The schistosome granuloma: An immunoregulatory organelle

Microbes and Infection

Volumn 1, Issue 7, 1999, Pages 499-504

  Rumbley, Catherine A ^a   Phillips, S Michael ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; FAS ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; MESSENGER RNA; PROTEIN BCL 2;

ANIMAL MODEL; APOPTOSIS; CELLULAR IMMUNITY; GRANULOMA; HOST PARASITE INTERACTION; IMMUNE RESPONSE; IMMUNOREGULATION; LIVER GRANULOMA; LYMPHOCYTE MIGRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS;

ANIMALIA; SCHISTOSOMA; SCHISTOSOMA MANSONI;

EID: 0032721658     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1286-4579(99)80088-4     Document Type: Article

References (46)

1. Boros D.L. The role of cytokines in the formation of the schistosome egg granuloma. Immunobiology. 191:1994;441-450.
2. Cheever A.W. Differential regulation of granuloma size and hepatic fibrosis in schistosome infections. Memorias do Instituto Oswaldo Cruz. 92:1997;689-692.
3. Cheever A.W., Byron J.E., von Lichtenberg F. Immunopathology of Schistosoma japonicum infections in athymic mice. Parasite Immunol. 7:1985;387.
4. Cheever A.W., Duvall R.H., Tallack T.A. Differences in hepatic fibrosis and granuloma size in several strains of mice infected with Schistosoma japonicum. Am. J. Trop. Med. Hyg. 33:1984;602.
5. Cheever A.W., Xu Y., Macedonia J.G., Cox T., Hieny S., Sher A. The role of cytokines in the pathogenesis of hepatic granulomatous disease in Schistosoma mansoni infected mice. Memorias do Instituto Oswaldo Cruz. 87:1992;81-85.
6. + Th1-type lymphocytes. J. Immunol. 150:1993;1413-1421.
7. Doenhoff M., Musallam R., Bain J., McGregor A. Studies on the host-parasite relationship in Schistosoma mansoni-infected mice: the immunological dependence of parasite egg excretion. Immunology. 35:1978;771-778.
8. Else K.J., Entwhistle G.M., Grencis R.K. Correlations between worm burden and markers of Th1 and Th2 cell subset induction in an inbred mouse infected with Trichuris muris. Parasite Immunol. 15:1993;595-600.
9. Grzych J.M., Pearce E., Cheever A., Caulada Z.A., Caspar P., Heiny S., Lewis F., Sher A. Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni. J. Immunol. 146:1991;1322-1327.
10. Henderson G.S., Lu X., McCurley T.L., Colley D.G. In vivo molecular analysis of lymphokines involved in the murine immune response during Schistosoma mansoni infection. II. Quantification of IL-4 mRNA IFN-gamma mRNA and IL-2 mRNA levels in the granulomatous livers, mesenteric lymph nodes and spleens during the course of modulation. J. Immunol. 148:1992;2261.
11. Henderson G.S., Nix N.A., Montesano M.A., Gold D., Freeman G.L., Jr M.C, Curley T.L., Colley D.G. Two distinct pathological syndromes in male CBA/J inbred mice with chronic Schistosoma mansoni infections. Am. J. Pathol. 142:1993;703-714.
12. King C.L., Medhat A., Malhotra I., Nafeh M., Helmy A., Khaudary J., Ibrahim S., El-Sherbiny M., Zaky S., Stupi R.J., Brustoski K., Shehata M., Shata M.T. Cytokine control of parasite-specific anergy in human urinary schistosomiasis, IL-10 modulates lymphocyte reactivity. J. Immunol. 156:1996;4715-4721.
13. King C.L., Nutman T.B. Biological role of T cell subsets in helminth infections. Chem. Immunol. 54:1992;136.
14. King C.L., Xianli J., June C.H., Abe R., Lee K.P. CD28-deficient mice generate an impaired Th2 response to Schistosoma mansoni infection. Eur. J. Immunol. 26:1996;2448-2455.
15. Lammie P.J., Linette G.P., Phillips S.M. Characterization of Schistosoma mansoni antigen-reactive T cell clones that form granulomas in vitro. J. Immunol. 134:1985;4170-4175.
16. Lawley T.J., Ottesen E.A., Hiatt R.A., Gazze L.A. Circulating immune complexes in acute schistosomiasis. Clin. Exp. Immunol. 37:1979;221-227.
17. Lukacs N.W., Chensue S.W., Strieter R.M., Warmington K., Kunkel S.L. Inflammatory granuloma formation is mediated by TNF-alpha-inducible intercellular adhesion molecule. J. Immunol. 152:1994;5883-5889.
18. Mathew R.C., Boros D.L. Anti-L3T4 antibody treatment suppresses hepatic granuloma formation and abrogates antigen-induced interleukin-2 production in Schistosoma mansoni infection. Infect. Immun. 54:1986;820-826.
19. + soluble suppressor factor. J. Immunol. 136:1986;1093.
20. Mosmann T.R., Coffman R.L. Two types of mouse helper T cell clones: implications for immune regulation. Immunol. Today. 3:1987;223.
21. Ohta K., Sawamoto S., Nakajima M., Kubota S., Tanaka Y., Miyasaka T., Nagai A., Hirai K., Mano K., Miyashita H. The prolonged survival of human eosinophils with interleukin-5 and its inhibition by theophylline via apoptosis. Clin. Exp. Allergy. 26:1996;10-15.
