVE INTESTINAL POLYPEPTIDE;

ADOLESCENT; ADULT; ARTICLE; CHRONIC PAIN; CLINICAL ARTICLE; CONTROLLED STUDY; DYSPAREUNIA; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NERVE ENDING; NERVE FIBER; NEUROCHEMISTRY; NOCICEPTIVE RECEPTOR; PRIORITY JOURNAL; PUNCH BIOPSY; VULVAR VESTIBULITIS;

EID: 0032722443     PISSN: 03787346     EISSN: None     Source Type: Journal    
DOI: 10.1159/000010198     Document Type: Article

References (30)

1. Baggish MS, Miklos JR: Vulvar pain syndrome: A review. Obstet Gynecol Surv 1995; 50:618-627.
2. Friedrich EG Jr: Vulvar vestibulitis syndrome. J Reprod Med 1987;32:110-114.
3. Bohm-Starke N, Hilliges M, Falconer C, Rylander E: Increased intraepithelial innervation in women with vulvar vestibulitis syndrome. Gynecol Obstet Invest 1998;4:256-260.
4. Westrom LV, Willen R: Vestibular nerve fiber proliferation in vulvar vestibulitis syndrome. Obstet Gynecol 1998;91:572-576.
5. Coons AH: Fluorescent antibody methods; in Danelli JF (ed): General Cytochemical Methods. New York Academic Press. 1958, pp 399-422.
6. Maggi C: The pharmacology of the efferent function of sensory nerves. J Auton Pharmacol 1991;11:173-208.
7. Levine J, Fields H, Basbaum A: Peptides and the primary afferent nociceptor. J Neurosci 1993;13:2273-2286.
8. Lundberg JM, Hökfelt T: Multiple co-existence of peptides and classical transmitters in peripheral autonomie and sensory neurons - Functional and pharmacological implications. Prog Brain Res 1986;68:241-262.
9. Rang HP, Bevan S, Dray A: Nociceptive peripheral neurons: Cellular properties; in Wall PD, Meltzack R (eds): Textbook of Pain, ed. 3. Edinburgh, Churchill Livingstone, 1994, pp 57-78.
10. Ljungberg A, Johansson O: Methodological aspects on immunohistochemistry in dermatology with special reference to neuronal markers. Histochem J 1993;25:735-745.
11. Arnér S, Meyerson BA: Lack of analgesic effect of opioids on neuropathic and idiopathic forms of pain. Pain 1988;33:11-23.
12. Bergeron S, Binik YM, Khalife S, Pagidas K: Vulvar vestibulitis syndrome: A critical review. Clin J Pain 1997;13:27-42.
13. Marinoff SC, Turner ML: Valvular vestibulitis syndrome: An overview. Am J Obstet Gynecol 1991;165:1228-1233.
14. Dray A, Urban L, Dickenson A: Pharmacology of chronic pain. Trends Pharmacol Sci 1994; 15:190-197.
15. Levine J, Taiwo Y: Inflammatory pain; in Wall PD, Meltzack R (eds): Textbook of Pain, ed 3. Edinburgh, Churchill Livingstone, 1994, pp 45-56.
16. Meyer RA, Campell JN: Peripheral neural mechanisms of nociception; in Wall PD, Meltzack R (eds): Textbook of Pain, ed 3. Edinburgh, Churchill Livingstone, 1994, pp 13-44.
17. Neumann S, Doubell TP, Leslie T, Woolf CJ: Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons. Nature 1996;384:360-364.
18. Pyka RE, Wilkinson EJ, Friedrich EG Jr, Croker BP: The histopathology of vulvar vestibulitis syndrome. Int J Gynecol Pathol 1988;7:249-257.
19. Prayson RA, Stoler MH, Hart WR: Vulvar vestibulitis. A histopathologic study of 36 cases, including human papillomavirus in situ hybridization analysis. Am J Surg Pathol 1995; 19:154-160.
20. Chadha S, Gianotten WL, Drogendijk AC, Weijmar Schultz WC, Blindemann LA, van der Meijden WI: Histopathologic features of vulvar vestibulitis. Int J Gynecol Pathol 1998;17: 7-11.
21. Lundqvist EN, Hofer PA, Olofsson JI, Sjoberg I: Is vulvar vestibulitis an inflammatory condition? A comparison of histological findings in affected and healthy women. Acta Derm Venerol 1997;77:319-322.
22. McKay M: Vulvodynia. Diagnostic patterns. Dermatol Clin 1992;10:423-433.
23. Westrom L: Dyspareunia caused by vulvar vestibulitis-good results of surgical interventions. Lakartidningen 1992;89;1460-1461.
24. Bergeron S, Bouchard C; Fortier M, Binik YM, Khalife S: The surgical treatment of vulva vestibulitis syndrome: A follow-up study. J Sex Marital Ther 1997;23:317-325.
25. Goetsch MF: Simplified surgical revision of the vulvar vestibule for vulvar vestibulitis. Am J Obstet Gynecol 1996;174:1701-1705.
26. Bornstein J, Zarfati D, Goldik Z, Abramovici H: Perineoplasty compared with vestibuloplasty for severe vulvar vestibulitis. Br J Obstet Gynaecol 1995;102:652-655.
27. Hökfelt T, Zhan X, Wiesenfeld-Hallin Z: Messenger plasticity in primary sensory neurons following axotomy and its functional implications. Trends Neurosci 1994;17:22-30.
28. Devor M: The pathophysiology of damaged peripheral nerves; in Wall PD, Meltzack R (eds): Textbook of Pain, ed 3. Edinburgh, Churchill Livingstonc. 1994, pp 79-100.
29. McLachlan EM, Jänig W, Devor M, Michaelis M: Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia. Nature 1993;363:543-546.
30. Lundeberg T: Pain physiology and principles of treatment. Scand J Rehabil Med Suppl 1995; 32:13-42.