22. Olds G.R., Mahmoud A.A. Role of host granulomatous response in murine schistosomiasis mansoni. Eosinophil-mediated destruction of eggs. J. Clin. Invest. 66:1980;1191-1199.
23. Osman A., EelRidi R., Guirguis N., Dean D.A. Identification of Schistosoma mansoni antigens recognized by T cells of C57BL/6 mice immunized with gamma-irradiated cercariae. J. Parasitol. 80:1994;421-431.
24. Pearce E.J., Caspar P., Grzych J.M., Lewis F.A., Sher A. Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth Schistosoma mansoni. J. Exp. M. 173:1991;159-166.
25. Phillips S.M., Colley D.G. Immunologic aspects of host responses to schistosomiasis: resistance immunopathology and eosinophil involvement. Prog. Allergy. 24:1978;49-182.
26. Phillips S.M., Diconza J.J., Gold J.A., Reid W.A. Schistosomiasis in the congenitally athymic (nude) mouse. I. Thymic dependency of eosinophilia granuloma formation and host morbidity. J. Immunol. 118:1977;594-599.
27. Phillips S.M., Lammie P.J. Immunopathology of granuloma formation and fibrosis in schistosomiasis. Parasitol. Today. 2:1986;296.
28. Phillips S.M., Linette G.P., Doughty B.L., Byram J.E., von Lichtenberg F. In vivo T cell depletion regulates resistance and morbidity in murine schistosomiasis. J. Immunol. 139:1987;919.
29. Radvanyi L.G., Shi Y., Mills G.B., Miller R.G. Cell cycle progression out of G1 sensitizes primary-cultured nontransformed T cells to TCR-mediated apoptosis. Cell. Immunol. 170:1996;260-273.
30. Ragheb S., Boros D.L. Characterization of granuloma T lymphocyte function from Schistosoma mansoni-infected mice. J. Immunol. 142:1989;3239.
31. Reiner N.E., Kamel R., Higashi G.I., El-Naggar A., Aguib M., Ellner J.J., Mahmoud A.A. Concurrent responses of peripheral blood and splenic mononuclear cells to antigenic and mitogenic stimulation in human hepatosplenic schistosomiasis. J. Infect. Dis. 140:1979;162-168.
32. Reiner S.L., Locksley R.M. The worm and protozoa: Stereotyped responses or distinct antigens? Parasit. Today. 9:1993;258.
33. Rumbley C.A., Zekavat S.A., Sugaya H., Perrin P.J., Ramadan M.A., Phillips S.M. The schistosome granuloma: characterization of lymphocyte migration activation and cytokine production. J. Immunol. 161:1998;4129-4137.
34. Sabin E.A., Araujo M.I., Carvalho E.M., Pearce E.J. Impairment of tetanus toxoid-specific Th1-like immune responses in humans infected with Schistosoma mansoni. J. Infect. Dis. 173:1996;269-272.
35. + cells at the site of antigen deposition predicts the development of a T helper 2 cell response to Schistosoma mansoni eggs. J. Immunol. 155:1995;4844-4853.
36. + T lymphocytes correlates with down-regulation of TH1 cytokine synthesis in helminth infection. J. Immunol. 147:1991;2713.
37. Stadecker M.J., Colley D.G. Report from a symposium: The role of immunological mechanisms in the induction and regulation of granulomatous hypersensitivity to egg antigens of Schistosoma mansoni. Parasitol. Today. 8:1992;218.
38. Tsuyuki S., Bertrand C., Erard F., Trifilieff A., Tsuyuki J., Wesp M., Anderson G.P., Coyle A.J. Activation of the Fas receptor on lung eosinophils leads to apoptosis and the resolution of eosinophilic inflammation of the airways. J. Clin. Invest. 96:1995;2924-2931.
39. Ucker D.S., Hebshi L.D., Blomquist J.F., Torbett B.E. Physiological T-cell death: susceptibility is modulated by activation aging and transformation but the mechanism is constant. Immunol. Rev. 142:1994;273-299.
40. von Lichtenberg F. Studies on granuloma formation. III. Antigen sequestration and destruction in the schistosome pseudotubercle. Am. J. Path. 45:1964;75-93.
41. Walker P.R., Kwast-Welfeld J., Gourdeau H., Leblanc J., Neugebauer W., Sikorska M. Relationship between apoptosis and the cell cycle in lymphocytes: roles of protein kinase C tyrosine phosphorylation and AP1. Exp. Cell Res. 207:1993;142-151.
42. Warren K.S., Domingo E.O., Cowan R.B.T. Granuloma formation around schistosome eggs as a manifestation of delayed hypersensitivity. Am. J. Pathol. 51:1967;735.
43. Weller P.F. Eosinophils: structure and functions. Curr. Opin. Immunol. 6:1994;85-90.
44. Wynn T.A., Cheever A.W. Cytokine regulation of granuloma formation in schistosomiasis. Curr. Opin. Immunol. 7:1995;505-511.
45. Wynn T.A., Eltoum I., Cheever A.W., Lewis F.A., Gause W.C., Sher A. Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni. J. Immunol. 151:1993;1430-1440.
46. Xu Y.H., Macedonia J., Sher A., Pearce E., Cheever A.W. Dynamic analysis of splenic Th1 and Th2 lymphocyte functions in mice infected with Schistosoma japonicum. Infect. Immun. 59:1991;2934-2940.